Patents by Inventor Yuefen Zhou

Yuefen Zhou has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 8546602
    Abstract: The invention is directed to 5,6-dihydro-1H-pyridin-2-one compounds of Formula I wherein X is N, and A is and compounds used to synthesize the compounds of Formula I.
    Type: Grant
    Filed: August 6, 2012
    Date of Patent: October 1, 2013
    Assignee: Anadys Pharmaceuticals, Inc.
    Inventors: Chinh V. Tran, Frank Ruebsam, Douglas E. Murphy, Peter Dragovich, Yuefen Zhou, Lijian Chen, David Kucera, Fritz Blatter, Martin Viertelhaus
  • Publication number: 20120302744
    Abstract: The invention is directed to 5,6-dihydro-1H-pyridin-2-one compounds of Formula I wherein X is N, and A is and compounds used to synthesize the compounds of Formula I.
    Type: Application
    Filed: August 6, 2012
    Publication date: November 29, 2012
    Applicant: Anadys Pharmaceuticals, Inc.
    Inventors: Chinh V. Tran, Frank Ruebsam, Douglas E. Murphy, Peter Dragovich, Yuefen Zhou, Lijian Chen, David Kucera, Fritz Blatter, Martin Viertelhaus
  • Patent number: 8101800
    Abstract: The invention is directed to a 5,6-dihydro-1H-pyridin-2-one compound selected from:
    Type: Grant
    Filed: March 8, 2011
    Date of Patent: January 24, 2012
    Assignee: Anadys Pharmaceuticals, Inc.
    Inventors: Chinh V. Tran, Frank Ruebsam, Douglas E. Murphy, Peter Dragovich, Yuefen Zhou, Lijian Chen, David Kucera, Fritz Blatter, Martin Viertelhaus
  • Publication number: 20110166344
    Abstract: The invention is directed to 5,6-dihydro-1H-pyridin-2-one compounds of Formula I wherein X is N, and A is and compounds used to synthesize the compounds of Formula I.
    Type: Application
    Filed: March 8, 2011
    Publication date: July 7, 2011
    Applicant: Anadys Pharmaceuticals, Inc.
    Inventors: Chinh V. Tran, Frank Ruebsam, Douglas E. Murphy, Peter Dragovich, Yuefen Zhou, Lijian Chen, David Kucera, Fritz Blatter, Martin Viertelhaus
  • Patent number: 7939524
    Abstract: The invention is directed to 5,6-dihydro-1H-pyridin-2-one compounds of Formula I wherein X is N, and A is and pharmaceutical compositions containing such compounds that are useful in treating infections by hepatitis C virus.
    Type: Grant
    Filed: April 2, 2008
    Date of Patent: May 10, 2011
    Assignee: Anadys Pharmaceuticals, Inc.
    Inventors: Chinh V. Tran, Frank Ruebsam, Douglas E. Murphy, Peter Dragovich, Yuefen Zhou, Lijian Chen, David Kucera
  • Patent number: 7834009
    Abstract: The invention is directed to 4-hydroxy-5,6-dihydro-1H-pyridin-2-one compounds of Formula I and pharmaceutical compositions containing such compounds that are useful in treating infections by hepatitis C virus: wherein R6 is X is N, Ring A is a 5- or 6-membered aryl, optionally substituted by 1-3 R8 moieties, n is 2, and R1-R6 and R8 are defined herein.
    Type: Grant
    Filed: August 27, 2007
    Date of Patent: November 16, 2010
    Assignee: Anadys Pharmaceuticals, Inc.
    Inventors: David Ellis, Liansheng Li, Chinh V. Tran, Frank Ruebsam, Yuefen Zhou
  • Publication number: 20100034773
    Abstract: The invention is directed to 5,6-dihydro-1H-pyridin-2-one compounds and pharmaceutical compositions containing such compounds that are useful in treating infections by hepatitis C virus.
    Type: Application
    Filed: April 2, 2008
    Publication date: February 11, 2010
    Applicant: Anadys Pharmaceuticals, Inc.
    Inventors: Chinh V. Tran, Frank Ruebsam, Douglas E. Murphy, Peter Dragovich, Yuefen Zhou, Lijian Chen, David Kucera, Fritz Blatter, Martin Viertelhaus
  • Patent number: 7582626
    Abstract: The invention is directed to 5,6-dihydro-1H-pyridin-2-one compounds of Formula I and pharmaceutical compositions containing such compounds that are useful in treating hepatitis C virus infections: wherein Z is X is N or CR9; Y is ā€”(CR4R5)nā€”; n is 2, 3, 4, or 5; and R1 through R9 are defined herein.
    Type: Grant
    Filed: December 12, 2007
    Date of Patent: September 1, 2009
    Assignee: Anadys Pharmaceuticals, Inc.
    Inventors: Chinh V. Tran, Frank Ruebsam, Yuefen Zhou, Peter Dragovich, Alan X. Xiang
  • Publication number: 20090111798
    Abstract: The invention is directed to 5,6-dihydro-1H-pyridin-2-one compounds and pharmaceutical compositions containing such compounds that are useful in treating infections by hepatitis C virus.
    Type: Application
    Filed: December 12, 2007
    Publication date: April 30, 2009
    Inventors: Chinh V. Tran, Frank Ruebsam, Yuefen Zhou, Peter Dragovich, Alan X. Xiang
  • Publication number: 20090062263
    Abstract: The invention is directed to 4-hydroxy-5,6-dihydro-1H-pyridin-2-one compounds and pharmaceutical compositions containing such compounds that are useful in treating infections by hepatitis C virus.
