Patents by Inventor Yuh-Jiuan Lin

Yuh-Jiuan Lin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20150184149
    Abstract: A method for isolating nucleic acids is provided. The method includes providing a biological sample containing at least one nucleic acid, and mixing the biological sample with an isolating agent under a suitable condition to isolate the nucleic acids from the biological sample in single step, wherein the isolating agent contains 1-40 wt % of PEG and/or more than 30 wt % of low molecular weight alcohol, a salt, and a detergent. Isolated nucleic acids are bound to a solid support by changes in the solubility of nucleic acids. Additionally, the present invention further provides an isolating agent and kit for isolating nucleic acids.
    Type: Application
    Filed: March 11, 2015
    Publication date: July 2, 2015
    Applicant: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE
    Inventors: Pei-Shin JIANG, Kun-Chan WU, Yu-Ting SU, Chia-Yun LIN, Siou-Cing SU, Yuh-Jiuan LIN
  • Patent number: 9006419
    Abstract: A method for isolating nucleic acids is provided. The method includes providing a biological sample containing at least one nucleic acid, and mixing the biological sample with an isolating agent under a suitable condition to isolate the nucleic acids from the biological sample in single step, wherein the isolating agent contains 1-40 wt % of PEG and/or more than 30 wt % of low molecular weight alcohol, a salt, and a detergent. Isolated nucleic acids are bound to a solid support by changes in the solubility of nucleic acids. Additionally, the present invention further provides an isolating agent and kit for isolating nucleic acids.
    Type: Grant
    Filed: October 15, 2010
    Date of Patent: April 14, 2015
    Assignee: Industrial Technology Research Institute
    Inventors: Pei-Shin Jiang, Kun-Chan Wu, Yu-Ting Su, Chia-Yun Lin, Siou-Cing Su, Yuh-Jiuan Lin
  • Patent number: 8956580
    Abstract: An analysis cartridge comprising a cartridge body, a first cover, a liquid storage box and a sealing film is disclosed. The cartridge body has an accommodation portion and a first side and a second side opposite to the first side. The first cover covers the first side or the second side of the cartridge body and has a first through hole. The liquid storage box is disposed in the accommodation portion and has a liquid through hole. The sealing film seals the liquid through hole of the said liquid storage box and passes through the first through hole of the first cover, wherein the liquid through hole is exposed by removing the sealing film.
    Type: Grant
    Filed: January 14, 2013
    Date of Patent: February 17, 2015
    Assignee: Lite-On Technology Corporation
    Inventors: Cheng-Chang Lai, Fu-Chun Huang, Yuh-Jiuan Lin
  • Patent number: 8883095
    Abstract: An analysis cartridge and an analysis system thereof are disclosed. The analysis cartridge comprises a cartridge body, a liquid storage box and a sealing film. The cartridge body has an accommodation portion. The liquid storage box is disposed within the accommodation portion and has a liquid storage tank and a pillar receiving hole. The sealing film covers the pillar receiving hole and seals an opening of the liquid storage tank.
    Type: Grant
    Filed: January 14, 2013
    Date of Patent: November 11, 2014
    Assignee: Lite-On Technology Corporation
    Inventors: Cheng-Chang Lai, Fu-Chun Huang, Yuh-Jiuan Lin, Timothy Z. Liu
  • Publication number: 20130309133
    Abstract: An analysis cartridge and an analysis system thereof are disclosed. The analysis cartridge comprises a cartridge body, a liquid storage box and a sealing film. The cartridge body has an accommodation portion. The liquid storage box is disposed within the accommodation portion and has a liquid storage tank and a pillar receiving hole. The sealing film covers the pillar receiving hole and seals an opening of the liquid storage tank.
