Abstract: The technical solution of the present disclosure provides an analytical system and an analytical method, which can quickly and automatically capture, recognize and detect samples using a simpler device structure, improve detection efficiency and reduce costs. The analytical system includes: a fluid system, where solution containing sample particles is stored in or flowing through; an optical tweezer arranged towards the fluid system and configured to capture the sample particles in the fluid system; an optical detector configured to detect optical information of the sample particles in the fluid system; and a mass spectrometer arranged at a succeeding stage of the fluid system. The sample particles in the fluid system are at least partially driven by the optical tweezer toward the mass spectrometer.