Patents by Inventor Yuguo Du

Yuguo Du has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • SYNTHESIS OF TIMOSAPONIN BII
    Publication number: 20110054156
    Abstract: The invention provides a synthetic route from sarsasapogenin to timosaponin BII and related compounds. A diketone intermediate is provided, which can advantageously be used for in situ assembly of complex sugar moieties of the desired glycone end product. The diketone compound is then selectively reduced using a borohydride reducing agent to form the desired end product, certain of the end products and intermediates are novel compounds perse.
    Type: Application
    Filed: April 30, 2008
    Publication date: March 3, 2011
    Applicant: INSTITUTE OF RADIATION MEDICINE, ACADEMY OF MILITARY SCIENCES, PLA
    Inventors: Shuihong Cheng, Yuguo Du, Baiping Ma, Lu Li, Yang Zhao
  • Method for synthesizing C-glycosides of ulosonic acids
    Patent number: 6590110
    Abstract: The invention is directed to a method for synthesizing C-glycosides of ulosonic acids, as well as intermediates thereof and C-glycosides prepared by this method.
    Type: Grant
    Filed: May 17, 2001
    Date of Patent: July 8, 2003
    Assignee: University of Iowa Research Foundation
    Inventors: Robert J. Linhardt, Tulay Polat, Yuguo Du
  • C-glycoside analogs and methods for their preparation and use
    Patent number: 6245902
    Abstract: The invention provides versatile sialic acid C-glycoside precursors that are useful for preparing C-glycoside analogs of Gangliosides, peptides, and proteins, as well as synthetic intermediates useful for the preparation of the precursors, and synthetic methods useful for preparing the precursors and the intermediates. The invention also provides gangliosides, peptides, and proteins that comprise sialic acid C-glycoside components, as well as synthetic methods useful for the preparation of such compounds.
    Type: Grant
    Filed: August 9, 1999
    Date of Patent: June 12, 2001
    Assignee: University of Iowa Research Foundation
    Inventors: Robert J. Linhardt, Helene G. Bazin, Yuguo Du, Tulay Polat