    Type: Application
    Filed: January 14, 2013
    Publication date: November 21, 2013
    Applicant: LITE-ON IT CORPORATION
    Inventors: Cheng-Chang LAI, Fu-Chun HUANG, Yuh-Jiuan LIN, Timothy Z. LIU
  • Publication number: 20130309149
    Abstract: An analysis cartridge comprising a cartridge body, a first cover, a liquid storage box and a sealing film is disclosed. The cartridge body has an accommodation portion and a first side and a second side opposite to the first side. The first cover covers the first side or the second side of the cartridge body and has a first through hole. The liquid storage box is disposed in the accommodation portion and has a liquid through hole. The sealing film seals the liquid through hole of the said liquid storage box and passes through the first through hole of the first cover, wherein the liquid through hole is exposed by removing the sealing film.
    Type: Application
    Filed: January 14, 2013
    Publication date: November 21, 2013
    Applicant: LITE-ON IT CORPORATION
    Inventors: Cheng-Chang LAI, Fu-Chun HUANG, Yuh-Jiuan LIN
  • Patent number: 8513405
    Abstract: Disclosed are a chaotropic agent; a reagent including a chaotropic agent and a lithium salt; a reagent kit including a chaotropic agent; a chaotropic agent, a reagent, a reagent kit, and a method for isolating a nucleic acid by use of a magnetic cellulose material; a method for binding a nucleic acid to a magnetic cellulose material; a method for isolating a nucleic acid; and a method for purifying a chromosome DNA. It is required that each of the chaotropic agents, the reagents, and the reagent kits works with at least one solid-phase, magnetic cellulose-containing carrier to isolate a nucleic acid from non-nucleic acid substances. In addition, each chaotropic agent includes an alcohol substance and a substrate solution for adjusting the alcohol substance to an appropriate concentration and thereby promoting binding of the nucleic acid in a sample to the magnetic cellulose.
    Type: Grant
    Filed: April 2, 2008
    Date of Patent: August 20, 2013
    Assignee: RBC Bioscience Corp.
    Inventors: Pei-Shin Jiang, Yu-Ting Su, Kun-Chan Wu, Hui-Ju Cho, Wen-Hsun Kuo, Yuh-Jiuan Lin, Yi-Ling Li, Cheng-Chun Kuan
  • Patent number: 8415170
    Abstract: The invention provides a method for continuously detecting glucose concentration in a sample, including: (a) providing a biosensor comprising a transducer and a polysaccharide covered on the surface of the transducer; (b) providing a carbohydrate binding protein solution, wherein the carbohydrate binding protein has at least one receptor, and the receptor is capable of binding to the polysaccharide and glucose; (c) mixing a sample and the carbohydrate binding protein solution to form a mixture; (d) contacting the mixture with the biosensor; (e) detecting the amount of carbohydrate binding proteins bound to the polysaccharide by the biosensor, wherein glucose concentration of the sample is inversely proportional to the amount of carbohydrate binding proteins bound to the polysaccharide; and (f) refreshing the surface of the biosensor with a high concentration glucose solution.
    Type: Grant
    Filed: March 4, 2010
    Date of Patent: April 9, 2013
    Assignee: Industrial Technology Research Institute
    Inventors: Kun-Feng Lee, Chien-An Chen, Hong-Wen Chang, Yuh-Jiuan Lin
  • Patent number: 8216826
    Abstract: A fluid analyzing apparatus. The fluid analyzing apparatus sequentially or simultaneously detects and analyzes a multiplex fluid sample with suitable analyzing elements. Meanwhile, the fluid analyzing apparatus may be disassembled to a first unit, a second unit and a third unit, such that the analyzing elements therein are easily disposed and replaced. The fluid analyzing apparatus analyzes and detects the multiplex fluid sample by allowing the multiplex fluid sample to sequentially or simultaneously flow through a plurality of target chambers. The fluid analyzing apparatus sequentially or simultaneously transports the multiplex fluid sample to the target chambers, thereby enhancing the speed and analysis thereof.
