Patents by Inventor Yuh-Jiuan Lin
Yuh-Jiuan Lin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20150184149Abstract: A method for isolating nucleic acids is provided. The method includes providing a biological sample containing at least one nucleic acid, and mixing the biological sample with an isolating agent under a suitable condition to isolate the nucleic acids from the biological sample in single step, wherein the isolating agent contains 1-40 wt % of PEG and/or more than 30 wt % of low molecular weight alcohol, a salt, and a detergent. Isolated nucleic acids are bound to a solid support by changes in the solubility of nucleic acids. Additionally, the present invention further provides an isolating agent and kit for isolating nucleic acids.Type: ApplicationFiled: March 11, 2015Publication date: July 2, 2015Applicant: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTEInventors: Pei-Shin JIANG, Kun-Chan WU, Yu-Ting SU, Chia-Yun LIN, Siou-Cing SU, Yuh-Jiuan LIN
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Patent number: 9006419Abstract: A method for isolating nucleic acids is provided. The method includes providing a biological sample containing at least one nucleic acid, and mixing the biological sample with an isolating agent under a suitable condition to isolate the nucleic acids from the biological sample in single step, wherein the isolating agent contains 1-40 wt % of PEG and/or more than 30 wt % of low molecular weight alcohol, a salt, and a detergent. Isolated nucleic acids are bound to a solid support by changes in the solubility of nucleic acids. Additionally, the present invention further provides an isolating agent and kit for isolating nucleic acids.Type: GrantFiled: October 15, 2010Date of Patent: April 14, 2015Assignee: Industrial Technology Research InstituteInventors: Pei-Shin Jiang, Kun-Chan Wu, Yu-Ting Su, Chia-Yun Lin, Siou-Cing Su, Yuh-Jiuan Lin
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Patent number: 8956580Abstract: An analysis cartridge comprising a cartridge body, a first cover, a liquid storage box and a sealing film is disclosed. The cartridge body has an accommodation portion and a first side and a second side opposite to the first side. The first cover covers the first side or the second side of the cartridge body and has a first through hole. The liquid storage box is disposed in the accommodation portion and has a liquid through hole. The sealing film seals the liquid through hole of the said liquid storage box and passes through the first through hole of the first cover, wherein the liquid through hole is exposed by removing the sealing film.Type: GrantFiled: January 14, 2013Date of Patent: February 17, 2015Assignee: Lite-On Technology CorporationInventors: Cheng-Chang Lai, Fu-Chun Huang, Yuh-Jiuan Lin
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Patent number: 8883095Abstract: An analysis cartridge and an analysis system thereof are disclosed. The analysis cartridge comprises a cartridge body, a liquid storage box and a sealing film. The cartridge body has an accommodation portion. The liquid storage box is disposed within the accommodation portion and has a liquid storage tank and a pillar receiving hole. The sealing film covers the pillar receiving hole and seals an opening of the liquid storage tank.Type: GrantFiled: January 14, 2013Date of Patent: November 11, 2014Assignee: Lite-On Technology CorporationInventors: Cheng-Chang Lai, Fu-Chun Huang, Yuh-Jiuan Lin, Timothy Z. Liu
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Publication number: 20130309133Abstract: An analysis cartridge and an analysis system thereof are disclosed. The analysis cartridge comprises a cartridge body, a liquid storage box and a sealing film. The cartridge body has an accommodation portion. The liquid storage box is disposed within the accommodation portion and has a liquid storage tank and a pillar receiving hole. The sealing film covers the pillar receiving hole and seals an opening of the liquid storage tank.Type: ApplicationFiled: January 14, 2013Publication date: November 21, 2013Applicant: LITE-ON IT CORPORATIONInventors: Cheng-Chang LAI, Fu-Chun HUANG, Yuh-Jiuan LIN, Timothy Z. LIU
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Publication number: 20130309149Abstract: An analysis cartridge comprising a cartridge body, a first cover, a liquid storage box and a sealing film is disclosed. The cartridge body has an accommodation portion and a first side and a second side opposite to the first side. The first cover covers the first side or the second side of the cartridge body and has a first through hole. The liquid storage box is disposed in the accommodation portion and has a liquid through hole. The sealing film seals the liquid through hole of the said liquid storage box and passes through the first through hole of the first cover, wherein the liquid through hole is exposed by removing the sealing film.Type: ApplicationFiled: January 14, 2013Publication date: November 21, 2013Applicant: LITE-ON IT CORPORATIONInventors: Cheng-Chang LAI, Fu-Chun HUANG, Yuh-Jiuan LIN
