Abstract: Embodiments of the disclosure provide an optical sensing device for a receiver in an optical sensing system. The optical sensing device includes a light concentrator configured to collect a light beam. The light concentrator includes an input aperture configured to collect the light beam, an output aperture configured to output the light beam, and a side surface in contact with the input aperture and the output aperture. The side surface is configured to reflect the collected light beam towards the output aperture. The optical sensing device also includes a photodetector placed behind the light concentrator. The photodetector is configured to receive the light beam collected through the output aperture and convert the light beam to an electrical current.

Abstract: A modular cabin transfer device suitable for large luxury cruise ships includes transfer vehicles and pull rods, where each of the transfer vehicles includes a clamping device, clamping assemblies, and a driving assembly, the upper and lower ends of the clamping device are respectively provided with the clamping assemblies, the clamping device makes the clamping assemblies at the upper and lower ends thereof move toward each other or move backwards, and the clamping assemblies at the upper and lower ends thereof clamp the cabin; the driving assembly is arranged at the lower end of the clamping device, and is configured to drive the transfer vehicle to move; adjacent transfer vehicles are connected by the pull rods.

Abstract: The present disclosure relates to solid forms of Compound 1, or a pharmaceutically acceptable form thereof, a pharmaceutically acceptable salt of Compound 1, or pharmaceutically acceptable solvate thereof, pharmaceutical compositions comprising the same, methods of preparing the same, and methods of treating cancer dependent on a farnesylated protein, using the same.

Abstract: A plurality of modules are arranged on the broadside of a ship, each module includes a housing, and the housing is provided with a composite gas supply assembly, a composite airbag assembly, an intelligent control assembly, and a mechanical transmission assembly; the intelligent control assembly is configured for predicting the impact energy and a collision angle of a collision object, sending an inflation instruction to the composite gas supply assembly, inflating a large airbag to a proper air pressure, inflating a small airbag to a rated air pressure, and sending an angle adjustment instruction to the mechanical transmission assembly to adjust the collision angle of the small airbag; the large airbag is matched with the small airbag to fully absorb a collision force vertically acting on the surface of a hull.

Abstract: In one example, a Light Detection and Ranging (LiDAR) module is provided. The LiDAR module comprises a semiconductor integrated circuit comprising a micro-electromechanical system (MEMS) formed on a surface of a silicon substrate, and a controller, the MEMS comprising a polygon assembly, the polygon assembly comprising: a polygon; a support structure connected to the polygon and forming a stack with the polygon along a rotation axis; a plurality of anchors formed on the surface of the substrate; and a plurality of actuators, each actuator of the plurality of actuators being connected between the support structure and an anchor of the plurality of actuators. The controller is configured apply a voltage across each actuator of the plurality of actuators, wherein the voltage causes each actuator to exert a torque on the support structure to rotate the polygon around the rotation axis by a target rotation angle.

Abstract: The present disclosure relates to solid forms of Compound 1, or a pharmaceutically acceptable form thereof, a pharmaceutically acceptable salt of Compound 1, or pharmaceutically acceptable solvate thereof, pharmaceutical compositions comprising the same, methods of preparing the same, and methods of treating cancer dependent on a farnesylated protein, using the same.

Abstract: Embodiments of the disclosure provide an optical sensing system containing a diffractive optical element, and an optical sensing method using the same. For example, the optical sensing system includes a laser emitter configured to emit an optical signal. The optical sensing system further includes a steering device configured to direct the emitted optical signal toward an environment surrounding the optical sensing system. The optical sensing system additionally includes a diffractive optical element configured to diffract the optical signal returning from the environment to form a plurality of beams focusing at a plurality of spots on a focal plane. The optical sensing system additionally includes a photosensor array placed at the focal plane, configured to detect the plurality of beams diffracted by the diffractive optical element at the plurality of spots, wherein the photosensor array comprises a plurality of sensitive elements.

Abstract: Embodiments of the disclosure provide a transmitter containing a Risley prism-based scanning mechanism, an optical sensing system containing the same, and an optical sensing method using the same. For example, the optical sensing system includes a laser emitter configured to sequentially emit a series of optical signals. The optical sensing system further includes a plurality of prisms configured to receive the series of optical signals and sequentially direct the series of optical signals at different directions in an angle of view of the optical sensing system. At least one prism of the plurality of prisms is configured to rotate relative to at least one other prism of the plurality of prisms to refract the optical signals towards the respective different directions. The optical sensing system additionally includes a receiver configured to receive at least a portion of the series of optical signals reflected from an environment surrounding the optical sensing system.

Abstract: A transmitter for light detection and ranging (LiDAR) is provided. The transmitter includes a plurality of laser sources and a light modulator. Each of the laser sources includes interleaved emitting regions and gaps and is configured to provide a native laser beam in a respective incident direction. The light modulator is configured to receive the native laser beams from the plurality of laser sources in different incident directions and combine the native laser beams into a combined laser beam in a diffraction direction.