    Type: Grant
    Filed: October 14, 2008
    Date of Patent: July 10, 2012
    Assignee: Industrial Technology Research Institute
    Inventors: Kun Feng Lee, Pei-Shin Jiang, Yuh-Jiuan Lin
  • Publication number: 20120107246
    Abstract: Methotrexate-modified nanoparticles that target tumors, compositions that include the nanoparticles, methods of imaging tissues using the nanoparticles, and methods for treating tissues using the nanoparticles.
    Type: Application
    Filed: June 18, 2010
    Publication date: May 3, 2012
    Applicant: WASHINGTON, UNIVERSITY OF
    Inventors: Miqin Zhang, Shian-Jy Wang, Nathan Kohler, Yuh-Jiuan Lin, Conroy Sun
  • Publication number: 20110166338
    Abstract: Disclosed are a chaotropic agent; a reagent including a chaotropic agent and a lithium salt; a reagent kit including a chaotropic agent; a chaotropic agent, a reagent, a reagent kit, and a method for isolating a nucleic acid by use of a magnetic cellulose material; a method for binding a nucleic acid to a magnetic cellulose material; a method for isolating a nucleic acid; and a method for purifying a chromosome DNA. It is required that each of the chaotropic agents, the reagents, and the reagent kits works with at least one solid-phase, magnetic cellulose-containing carrier to isolate a nucleic acid from non-nucleic acid substances. In addition, each chaotropic agent includes an alcohol substance and a substrate solution for adjusting the alcohol substance to an appropriate concentration and thereby promoting binding of the nucleic acid in a sample to the magnetic cellulose.
    Type: Application
    Filed: April 2, 2008
    Publication date: July 7, 2011
    Inventors: Pei-Shin Jiang, Yu-Ting Su, Kun-Chan Wu, Hui-Ju Cho, Wen-Hsun Kuo, Yuh-Jiuan Lin, Yi-Ling Li, Cheng-Chun Kuan
  • Publication number: 20110097782
    Abstract: A method for isolating nucleic acids is provided. The method includes providing a biological sample containing at least one nucleic acid, and mixing the biological sample with an isolating agent under a suitable condition to isolate the nucleic acids from the biological sample in single step, wherein the isolating agent contains 1-40 wt % of PEG and/or more than 30 wt % of low molecular weight alcohol, a salt, and a detergent. Isolated nucleic acids are bound to a solid support by changes in the solubility of nucleic acids. Additionally, the present invention further provides an isolating agent and kit for isolating nucleic acids.
    Type: Application
    Filed: October 15, 2010
    Publication date: April 28, 2011
    Applicant: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE
    Inventors: Pei-Shin JIANG, Kun-Chan Wu, Yu-Ting Su, Chia-Yun Lin, Siou-Cing Su, Yuh-Jiuan Lin
  • Publication number: 20100304399
    Abstract: The invention provides a method for continuously detecting glucose concentration in a sample, including: (a) providing a biosensor comprising a transducer and a polysaccharide covered on the surface of the transducer; (b) providing a carbohydrate binding protein solution, wherein the carbohydrate binding protein has at least one receptor, and the receptor is capable of binding to the polysaccharide and glucose; (c) mixing a sample and the carbohydrate binding protein solution to form a mixture; (d) contacting the mixture with the biosensor; (e) detecting the amount of carbohydrate binding proteins bound to the polysaccharide by the biosensor, wherein glucose concentration of the sample is inversely proportional to the amount of carbohydrate binding proteins bound to the polysaccharide; and (f) refreshing the surface of the biosensor with a high concentration glucose solution.
    Type: Application
    Filed: March 4, 2010
    Publication date: December 2, 2010
    Applicant: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE
    Inventors: Kun-Feng Lee, Chien-An Chen, Hong-Wen Chang, Yuh-Jiuan Lin
  • Patent number: 7829026
    Abstract: A magnetic separation device, comprising: at least a test tube base, for receiving at least a test tube; and a magnetic member, pivotally connected to the at least one test tube base and capable of generating a magnetic force. With the aforesaid device, the test tube being received in the test tube base can be moved toward/away from the magnetic member while the magnetic member and the test tube base are driven to rotate about a pivotal end connecting the two, and thereby, the strength of the magnetic force applied on a mixture containing in the test tube by the magnetic member is varied accordingly.