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Patent number: 8513405Abstract: Disclosed are a chaotropic agent; a reagent including a chaotropic agent and a lithium salt; a reagent kit including a chaotropic agent; a chaotropic agent, a reagent, a reagent kit, and a method for isolating a nucleic acid by use of a magnetic cellulose material; a method for binding a nucleic acid to a magnetic cellulose material; a method for isolating a nucleic acid; and a method for purifying a chromosome DNA. It is required that each of the chaotropic agents, the reagents, and the reagent kits works with at least one solid-phase, magnetic cellulose-containing carrier to isolate a nucleic acid from non-nucleic acid substances. In addition, each chaotropic agent includes an alcohol substance and a substrate solution for adjusting the alcohol substance to an appropriate concentration and thereby promoting binding of the nucleic acid in a sample to the magnetic cellulose.Type: GrantFiled: April 2, 2008Date of Patent: August 20, 2013Assignee: RBC Bioscience Corp.Inventors: Pei-Shin Jiang, Yu-Ting Su, Kun-Chan Wu, Hui-Ju Cho, Wen-Hsun Kuo, Yuh-Jiuan Lin, Yi-Ling Li, Cheng-Chun Kuan
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Patent number: 8415170Abstract: The invention provides a method for continuously detecting glucose concentration in a sample, including: (a) providing a biosensor comprising a transducer and a polysaccharide covered on the surface of the transducer; (b) providing a carbohydrate binding protein solution, wherein the carbohydrate binding protein has at least one receptor, and the receptor is capable of binding to the polysaccharide and glucose; (c) mixing a sample and the carbohydrate binding protein solution to form a mixture; (d) contacting the mixture with the biosensor; (e) detecting the amount of carbohydrate binding proteins bound to the polysaccharide by the biosensor, wherein glucose concentration of the sample is inversely proportional to the amount of carbohydrate binding proteins bound to the polysaccharide; and (f) refreshing the surface of the biosensor with a high concentration glucose solution.Type: GrantFiled: March 4, 2010Date of Patent: April 9, 2013Assignee: Industrial Technology Research InstituteInventors: Kun-Feng Lee, Chien-An Chen, Hong-Wen Chang, Yuh-Jiuan Lin
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Patent number: 8216826Abstract: A fluid analyzing apparatus. The fluid analyzing apparatus sequentially or simultaneously detects and analyzes a multiplex fluid sample with suitable analyzing elements. Meanwhile, the fluid analyzing apparatus may be disassembled to a first unit, a second unit and a third unit, such that the analyzing elements therein are easily disposed and replaced. The fluid analyzing apparatus analyzes and detects the multiplex fluid sample by allowing the multiplex fluid sample to sequentially or simultaneously flow through a plurality of target chambers. The fluid analyzing apparatus sequentially or simultaneously transports the multiplex fluid sample to the target chambers, thereby enhancing the speed and analysis thereof.Type: GrantFiled: October 14, 2008Date of Patent: July 10, 2012Assignee: Industrial Technology Research InstituteInventors: Kun Feng Lee, Pei-Shin Jiang, Yuh-Jiuan Lin
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Publication number: 20120107246Abstract: Methotrexate-modified nanoparticles that target tumors, compositions that include the nanoparticles, methods of imaging tissues using the nanoparticles, and methods for treating tissues using the nanoparticles.Type: ApplicationFiled: June 18, 2010Publication date: May 3, 2012Applicant: WASHINGTON, UNIVERSITY OFInventors: Miqin Zhang, Shian-Jy Wang, Nathan Kohler, Yuh-Jiuan Lin, Conroy Sun
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Publication number: 20110166338Abstract: Disclosed are a chaotropic agent; a reagent including a chaotropic agent and a lithium salt; a reagent kit including a chaotropic agent; a chaotropic agent, a reagent, a reagent kit, and a method for isolating a nucleic acid by use of a magnetic cellulose material; a method for binding a nucleic acid to a magnetic cellulose material; a method for isolating a nucleic acid; and a method for purifying a chromosome DNA. It is required that each of the chaotropic agents, the reagents, and the reagent kits works with at least one solid-phase, magnetic cellulose-containing carrier to isolate a nucleic acid from non-nucleic acid substances. In addition, each chaotropic agent includes an alcohol substance and a substrate solution for adjusting the alcohol substance to an appropriate concentration and thereby promoting binding of the nucleic acid in a sample to the magnetic cellulose.Type: ApplicationFiled: April 2, 2008Publication date: July 7, 2011Inventors: Pei-Shin Jiang, Yu-Ting Su, Kun-Chan Wu, Hui-Ju Cho, Wen-Hsun Kuo, Yuh-Jiuan Lin, Yi-Ling Li, Cheng-Chun Kuan
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Publication number: 20110097782Abstract: A method for isolating nucleic acids is provided. The method includes providing a biological sample containing at least one nucleic acid, and mixing the biological sample with an isolating agent under a suitable condition to isolate the nucleic acids from the biological sample in single step, wherein the isolating agent contains 1-40 wt % of PEG and/or more than 30 wt % of low molecular weight alcohol, a salt, and a detergent. Isolated nucleic acids are bound to a solid support by changes in the solubility of nucleic acids. Additionally, the present invention further provides an isolating agent and kit for isolating nucleic acids.Type: ApplicationFiled: October 15, 2010Publication date: April 28, 2011Applicant: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTEInventors: Pei-Shin JIANG, Kun-Chan Wu, Yu-Ting Su, Chia-Yun Lin, Siou-Cing Su, Yuh-Jiuan Lin
