Abstract: An intra-aortic dual balloon driving pump catheter device is disclosed, including a controlling part adapted to control air pumps to inflate and deflate a first balloon and a second balloon according to a cardiac cycle and an arterial pressure of the catheter end monitored by a monitoring part, such that in diastole the first balloon inflates while the second balloon deflates, and in systole the first balloon deflates while the second balloon inflates, wherein the second balloon deflates and inflates conversely to the synchronized inflation and deflation of the first balloon respectively, the first balloon fully inflates in diastole and fully deflates in systole, and the second balloon fully deflates in diastole and can inflate in systole only to a predetermined percentage of its volume of full inflation.

Abstract: An intra-aortic dual balloon driving pump catheter device is disclosed, including a controlling part adapted to control air pumps to inflate and deflate a first balloon and a second balloon according to a cardiac cycle and an arterial pressure of the catheter end monitored by a monitoring part, such that in diastole the first balloon inflates while the second balloon deflates, and in systole the first balloon deflates while the second balloon inflates, wherein the second balloon deflates and inflates conversely to the synchronized inflation and deflation of the first balloon respectively, the first balloon fully inflates in diastole and fully deflates in systole, and the second balloon fully deflates in diastole and can inflate in systole only to a predetermined percentage of its volume of full inflation.

Abstract: An intra-aortic dual balloon driving pump catheter device having a catheter; a first balloon and a second balloon respectively surrounding the catheter, being arranged successively along the longitudinal direction of the catheter, wherein the position of the first balloon is placed at the distal end of the catheter, and the second balloon is placed immediately adjacent to the proximal end of the first balloon; the first balloon and the second balloon are periodically expanded to a dimension that nearly blocks the aortic blood flow and contracted to a dimension that does not prevent the blood flow from passing through; wherein the first balloon periodically inflates in diastole and deflates in systole working as a pump, while the second balloon conversely deflates in systole and inflates in diastole functioning as a valve, altogether leading to blood pumping from contracting ventricle and keeping driving forward ahead in the aorta.

Abstract: An intra-aortic dual balloon driving pump catheter device having a catheter; a first balloon and a second balloon respectively surrounding the catheter, being arranged successively along the longitudinal direction of the catheter, wherein the position of the first balloon is placed at the distal end of the catheter, and the second balloon is placed immediately adjacent to the proximal end of the first balloon; the first balloon and the second balloon are periodically expanded to a dimension that nearly blocks the aortic blood flow and contracted to a dimension that does not prevent the blood flow from passing through; wherein the first balloon periodically inflates in diastole and deflates in systole working as a pump, while the second balloon conversely deflates in systole and inflates in diastole functioning as a valve, altogether leading to blood pumping from contracting ventricle and keeping driving forward ahead in the aorta.

Abstract: A method for preparing mesenchymal stem cell-derived exosomes on the basis of drug pretreatment, the method for preparing mesenchymal stem cell-derived exosomes comprising: using a statin to pretreat mesenchymal stem cells, and culturing the treated mesenchymal stem cells to collect exosomes secreted thereby. Also provided is an application of a statin in preparing a preparation for promoting the anti-apoptotic abilities and/or homing abilities of mesenchymal stem cells; and further provided is an application of a statin in preparing a preparation for promoting mesenchymal stem cells to secrete exosomes having myocardial infarction microenvironment-improving effects and/or myocardial repair abilities.

Abstract: The present invention relates to an intra-aortic dual balloon pump catheter device. The intra-aortic dual balloon pump comprises: a catheter (2); a first balloon (4) and a second balloon (6) arranged to successively surrounding the catheter along the longitudinal direction of the catheter (2), wherein the position of the first balloon (4) is closer to a catheter end (5) of the catheter (2) than the position of the second balloon (6); the first balloon (4) and the second balloon (6) are periodically expanded to a dimension that blocks the aortic blood flow and contracted to a dimension that does not prevent the blood flow from passing through; wherein the first balloon (4) begins and finishes the inflation earlier than the second balloon (6) in each period of expansion and contraction.

Abstract: The present invention discloses use of a traditional Chinese medicinal composition for preparing medicine for promoting bond marrow-derived mesenchymal stem cell survival in vivo and differentiation into cardiomyocytes. The invention also relates to use of the traditional Chinese medicinal composition for preparing the medicines for treatment of cardiovascular disease in combination with autologous bone marrow-derived mesenchymal stem cells.