Patents by Inventor Yuejun CHEN

Yuejun CHEN has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHOD FOR QUALITY CONTROL AND ENRICHMENT OF HUMAN DOPAMINERGIC NEURAL PRECURSOR CELLS
    Publication number: 20240207324
    Abstract: Provided are a method for identifying, separating and/or enriching dopaminergic neural precursor cells, the method comprising: detecting whether a candidate cell possesses one or more among the following features: CLSTN2+, PTPRO+, NTRK3+, FLRT2+, KITLG+, CD83+, and/or LMX1A+EN1+, and cell products obtained according to the method. Also provided is a method for evaluating a cell product and optimizing a cell product preparation process. The product and methods can be used to treat diseases or disorders of the nervous system.
    Type: Application
    Filed: April 20, 2022
    Publication date: June 27, 2024
    Applicant: SHANGHAI UNIXELL BIOTECHNOLOGY CO., LTD.
    Inventors: Yuejun CHEN, Peibo XU, Ziyan WU
  • METHOD FOR DIFFERENTIATING PLURIPOTENT STEM CELLS INTO DOPAMINERGIC NERVE CELLS IN MIDBRAIN SUBSTANTIA NIGRA
    Publication number: 20230340407
    Abstract: Specific method for differentiating pluripotent stem cells into dopaminergic (A9 mDA) nerve cells in the midbrain substantia nigra is provided. Mature A9 mDA neurons are formed by differentiation, which can express the molecular markers of the midbrain substantia nigra dopaminergic neurons, including TH, FOXA2, EN1, LMX1A, NURR1 and GIRK2, but which rarely express the marker CALB of the ventral tegmental area dopaminergic neurons.
    Type: Application
    Filed: September 14, 2021
    Publication date: October 26, 2023
    Applicant: UniXell Biotechnology
    Inventors: Yuejun CHEN, Wenhao ZHOU, Man XIONG