Abstract: Embodiments of the disclosure provide a transmitter containing an omni-view peripheral scanning system, an omni-view peripheral scanning system, and an optical sensing method. The optical sensing system includes an optical source configured to sequentially emit optical signals. The optical sensing system further includes an omni-view peripheral scanning system configured to receive the optical signals and sequentially direct the optical signals towards an environment following a peripheral scanning pattern. The peripheral scanning system may include a scanning mirror and a top reflector. Each optical signal may pass through the top reflector towards the scanning mirror, where the scanning mirror is configured to reflect the optical signal back onto the top reflector following a spiral pattern and the top reflector is configured to direct the optical signal towards the environment.

Abstract: Embodiments of the disclosure provide an optical sensing system for two-dimensional (2D) environmental sensing and an optical sensing method for the optical sensing system. The optical sensing system includes a rotary base and a one-dimensional (1D) optical sensing apparatus supported by the rotary base. The 1D optical sensing apparatus includes an optical source configured to emit optical signals, a 1D MEMS scanner configured to direct the optical signals towards an environment surrounding the optical sensing system, and a receiver configured to receive at least a portion of the optical signals reflected from the environment. The rotary base is configured to drive the 1D optical sensing apparatus to rotate around a first axis to scan the optical signals in a first dimension and the 1D MEMS scanner is configured to independently rotate around a second axis to scan the optical signals in a second dimension in the 2D environmental sensing.

Abstract: Embodiments of the disclosure provide optical sensing systems, optical sensing methods, and integrated transmitter/receiver (TX/RX) modules. An exemplary optical sensing system includes an integrated TX/RX module and a controller coupled to the integrated TX/RX module. The integrated TX/RX module includes a laser emitter, one or more optics, and a receiver frontend. The laser emitter is configured to emit an optical signal toward the one or more optics. The one or more optics are configured to form the optical signal received from the laser emitter into a predefined shape and direct the optical signal having the predefined shape to an environment surrounding the optical sensing system. The receiver frontend is configured to receive a returned optical signal from the environment and convert the returned optical signal into an electrical signal. The laser emitter, the one or more optics, and the receiver frontend are assembled in a single package.

Abstract: Methods and kits for detecting and/or quantitating target proteins in biological samples. In particular, the method comprises capture and immobilization of the target protein, protein denaturation, proteolytic digestion, and analysis using a mass spectrometry-based technique.

Abstract: Embodiments of the present disclosure disclose a Cupriavidus metallidurans CML2, wherein the Cupriavidus metallidurans CML2 is deposited in the China Center for Type Culture Collection with a depository number CCTCC NO: M20231365, and a 16s rDNA of the Cupriavidus metallidurans CML2 has a nucleotide sequence of SEQ ID No. 1.

Abstract: A grating for a steering mirror of a LiDAR system is made without a metal coating. The grating comprising a plurality of ridges defined by a period. The period has a width that is equal to or less than a wavelength of a laser of the LiDAR system. The ridges can be made of crystalline silicon to form a high-contrast grating.

Abstract: A MEMS-based Wavelength Selectable Switch (WSS), used classically for demultiplexing fiber optic communications, is re-purposed to act as a filter. A light emitter provides a light beam with its wavelength detected by a wavelength detector. A light condenser directs reflected light from the light emitter to an input of the WSS. The WSS is controllable to provide a selected wavelength band to a selected output of the WSS, where it is detected by a photodetector. Other wavelengths are discarded by the WSS at other outputs. A controller is configured to control the WSS to select the selected wavelength band based on a detected wavelength from the wavelength detector.

Abstract: Embodiments of the disclosure provide an optical sensing system, a method for controlling a receiver gain in the optical sensing system, and a receiver in the optical sensing system. The exemplary optical sensing system includes a transmitter configured to emit light beams at a plurality of vertical detection angles to scan an object. The optical sensing system further includes a receiver having a detector configured to detect the light beams returned by the object. The optical sensing system also includes a controller configured to dynamically vary a gain of the detector for detecting the light beams of the respective vertical detection angles.

Abstract: The present invention provides crystalline forms of (6S,7S)-6-fluoro-7-(2-fluoro-5-methylphenyl)-3-(tetrahydro-2H-pyran-4-yl)-5,6,7,8-tetrahydropyrido[2,3-d]pyrimidine-2,4(1H,3H)-dione (“Compound I”). Also provided are related pharmaceutical compositions, methods of preparation, and methods of treating hypertrophic cardiomyopathy (HCM), heart failure with preserved ejection fraction (HFpEF), diastolic dysfunction, left ventricular hypertrophy, and other cardiac diseases.

Abstract: An array of MEMS mirrors intercept a laser beam and redirect it toward an environment to be detected. A controller is configured to control the laser and the array of MEMS mirrors to generate a plurality of irregular patterns, such as a Hadamard pattern. The controller controls the laser and the array of MEMS mirrors to generate a plurality of Hadamard patterns on a single scan line at different times, such that all pixel positions in the scan line are impacted by one of the redirected beams from the mirror array at least once. The detected intensities of all the pixel reflections in each pattern are combined to give a total combined intensity for each of the different times. The Hadamard pattern is used to decode the various total combined intensities for a scan line to determine an intensity of each pixel in the scan line.

Abstract: Embodiments of the disclosure provide a laser beam generation system. The laser beam generation system includes a first laser chip configured to generate a first polarized laser beam and a second laser chip configured to generate a second polarized laser beam. The laser beam generation system also includes a polarizer configured to combine the first polarized laser beam and the second polarized laser beam to generate a third laser beam.