    Type: Grant
    Filed: January 24, 2008
    Date of Patent: November 9, 2010
    Assignee: Industrial Technology Research Institute
    Inventors: Chih-Hsien Su, Chao-Hung Kao, Yuh-Jiuan Lin
  • Patent number: 7763169
    Abstract: A magnetic separation device, comprising: a separator, including a top base and a bottom base; at least a groove set, each composed of two arc-like grooves having curvatures opposite to each other; at least a magnetic member, being movably fitted inside the two arc-like grooves of the at least one groove set; and at least a test tube slot, each being formed at the outer rim of a base selected from the group consisting of the top and the bottom base of the separator; wherein the top and the bottom bases are assembled by means of a pivotal axis piecing through about at the center of the top and the bottom bases for enabling the two bases to rotate relative to each other; and one of the two arc-like groove is formed on the top base at a surface thereof facing toward the bottom base while forming another arc-like groove on the bottom base at a surface thereof facing toward the top base.
    Type: Grant
    Filed: January 15, 2008
    Date of Patent: July 27, 2010
    Assignee: Industrial Technology Research Institute
    Inventors: Chih-Hsien Su, Chao-Hung Kao, Yuh-Jiuan Lin
  • Patent number: 7740759
    Abstract: A magnetic separation device separating magnetic material from a working fluid of a container is disclosed. The magnetic separation device includes a first element, a second element and a magnetic assembly structure including a plurality of magnetic units. The first element includes a first body, a plurality of first main positioning portions disposed on the first body, and a plurality of first sub-positioning portions disposed on the first body and next to the first main positioning portions to receive the container. The second element includes a second body, a plurality of second main positioning portions disposed on the second body, and a plurality of second sub-positioning portions disposed on the second body and next to the second main positioning portions to receive the container. The magnetic units disposed on the first main positioning portions and the second main positioning portions absorb magnetic material from the working fluid.
    Type: Grant
    Filed: April 17, 2007
    Date of Patent: June 22, 2010
    Assignee: Industrial Technology Research Institute
    Inventors: Chih Hsien Su, Hsiao Cheng Lin, Chi-Min Chau, Yuh-Jiuan Lin, Wen-Hsun Kuo
  • Patent number: 7700193
    Abstract: A core-shell structure with magnetic, thermal, and optical characteristics. The optical absorption band is tailorable by choice of the mixing ratio of the core/shell component to give the desired shell thickness. The core-shell structure is particularly suitable for biomedical applications such as MRI (magnetic resonance imaging) developer, specific tissue identification developer, and magnetic thermal therapy.
    Type: Grant
    Filed: September 29, 2005
    Date of Patent: April 20, 2010
    Assignee: Industrial Technology Research Institute
    Inventors: Ming-Yao Chen, Wen-Hsiang Chang, Chin-I Lin, Shian-Jy Jassy Wang, Yuh-Jiuan Lin
  • Patent number: D602387
    Type: Grant
    Filed: November 14, 2008
    Date of Patent: October 20, 2009
    Assignee: Industrial Technology Research Institute
    Inventors: Jhao-Syong Chen, Kun Feng Lee, Yu-Jin Kao, Chih Hsien Su, Yi-Shang Lin, Yuh-Jiuan Lin
  • Patent number: D634839
    Type: Grant
    Filed: August 30, 2006
    Date of Patent: March 22, 2011
    Assignee: Industrial Technology Research Institute
    Inventors: Yuh-Jiuan Lin, Hsi-Feng Kao, Kun-Feng Lee, Chung-Kai Chen
  • Patent number: D640367
    Type: Grant
    Filed: August 30, 2006
    Date of Patent: June 21, 2011
    Assignee: Industrial Technology Research Institute
    Inventors: Yuh-Jiuan Lin, Kun-Feng Lee, Hsi-Feng Kao, Hsing-Hsien Ho