Abstract: The present invention discloses a drug recommendation method and system. The method includes: obtaining a drug information set related to a cancer to be treated and a gene set for an individual to be treated; calculating a treatment level of each drug according to side effect information of each drug and gene information targeted by each drug; selecting a drug of the highest treatment level to be added to the selected drug set; deleting a gene corresponding to the drug of the highest treatment level from the gene set; calculating the number of targeted genes of each drug; determining whether a value greater than a preset number value exists in the number of targeted genes, to obtain a determining result; if not, determining a drug in the selected drug set as a recommended drug; and if yes, returning to the treatment level calculating step. The drug recommendation method and system of the present invention provide recommendation of a corresponding drug for a specific disease.