Abstract: The present disclosure provides a method and a system for refining long chain dicarboxylic acid, said method comprising the following steps: (1) subjecting a long chain dicarboxylic acid fermentation broth or a treated liquid therefrom to a membrane filtration, an acidification/crystallization, a solid-liquid separation and drying to give a long chain dicarboxylic acid crude product; (2) subjecting the long chain dicarboxylic acid crude product to a vacuum distillation to give the long chain dicarboxylic acid product; wherein the pressure in the vacuum distillation is ?100 Pa. By using the refining method according to the present disclosure, the procedure is simplified, and the purity of the obtained product is high, and the disadvantages such as poor quality of the product obtained by crystallization from a solvent and environment pollution caused by a solvent can be overcome.

Abstract: The present disclosure provides method for isolating a long chain dicarboxylic acid such as a substantially pure or pure long chain dicarboxylic acid from a fermentation broth containing microbial cells.

Abstract: The present disclosure provides a method for isolating a long chain dicarboxylic acid from fermentation broth containing microbial cells. Also provided is a substantially pure long chain dicarboxylic acid isolated by the method.

Abstract: The present disclosure provides a method for isolating a long chain dicarboxylic acid from fermentation broth containing microbial cells. Also provided is a substantially pure long chain dicarboxylic acid isolated by the method.

Abstract: A hinge assembly comprising a guide body, a first connection element, a second connection element, a first spring and a second spring; the guide body comprising a first end surface and a second end surface provided at opposite sides respectively, wherein the first end surface is provided with a first guide slot, the second end surface is provided with a second guide slot, and the first guide slot and the second guide slot intersect orthogonally, the first connection element is provided with first connection end extending beyond an end surface of the endpiece, the second connection element is provided with a second connection end extending beyond an end surface of the temple end, the first connection end and the second connection end are hingedly connected and pivoted with each other within the guide body; A glasses frame comprising an endpiece, a temple, and a hinge assembly.

Abstract: The present invention relates to the use of an MAPK signaling pathway inhibitor in the manufacture of a medicament for delaying the degeneration of dopaminergic neurons, in particular to the use in the manufacture of a medicament for treating PD. The MAPK signaling pathway inhibitor of the present invention can effectively delay the degenerative death of dopaminergic neurons and thus can fundamentally achieve the effect of treating PD. According to the present invention, the MAPK signaling pathway inhibitor is prepared into an oral dosage form and thus it does not need to be injected. The therapeutic effect on a patient can be achieved only by oral administration. According to the present invention, the MAPK signaling pathway inhibitor has a better therapeutic effect on PD caused by various causes and is of great significance for the treatment and cure of PD.

Abstract: A hinge assembly comprising a guide body, a first connection element, a second connection element, a first spring and a second spring; the guide body comprising a first end surface and a second end surface provided at opposite sides respectively, wherein the first end surface is provided with a first guide slot, the second end surface is provided with a second guide slot, and the first guide slot and the second guide slot intersect orthogonally, the first connection element is provided with first connection end extending beyond an end surface of the endpiece, the second connection element is provided with a second connection end extending beyond an end surface of the temple end, the first connection end and the second connection end are hingedly connected and pivoted with each other within the guide body; A glasses frame comprising an endpiece, a temple, and a hinge assembly.

Abstract: Disclosed is an apparatus for improving excavating operation characteristic and grading operation characteristic of an excavator. The apparatus includes a solenoid valve group and a hydraulically controlled selector valve. An oil controlling output A1 of the solenoid valve group is configured in series with oil controlling input a1 of the hydraulic control valve. An oil controlling output A2 of the solenoid valve group is configured in series with a pilot control end XBa2 of a multi-port valve group. An oil return port T1 of the solenoid valve group is connected to the hydraulic oil tank. An oil controlling output b1 of the hydraulically controlled selector valve is connected to a pilot control end XAb2 of the multiplexer valve group, and an oil return port T2 of the hydraulically controlled selector valve is connected with the hydraulic oil tank. The apparatus improves operational efficiency and control comfortability.

