Abstract: The present invention discloses an automatic loading and unloading processing system including: a material storage assembly, which is used to store workpieces; a positioning mechanism which is arranged on a worktable; and a transport mechanism, which is used to transport the workpiece to be processed from on the material storage assembly to on the positioning mechanism and transport the processed workpiece into the material storage assembly, wherein the material storage assembly includes: a material tray; a plurality of fixing bases; a motion mechanism; and a plurality of tooling sub-boards for fixing the workpiece, and the tooling sub-boards are fixed on the fixing base, and the motion mechanism controls the movement of the material tray so that the position of the tooling sub-boards corresponds to the position of the transport mechanism; and the transport mechanism includes: an auxiliary jaw loading and unloading system that is arranged at one support end of the worktable to grab the tooling sub-boards and