Patents by Inventor Yufu Li

Yufu Li has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20200171197
    Abstract: The present invention relates generally to agents and devices for promoting hemostasis and tissue sealing and, more particularly, to hemostatic pads comprising bioabsorbable scaffolds that can deliver lyophilized hemostasis promoting proteins, such as fibrinogen and thrombin, to a wound site or injured organ or tissue.
    Type: Application
    Filed: February 5, 2020
    Publication date: June 4, 2020
    Inventors: Randolph W. Hubbell, James Eckhardt, Jerome Riebman, Yufu Li, Michael Elser
  • Patent number: 10646623
    Abstract: An implantable medical device, which comprises a device substrate, a coating on the substrate which includes a drug, and a protective layer which overlies the coating. The protective layer comprises a polymer selected from the group consisting of polylactic acid, polyglycolic acid and a lactic acid/glycolic acid copolymer having a weight average molecular weight of not more than 40,000.
    Type: Grant
    Filed: December 1, 2017
    Date of Patent: May 12, 2020
    Assignee: DePuy International Limited
    Inventors: Yufu Li, Deborah Schachter, Raymond S. Shissias, Sandra Wechsler
  • Publication number: 20200022843
    Abstract: The present invention is directed to a flowable hemostatic paste comprising a crosslinked carboxymethyl cellulose and at least one non-toxic dispersant. More specifically the present invention relates to a hemostatic paste containing citric acid cross-linked CMC, which is suspended or dispersed as a powder in a mixture of a first non-toxic glycerol-containing hygroscopic dispersant and a second non-toxic alcohol functionalized dispersant comprising propylene glycol or 1,3-butanediol.
    Type: Application
    Filed: August 6, 2018
    Publication date: January 23, 2020
    Inventors: Dengmin Feng, Ling Teng, Yanhui Zhang, Guojun Ni, Yufu Li, Xiang Wan
  • Publication number: 20190347194
    Abstract: Methods, apparatus, and system to compress a data file to form a compressed data file. The data file may be used to configure control of hardware, such as peripheral hardware. The compressed data file may be stored locally or transmitted to another computer device. The compressed data file may be stored in a flash memory. The compressed data file may require less space in flash memory components, relative to flash memory suitable to hold the (original, pre-compressed) data file. Compression and/or decompression may be performed by, for example, a flash memory controller. The compressed data file may be decompressed dynamically, on an as-needed basis, to provide code for execution by a processor and/or to configure a computer device to use hardware or other components. Other software and hardware components do not need to be aware that the data file is compressed in the flash memory.
    Type: Application
    Filed: March 16, 2017
    Publication date: November 14, 2019
    Inventors: Fumin LU, Yufu LI, Peng WANG, Xiaoguo LIANG, Ye LI
  • Publication number: 20190247474
    Abstract: The present invention is directed to hemostatic compositions comprising at least partially integrated agglomerated ORC fibers, fibrinogen, and thrombin and methods of forming a powdered hemostatic composition, comprising the steps of: forming a suspension of a mixture comprising particles of fibrinogen, thrombin, ORC fibers in a non-aqueous low boiling solvent, agitating and shearing said suspension in a high shear mixing reactor, adding water to allow particles to agglomerate, allowing the non-aqueous solvent to evaporate, drying and sieving the composition; and thus forming the powdered hemostatic composition.
    Type: Application
    Filed: February 13, 2018
    Publication date: August 15, 2019
    Inventors: Shuang Chen, Yufu Li, Aibin Yu, Jianping Yu
  • Patent number: 10278703
    Abstract: The present invention relates to circular anastomosis stapler and kits comprising reinforcing buttress materials and fixation tools that are slidably installed on the anvil shaft of such staplers which provides a temporary mechanical fixation of a reinforcing buttress to the anvil surface of a circular stapler during the insertion of the anvil into the tubular tissue. When the anvil, loaded with the buttress, is in the desired location, the fixation tool is pulled back along the anvil shaft and removed. The shaft is then connected to the stapling head and the stapling is performed. The present invention also relates to methods for using the kits and devices therein.
    Type: Grant
    Filed: March 21, 2016
    Date of Patent: May 7, 2019
    Assignee: Ethicon, Inc.
