Patents by Inventor Yuguang Wang

Yuguang Wang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Xanthine phosphodiesterase V inhibitors
    Publication number: 20040229885
    Abstract: A xanthine phosphodiesterase V inhibitor having the formula (I), with the variables defined herein, which is especially useful for treating male (erectile) and female sexual dysfunction and other physiological disorders: 1
    Type: Application
    Filed: June 9, 2004
    Publication date: November 18, 2004
    Applicant: SCHERING CORPORATION
    Inventors: Samuel Chackalamannil, Yuguang Wang, Craig D. Boyle, Andrew W. Stamford
  • Xanthine phosphodiesterase V inhibitors
    Publication number: 20040167137
    Abstract: A xanthine phosphodiesterase V inhibitor having the formula (I), with the variables defined herein, which is especially useful for treating male (erectile) and female sexual dysfunction and other physiological disorders: 1
    Type: Application
    Filed: February 12, 2004
    Publication date: August 26, 2004
    Inventors: Samuel Chackalamannil, Yuguang Wang, Craig D. Boyle, Andrew W. Stamford
  • Thrombin receptor antagonists
    Publication number: 20030216437
    Abstract: Heterocyclic-substituted tricyclics of the formula 1
    Type: Application
    Filed: April 14, 2003
    Publication date: November 20, 2003
    Applicant: SCHERING CORPORATION
    Inventors: Samuel Chackalamannil, Martin C. Clasby, William J. Greenlee, Yuguang Wang, Yan Xia, Enrico P. Veltri, Mariappan V. Chelliah
  • Muscarinic antagonists
    Publication number: 20030207917
    Abstract: The present invention discloses compounds, which are novel muscarinic receptor antagonists, as well as methods for preparing such compounds. In another embodiment, the invention discloses pharmaceutical compositions comprising such muscarinic receptor antagonists as well as methods for using them to treat cognitive disorders such as Alzheimer's disease.
    Type: Application
    Filed: October 8, 2002
    Publication date: November 6, 2003
    Applicant: Schering Corporation
    Inventors: Yuguang Wang, Samuel Chackalamannil
  • Polycyclic guanine phosphodiesterase V inhibitors
    Publication number: 20030153587
    Abstract: A polycyclic guanine phosphodiesterase V inhibitor having the formula (I.1) or (II.
    Type: Application
    Filed: August 26, 2002
    Publication date: August 14, 2003
    Applicant: Schering Corporation
    Inventors: Theodros Asberom, Yueqing Hu, Dmitri Pissarnitski, Ruo Xu, Yuguang Wang, Samuel Chackalamannil, John W. Clader, Andrew William Stamford
  • Xanthine phosphodiesterase V inhibitors
    Publication number: 20020169174
    Abstract: A xanthine phosphodiesterase V inhibitor having the formula (I), with the variables defined herein, which is especially useful for treating male (erectile) and female sexual dysfunction and other physiological disorders: 1
    Type: Application
    Filed: August 28, 2001
    Publication date: November 14, 2002
    Inventors: Samuel Chackalamannil, Yuguang Wang, Craig D. Boyle, Andrew W. Stamford
  • Muscarinic antagonists
    Patent number: 6043255
    Abstract: Di-N-substituted piperazine or 1,4 di-substituted piperadine compounds in accordance with formula I (including all isomers, salts, esters, and solvates) ##STR1## wherein R, R.sup.1, R.sup.2, R.sup.3, R.sup.4, R.sup.21, R.sup.27, R.sup.28, X, Y, and Z are as defined herein are muscarinic antagonists useful for treating cognitive disorders such as Alzheimer's disease. Pharmaceutical compositions and methods of preparation are also disclosed. Also disclosed are synergistic combinations of compounds of the above formula with acetylcholinesterase inhibitors.
    Type: Grant
    Filed: March 10, 1999
    Date of Patent: March 28, 2000
    Assignee: Schering Corporation
    Inventors: Derek B. Lowe, Wei K. Chang, Joseph A. Kozlowski, Joel G. Berger, Robert McQuade, Allen Barnett, Margaret Sherlock, Wing Tom, Sundeep Dugar, Lian-Yong Chen, John W Clader, Samuel Chackalamannil, Yuguang Wang, Stuart W. McCombie, Jayaram R. Tagat, Susan F. Vice, Wayne Vaccaro, Michael J. Green, Margaret E. Browne, Theodros Asberom, Craig D. Boyle
  • Ether muscarinic antagonists
    Patent number: 5977138
    Abstract: 1,4 Di-substituted piperidine muscarinic antagonists of formula I ##STR1## or an isomer, pharmaceutically acceptable salt, ester or solvate thereof, whereinX is a bond, --O--, --S--, --SO--, --SO.sub.2 --, --CO--, --C(OR.sup.7).sub.2 --, --CH.sub.2 --O--, --O-- CH.sub.2 --, --CH.dbd.CH--, --CH.sub.2 --, --CH(C.sub.1 -C.sub.6 alkyl)-, --C(C.sub.1 -C.sub.6 alkyl).sub.2 --, --CONR.sup.17 --, --NR.sup.17 CO--, --O--C(O)NR.sup.17 --, --NR.sup.17 C(O)--O--, --SO.sub.2 NR.sup.17 -- or --NR.sup.17 SO.sub.2 --;R is cycloalkyl, optionally substituted phenyl or optionally substituted pyridyl;R.sup.2 is H, alkyl, optionally substituted cycloalkyl, cycloalkenyl, t-butoxycarbonyl or optionally substituted piperidinyl; and the remaining variables are as defined in the specification, are disclosed. Compounds of formula I are useful for treating cognitive disorders such as Alzheimer's disease.
    Type: Grant
    Filed: August 13, 1997
    Date of Patent: November 2, 1999
    Assignee: Schering Corporation
    Inventors: Yuguang Wang, Wei K. Chang, Sundeep Dugar, Samuel Chackalamannil
  • Muscarinic antagonists
    Patent number: 5889006
    Abstract: Di-N-substituted piperazine or 1,4 di-substituted piperadine compounds in accordance with formula I (including all isomers, salts, esters, and solvates) ##STR1## wherein R, R.sup.1, R.sup.2, R.sup.3, R.sup.4, R.sup.21, R.sup.27, R.sup.28, X, Y, and Z are as defined herein are muscarinic antagonists useful for treating cognitive disorders such as Alzheimer's disease. Pharmaceutical compositions and methods of preparation are also disclosed. Also disclosed are synergistic combinations of compounds of the above formula with acetylcholinesterase inhibitors.
    Type: Grant
    Filed: August 8, 1996
    Date of Patent: March 30, 1999
    Assignee: Schering Corporation
    Inventors: Derek B. Lowe, Wei K. Chang, Joseph A. Kozlowski, Joel G. Berger, Robert McQuade, Allen Barnett, Margaret Sherlock, Wing Tom, Sundeep Dugar, Lian-Yong Chen, John W. Clader, Samuel Chackalamannil, Yuguang Wang, Stuart W. McCombie, Jayaram R. Tagat, Susan F. Vice, Wayne Vaccaro, Michael J. Green, Margaret E. Browne, Theodros Asberom, Craig D. Boyle