    Type: Application
    Filed: August 27, 2007
    Publication date: March 5, 2009
    Inventors: David Ellis, Liansheng Li, Chinh V. Tran, Frank Ruebsam, Yuefen Zhou
  • Publication number: 20080292588
    Abstract: The invention is directed to 1-methyl-benzo[1,2,4]thiadiazine 1-oxide derivatives and pharmaceutical compositions containing such compounds that are useful in treating infections by hepatitis C virus.
    Type: Application
    Filed: May 16, 2008
    Publication date: November 27, 2008
    Applicant: Anadys Pharmaceuticals, Inc.
    Inventors: Yuefen Zhou, Thomas Bertolini, Liansheng Li
  • Publication number: 20080275032
    Abstract: The invention is directed to pyridazinone compounds and pharmaceutical compositions containing such compounds that are useful in treating infections by hepatitis C virus.
    Type: Application
    Filed: September 11, 2007
    Publication date: November 6, 2008
    Inventors: Yuefen Zhou, Liansheng Li, Stephen E. Webber, Peter Dragovich, Douglas E. Murphy, Chinh V. Tran, Jingjing Zhao, Frank Ruebsam
  • Patent number: 7425552
    Abstract: The invention is directed to pyridazinone compounds of Formula I and pharmaceutical compositions containing compounds of Formula I wherein R1 and R2 are independently H, alkyl, cycloalkyl, aryl, or heterocyclyl; and Ring A is 5 or 6-membered aryl or heterocyclyl. The invention also encompasses methods of using a compound of Formula I in the treatment of hepatitis C virus infections.
    Type: Grant
    Filed: December 16, 2005
    Date of Patent: September 16, 2008
    Assignee: Anadys Pharmaceuticals, Inc.
    Inventors: Yuefen Zhou, Liansheng Li, Stephen E. Webber
  • Publication number: 20080214529
    Abstract: The invention is directed to saturated fused [1,2-b]pyridazinone compounds and pharmaceutical compositions containing such compounds that are useful in treating infections by hepatitis C virus.
    Type: Application
    Filed: December 12, 2007
    Publication date: September 4, 2008
    Inventors: Frank Ruebsam, Zhongxiang Sun, Benjamin Ayida, Yuefen Zhou, Alan X. Xiang
  • Publication number: 20080188466
    Abstract: The invention is directed to pyridazinone compounds and pharmaceutical compositions containing such compounds that are useful in treating infections by hepatitis C virus.
    Type: Application
    Filed: September 26, 2007
    Publication date: August 7, 2008
    Applicant: ANADYS PHARMACEUTICALS, INC.
    Inventors: Peter Dragovich, Yuefen Zhou, Stephen E. Webber
  • Publication number: 20080090814
    Abstract: The invention is directed to pyridazinone compounds and pharmaceutical compositions containing such compounds that are useful in treating infections by hepatitis C virus.
    Type: Application
    Filed: June 21, 2007
    Publication date: April 17, 2008
    Applicant: Anadys Pharmaceuticals, Inc.
    Inventors: David Ellis, Stephen Webber, Yuefen Zhou, Peter Dragovich
  • Publication number: 20070197533
    Abstract: The invention relates to antibacterial 3,5-diaminopiperidine-substituted aromatic and heteroaromatic compounds and pharmaceutical compositions thereof. This invention also relates to a method of using such compounds in the treatment of bacterial infections in mammals, especially humans.
    Type: Application
    Filed: April 12, 2007
    Publication date: August 23, 2007
    Applicant: Anadys Pharmaceuticals, Inc.
    Inventors: Yuefen Zhou, Dionisios Vourloumis, Vlad Gregor, Geoffrey Winters, Thomas Hermann, Benjamin Ayida, Zhongxiang Sun, Douglas Murphy, Klaus Simonsen
  • Patent number: 7223759
    Abstract: The invention relates to antibacterial 3,5-diaminopiperidine-substituted aromatic and heteroaromatic compounds and pharmaceutical compositions thereof. This invention also relates to a method of using such compounds in the treatment of bacterial infections in mammals, especially humans.
    Type: Grant
    Filed: September 15, 2004
    Date of Patent: May 29, 2007
    Assignee: Anadys Pharmaceuticals, Inc.
    Inventors: Yuefen Zhou, Dionisios Vourloumis, Vlad E. Gregor, Geoffrey C. Winters, Thomas Hermann, Benjamin Ayida, Zhongxiang Sun, Douglas Murphy, Klaus B. Simonsen
  • Publication number: 20060189602
    Abstract: The invention is directed to pyridazinone compounds and pharmaceutical compositions containing such compounds that are useful in treating infections by hepatitis C virus.
    Type: Application
    Filed: December 16, 2005
    Publication date: August 24, 2006
    Applicant: Anadys Pharmaceuticals, Inc.
    Inventors: Yuefen Zhou, Liansheng Li, Stephen Webber
  • Publication number: 20050239827
    Abstract: The invention relates to antibacterial 3,5-diaminopiperidine-substituted aromatic and heteroaromatic compounds and pharmaceutical compositions thereof. This invention also relates to a method of using such compounds in the treatment of bacterial infections in mammals, especially humans.
    Type: Application
    Filed: September 15, 2004
    Publication date: October 27, 2005
    Inventors: Yuefen Zhou, Dionisios Vourloumis, Vlad Gregor, Geoffrey Winters, Thomas Hermann, Benjamin Ayida, Zhongxiang Sun, Douglas Murphy, Klaus Simonsen