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Publication number: 20100304399Abstract: The invention provides a method for continuously detecting glucose concentration in a sample, including: (a) providing a biosensor comprising a transducer and a polysaccharide covered on the surface of the transducer; (b) providing a carbohydrate binding protein solution, wherein the carbohydrate binding protein has at least one receptor, and the receptor is capable of binding to the polysaccharide and glucose; (c) mixing a sample and the carbohydrate binding protein solution to form a mixture; (d) contacting the mixture with the biosensor; (e) detecting the amount of carbohydrate binding proteins bound to the polysaccharide by the biosensor, wherein glucose concentration of the sample is inversely proportional to the amount of carbohydrate binding proteins bound to the polysaccharide; and (f) refreshing the surface of the biosensor with a high concentration glucose solution.Type: ApplicationFiled: March 4, 2010Publication date: December 2, 2010Applicant: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTEInventors: Kun-Feng Lee, Chien-An Chen, Hong-Wen Chang, Yuh-Jiuan Lin
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Patent number: 7829026Abstract: A magnetic separation device, comprising: at least a test tube base, for receiving at least a test tube; and a magnetic member, pivotally connected to the at least one test tube base and capable of generating a magnetic force. With the aforesaid device, the test tube being received in the test tube base can be moved toward/away from the magnetic member while the magnetic member and the test tube base are driven to rotate about a pivotal end connecting the two, and thereby, the strength of the magnetic force applied on a mixture containing in the test tube by the magnetic member is varied accordingly.Type: GrantFiled: January 24, 2008Date of Patent: November 9, 2010Assignee: Industrial Technology Research InstituteInventors: Chih-Hsien Su, Chao-Hung Kao, Yuh-Jiuan Lin
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Patent number: 7763169Abstract: A magnetic separation device, comprising: a separator, including a top base and a bottom base; at least a groove set, each composed of two arc-like grooves having curvatures opposite to each other; at least a magnetic member, being movably fitted inside the two arc-like grooves of the at least one groove set; and at least a test tube slot, each being formed at the outer rim of a base selected from the group consisting of the top and the bottom base of the separator; wherein the top and the bottom bases are assembled by means of a pivotal axis piecing through about at the center of the top and the bottom bases for enabling the two bases to rotate relative to each other; and one of the two arc-like groove is formed on the top base at a surface thereof facing toward the bottom base while forming another arc-like groove on the bottom base at a surface thereof facing toward the top base.Type: GrantFiled: January 15, 2008Date of Patent: July 27, 2010Assignee: Industrial Technology Research InstituteInventors: Chih-Hsien Su, Chao-Hung Kao, Yuh-Jiuan Lin
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Patent number: 7740759Abstract: A magnetic separation device separating magnetic material from a working fluid of a container is disclosed. The magnetic separation device includes a first element, a second element and a magnetic assembly structure including a plurality of magnetic units. The first element includes a first body, a plurality of first main positioning portions disposed on the first body, and a plurality of first sub-positioning portions disposed on the first body and next to the first main positioning portions to receive the container. The second element includes a second body, a plurality of second main positioning portions disposed on the second body, and a plurality of second sub-positioning portions disposed on the second body and next to the second main positioning portions to receive the container. The magnetic units disposed on the first main positioning portions and the second main positioning portions absorb magnetic material from the working fluid.Type: GrantFiled: April 17, 2007Date of Patent: June 22, 2010Assignee: Industrial Technology Research InstituteInventors: Chih Hsien Su, Hsiao Cheng Lin, Chi-Min Chau, Yuh-Jiuan Lin, Wen-Hsun Kuo
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Patent number: 7700193Abstract: A core-shell structure with magnetic, thermal, and optical characteristics. The optical absorption band is tailorable by choice of the mixing ratio of the core/shell component to give the desired shell thickness. The core-shell structure is particularly suitable for biomedical applications such as MRI (magnetic resonance imaging) developer, specific tissue identification developer, and magnetic thermal therapy.Type: GrantFiled: September 29, 2005Date of Patent: April 20, 2010Assignee: Industrial Technology Research InstituteInventors: Ming-Yao Chen, Wen-Hsiang Chang, Chin-I Lin, Shian-Jy Jassy Wang, Yuh-Jiuan Lin
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Patent number: D602387Type: GrantFiled: November 14, 2008Date of Patent: October 20, 2009Assignee: Industrial Technology Research InstituteInventors: Jhao-Syong Chen, Kun Feng Lee, Yu-Jin Kao, Chih Hsien Su, Yi-Shang Lin, Yuh-Jiuan Lin
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Patent number: D634839Type: GrantFiled: August 30, 2006Date of Patent: March 22, 2011Assignee: Industrial Technology Research InstituteInventors: Yuh-Jiuan Lin, Hsi-Feng Kao, Kun-Feng Lee, Chung-Kai Chen
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Patent number: D640367Type: GrantFiled: August 30, 2006Date of Patent: June 21, 2011Assignee: Industrial Technology Research InstituteInventors: Yuh-Jiuan Lin, Kun-Feng Lee, Hsi-Feng Kao, Hsing-Hsien Ho