    Inventors: Nir I. Nativ, Yufu Li, John Matonick, Glenn Cook, Michael Logue
  • Patent number: 10213195
    Abstract: The present invention provides a fixation device that includes an elongate shank defining a longitudinal axis and having at least one engaging member for applying the fixation device within tissue and securing the fixation device in the tissue once implanted formed thereon, and a drive head having a proximal end, a distal end and a radial cross-sectional geometry, where the drive head is mated to the elongate shank, and includes at least one anti-rotational member integral therewith, Fixation device kits utilizing the fixation device, and methods of fixation in tissue are also provided.
    Type: Grant
    Filed: May 11, 2010
    Date of Patent: February 26, 2019
    Assignee: ETHICON, INC.
    Inventors: Joseph H. Contiliano, Yufu Li, Zhigang Li
  • Publication number: 20190008519
    Abstract: The present invention relates to surgical instruments and methods for enhancing properties of tissue repaired or joined by surgical staples and, more particularly to surgical instruments and methods designed to enhance the properties of repaired or adjoined tissue at a target surgical site, especially when sealing an anastomosis between adjacent intestinal sections so as to improve tissue viability, prevent tissue infection, and to prevent leakage.
    Type: Application
    Filed: August 23, 2018
    Publication date: January 10, 2019
    Inventors: Nir I. Nativ, Yufu Li, Michael Logue, Glenn Cook, Gwan-Ywan Lai
  • Publication number: 20180140751
    Abstract: An implantable medical device, which comprises a device substrate, a coating on the substrate which includes a drug, and a protective layer which overlies the coating. The protective layer comprises a polymer selected from the group consisting of polylactic acid, polyglycolic acid and a lactic acid/glycolic acid copolymer having a weight average molecular weight of not more than 40,000.
    Type: Application
    Filed: December 1, 2017
    Publication date: May 24, 2018
    Inventors: Yufu Li, Deborah Schachter, Raymond S. Shissias, Sandra Wechsler
  • Publication number: 20180043054
    Abstract: The present invention is directed to hemostatic compositions comprising at least partially integrated agglomerated ORC fibers, fibrinogen, and thrombin and methods of forming a powdered hemostatic composition, comprising the steps of: forming a suspension of a mixture comprising particles of fibrinogen, thrombin, ORC fibers in a non-aqueous low boiling solvent; spraying the suspension through a nozzle onto a substrate, allowing the non-aqueous solvent to evaporate; separating from the substrate and sieving the composition.
    Type: Application
    Filed: September 7, 2016
    Publication date: February 15, 2018
    Inventors: Shuang Chen, Yufu Li, Dengmin Feng, Xiang Wan
  • Patent number: 9849220
    Abstract: An implantable medical device, which comprises a device substrate, a coating on the substrate which includes a drug which is highly soluble in water, and a protective layer which overlies the coating. The protective layer comprises a polymer selected from the group consisting of polylactic acid, polyglycolic acid and a lactic acid/glycolic acid copolymer having a weight average molecular weight of not more than 40,000.
    Type: Grant
    Filed: October 16, 2009
    Date of Patent: December 26, 2017
    Assignee: DePuy International Limited
    Inventors: Yufu Li, Deborah Schachter, Raymond S. Shissias, Sandra Wechsler
  • Patent number: 9848978
    Abstract: A method of replacing an ACL with a graft. The method provides for the drilling bone tunnels in a femur and a tibia. A replacement graft is provided having first and second ends. A biodegradable composite screw is provided. The screw is made from a biodegradable polymer and a bioceramic or a bioglass. At least one end of the graft is secured in a bone tunnel using the biodegradable composite screw.
    Type: Grant
    Filed: December 3, 2015
    Date of Patent: December 26, 2017
    Assignee: DEPUY MITEK, LLC
    Inventors: Lisa M. Donnelly, Yufu Li, Joan M. Sullivan, Gregory R. Whittaker, J. Jenny Yuan
  • Publication number: 20170281182
    Abstract: The present invention relates to surgical instruments and methods for enhancing properties of tissue repaired or joined by surgical staples and, more particularly to surgical instruments and methods designed to enhance the properties of repaired or adjoined tissue at a target surgical site, especially when sealing an anastomosis between adjacent intestinal sections so as to improve tissue viability, prevent tissue infection, and to prevent leakage.