Abstract: A method for improving excavating operation characteristic and grading operation characteristic of an excavator is disclosed. A hydraulically controlled selector valve is added in a boom confluence control circuit of a hydraulic excavator, and a solenoid valve group is added in the boom confluence control circuit and the bucket/stick confluence control circuit. A controller sends a control signal to switch the solenoid valve group between a disconnected mode and a connected mode. The controller may send out a signal to disconnect the solenoid valve group, to restore a valve spool to a middle position, to restore a boom lifting confluence circuit, and to disconnect a bucket/stick swinging confluence circuit to perform a standard excavation mode. The controller may send out a signal to connect the solenoid valve group to disconnect a boom lifting confluence circuit and to increase a bucket/stick swinging confluence circuit to achieve a grading operation mode.

Abstract: An energy-saving control system of an excavator, including an engine, a main pump (1), a pilot handle, a pilot pressure pump (2), pilot control valves (4), a controller, a main control multi-way valve (3) and an execution mechanism. The main pump controls the execution mechanism via the main control multi-way valve (3). The oil paths connecting the main pump to the execution mechanism are provided with high pressure sensors (6) for transmitting signals to the controller. The main pump adjusts the flow rate thereof according to the pressure of a negative feedback oil path. The oil paths interconnecting the output end of the pilot handle with the main pump is provided with electromagnetic proportional reducing valves (7) and shuttle valves (8). A pilot oil path sequentially passes through the electromagnetic proportional reducing valves (7) and the shuttle valves (8) to control the flow rate of the main pump.

Abstract: Disclosed is an apparatus for improving excavating operation characteristic and grading operation characteristic of an excavator. The apparatus includes a solenoid valve group and a hydraulically controlled selector valve. An oil controlling output A1 of the solenoid valve group is configured in series with oil controlling input a1 of the hydraulic control valve. An oil controlling output A2 of the solenoid valve group is configured in series with a pilot control end XBa2 of a multi-port valve group. An oil return port T1 of the solenoid valve group is connected to the hydraulic oil tank. An oil controlling output b1 of the hydraulically controlled selector valve is connected to a pilot control end XAb2 of the multiplexer valve group, and an oil return port T2 of the hydraulically controlled selector valve is connected with the hydraulic oil tank. The apparatus improves operational efficiency and control comfortability.

Abstract: A method for improving excavating operation characteristic and grading operation characteristic of an excavator is disclosed. A hydraulically controlled selector valve is added in a boom confluence control circuit of a hydraulic excavator, and a solenoid valve group is added in the boom confluence control circuit and the bucket/stick confluence control circuit. A controller sends a control signal to switch the solenoid valve group between a disconnected mode and a connected mode. The controller may send out a signal to disconnect the solenoid valve group, to restore a valve spool to a middle position, to restore a boom lifting confluence circuit, and to disconnect a bucket/stick swinging confluence circuit to perform a standard excavation mode. The controller may send out a signal to connect the solenoid valve group to disconnect a boom lifting confluence circuit and to increase a bucket/stick swinging confluence circuit to achieve a grading operation mode.

Abstract: A projection display device includes a light source; an optical system which modulates light from the light source, and emits the modulated light; a projecting portion which enlarges and projects the light emitted from the optical system; a cabinet which houses the light source, the optical system, and the projecting portion; an opening which is formed in one surface of the cabinet to allow mounting or dismounting of an optical component constituting the optical system, or the light source; a cover which covers the opening; and a holding portion which holds the cover in such a manner that the cover is allowed to slide in a direction along the one surface.

Abstract: A projection display device includes a light source; an optical system which modulates light from the light source, and emits the modulated light; a projecting portion which enlarges and projects the light emitted from the optical system; a cabinet which houses the light source, the optical system, and the projecting portion; an opening which is formed in one surface of the cabinet to allow mounting or dismounting of an optical component constituting the optical system, or the light source; a cover which covers the opening; and a holding portion which holds the cover in such a manner that the cover is allowed to slide in a direction along the one surface.