Abstract: Provided herein are IL-15 cytokine prodrugs and methods of making and using thereof.

Abstract: Disclosed are methods of identifying pathogens and determining their antimicrobial susceptibility. The methods comprise detecting biomarkers in a test sample, locating the sample in a phylogenetic tree based on biomarker information, obtaining drug susceptibility prediction rules based on the phylogenetic tree positioning of the sample, and determining the drug susceptibility of a pathogen according to the prediction rules. Further disclosed are an application of the phylogenetic tree in the preparation of pathogen identification and/or drug susceptibility diagnostic product, and a pathogen identification and drug susceptibility diagnostic kit.

Abstract: Disclosed is a heterojunction solar cell with a hole transport layer. The solar cell includes a bottom electrode, a GaAs substrate, an InGaAs epitaxial layer, a hole transport layer, a molybdenum disulfide layer and a top electrode in order from bottom to top; the hole transport layer is a 2,2?,7,7?-tetra[N,N-bis(4-methoxyphenyl)amino]-9,9?-spirobifluorene film. Also disclosed is a preparation method of the heterojunction solar cell with a hole transport layer. The heterojunction solar cell of the present invention not only has simple preparation process and low process cost, but also has high photoelectric conversion efficiency, and the preparation method is an effective method for preparing a novel heterojunction solar cell.

Abstract: A computer-controlled apparatus and method for producing metallic parts by laser melting selected regions of a layer(s) of metal powder at a target area are disclosed. The system includes devices for preheating and maintaining a relatively high temperature, e.g. 400° C., of the metal powder so as to join the metal powder together with relatively low laser power, e.g. a 200W CO2 laser. A major powder depositing mechanism with a scraper and a depositing system for a secondary powder are included in the apparatus that allows the powders to be delivered to the target area for selective melting. The metal powder is preheated at either a dispensing cylinder or the target area through thermal conduction and/or is also heated by a heating plate positioned above the platform through radiation. The corresponding machine structures, such as a motion system and a working chamber, are designed to be able to withstand and operated under the high temperature environment.

Abstract: A computer-controlled apparatus and method for producing metallic parts by laser melting selected regions of a layer(s) of metal powder at a target area are disclosed. The system includes devices for preheating and maintaining a relatively high temperature, e.g. 400° C., of the metal powder so as to join the metal powder together with relatively low laser power, e.g. a 200W CO2 laser. A major powder depositing mechanism with a scraper and a depositing system for a secondary powder are included in the apparatus that allows the powders to be delivered to the target area for selective melting. The metal powder is preheated at either a dispensing cylinder or the target area through thermal conduction and/or is also heated by a heating plate positioned above the platform through radiation. The corresponding machine structures, such as a motion system and a working chamber, are designed to be able to withstand and operated under the high temperature environment.