    Type: Application
    Filed: April 1, 2016
    Publication date: October 5, 2017
    Inventors: Nir I. Nativ, Yufu Li, Michael Logue, Glenn Cook, Gwan-Ywan Lai
  • Publication number: 20170265867
    Abstract: The present invention relates to circular anastomosis stapler and kits comprising reinforcing buttress materials and fixation tools that are slidably installed on the anvil shaft of such staplers which provides a temporary mechanical fixation of a reinforcing buttress to the anvil surface of a circular stapler during the insertion of the anvil into the tubular tissue. When the anvil, loaded with the buttress, is in the desired location, the fixation tool is pulled back along the anvil shaft and removed. The shaft is then connected to the stapling head and the stapling is performed. The present invention also relates to methods for using the kits and devices therein.
    Type: Application
    Filed: March 21, 2016
    Publication date: September 21, 2017
    Inventors: Nir I. Nativ, Yufu Li, John Matonick, Glenn Cook, Michael Logue
  • Publication number: 20160089231
    Abstract: A method of replacing an ACL with a graft. The method provides for the drilling bone tunnels in a femur and a tibia. A replacement graft is provided having first and second ends. A biodegradable composite screw is provided. The screw is made from a biodegradable polymer and a bioceramic or a bioglass. At least one end of the graft is secured in a bone tunnel using the biodegradable composite screw.
    Type: Application
    Filed: December 3, 2015
    Publication date: March 31, 2016
    Inventors: Lisa M. Donnelly, Yufu Li, Joan M. Sullivan, Gregory R. Whittaker, J. Jenny Yuan
  • Patent number: 9226816
    Abstract: A method of replacing an ACL with a graft. The method provides for the drilling bone tunnels in a femur and a tibia. A replacement graft is provided having first and second ends. A biodegradable composite screw is provided. The screw is made from a biodegradable polymer and a bioceramic or a bioglass. At least one end of the graft is secured in a bone tunnel using the biodegradable composite screw.
    Type: Grant
    Filed: September 12, 2014
    Date of Patent: January 5, 2016
    Assignee: DePuy Mitek, LLC
    Inventors: Lisa M. Donnelly, Yufu Li, Joan M. Sullivan, Gregory R. Whittaker, J. Jenny Yuan
  • Patent number: 9210068
    Abstract: Methods and apparatus to improve modification of system routing information in link based systems are described. In one embodiment, entries in a first table (storing data corresponding to routing paths between a plurality of components prior to a hot-plug event) and a second table (storing data corresponding to routing paths between the plurality of components after a hot-plug event) may be compared to determine which corresponding routing registers are to be modified in response to the hot-plug event. Other embodiments are also disclosed.
    Type: Grant
    Filed: November 29, 2007
    Date of Patent: December 8, 2015
    Assignee: Intel Corporation
    Inventors: Xiaohua Cai, Yufu Li
  • Publication number: 20150220134
    Abstract: Methods and apparatus relating to optimizing boot-time peak power consumption for server and/or rack systems are described. In an embodiment, a module execution sequence for a computing device is determined to indicate a sequence of module execution during a boot process of the computing device. The module execution sequence is determined based at least partially on power consumption data and timeline data for each module of the computing device during the boot process of the computing device. Other embodiments are also claimed and described.
    Type: Application
    Filed: September 27, 2013
    Publication date: August 6, 2015
    Inventors: Xiaohu Zhou, Yufu Li
  • Patent number: 9040072
    Abstract: A composite having a poly(ethylene-co-acrylic acid) coupling agent, a filler, and a biocompatible, biodegradable polymer matrix is disclosed. The composites are useful for biomedical applications such as, tissue engineering, drug delivery, and implantable medical devices.
    Type: Grant
    Filed: December 7, 2007
    Date of Patent: May 26, 2015
    Assignee: ETHICON, INC.
    Inventors: Yue Zhou, Kevin Cooper, Yufu Li, Zhigang Li
  • Publication number: 20150121809
    Abstract: A package having an additive that does not adhere to a medical device enclosed therein.
    Type: Application
    Filed: January 12, 2015
    Publication date: May 7, 2015
    Inventors: James M. Peck, Dharmesh Dubey, Michael G. Tokarski, Qiang Zhang, Yufu Li, Steven C. Arnold