Patents by Inventor Yuguo Lei

Yuguo Lei has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • DISSOLVABLE AND DEGRADABLE ARTIFICIAL CIRCULATION SYSTEMS FOR LARGE VOLUME TISSUES
    Publication number: 20220275342
    Abstract: Embodiments of the disclosure provide a dissolvable or degradable artificial circulation system for engineering, culturing, and integrating large volume tissues. Also provided are methods of using large engineered tissues prepared using the degradable artificial circulation system for clinical applications and for various applications such as large-scale production of therapeutic or consumable products, drug discovery, and toxicity screening.
    Type: Application
    Filed: July 6, 2020
    Publication date: September 1, 2022
    Inventors: Yuguo LEI, Qiang LI, Ou WANG
  • LARGE SCALE CELL MANUFACTURE SYSTEM
    Publication number: 20220145227
    Abstract: Methods of culturing and manufacturing of cells on a large-scale level are disclosed. Particularly, a manufacturing system and device, and methods of using the system and device for culturing and manufacturing cells in hollow fibers made from alginate polymers are provided.
    Type: Application
    Filed: November 12, 2021
    Publication date: May 12, 2022
    Inventor: Yuguo Lei
  • Thermoreversible polymers and methods of use thereof
    Patent number: 10982055
    Abstract: The present disclosure provides thermoreversible polymers, hydrogel compositions comprising the thermoreversible polymers, as well as methods of making and using the thermoreversible polymers.
    Type: Grant
    Filed: October 4, 2016
    Date of Patent: April 20, 2021
    Assignee: The Regents of the University of California
    Inventors: Christina Marie Fuentes, Barbara L. Ekerdt, David V. Schaffer, Rachel Segalman, Yuguo Lei
  • CELL EXPANSION SYSTEM
    Publication number: 20210017485
    Abstract: A cell expansion system for culturing and expanding cells in hydrogel tubes is disclosed herein. The cell expansion system allows for expanding cells that can significantly reduce the production time and cost, while increase the production capacity.
    Type: Application
    Filed: March 15, 2019
    Publication date: January 21, 2021
    Inventors: Yuguo Lei, Hendrik Viljoen
  • PERSONALIZED CELLULAR BIOMANUFACTURING WITH A CLOSED, MINIATURE CELL CULTURE SYSTEM
    Publication number: 20190376016
    Abstract: Closed, miniature devices and methods of using the devices for culturing cells are disclosed. Particularly, a device, and methods of using the device for manufacturing, expanding, differentiating and/or reprogramming cells for personalized medicine, such to allow for conducting medical procedures at the point-of-care, are provided.
    Type: Application
    Filed: November 22, 2017
    Publication date: December 12, 2019
    Inventor: Yuguo Lei
  • LARGE SCALE CELL MANUFACTURE SYSTEM
    Publication number: 20180327703
    Abstract: Methods of culturing and manufacturing of cells on a large-scale level are disclosed. Particularly, a manufacturing system and device, and methods of using the system and device for culturing and manufacturing cells in hollow fibers made from alginate polymers are provided.
    Type: Application
    Filed: November 23, 2016
    Publication date: November 15, 2018
    Inventor: Yuguo Lei
  • THERMOREVERSIBLE POLYMERS AND METHODS OF USE THEREOF
    Publication number: 20180244859
    Abstract: The present disclosure provides thermoreversible polymers, hydrogel compositions comprising the thermoreversible polymers, as well as methods of making and using the thermoreversible polymers.
    Type: Application
    Filed: October 4, 2016
    Publication date: August 30, 2018
    Inventors: Christina Marie Fuentes, Barbara L. Ekerdt, David V. Schaffer, Rachel Segalman, Yuguo Lei