Patents by Inventor Yuh-Shan Chung

Yuh-Shan Chung has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10980853
    Abstract: The present invention provides a process for the preparation of a Crassocephalum crepidioides extract, and the extract prepared thereby. The present invention further relates to a pharmaceutical composition/combination comprising the Crassocephalum crepidioides extract. The use of the extract and the composition/combination comprising the extract in the prevention or treatment of cancer is also provided.
    Type: Grant
    Filed: December 31, 2015
    Date of Patent: April 20, 2021
    Assignee: DEVELOPMENT CENTER FOR BIOTECHNOLOGY
    Inventors: Dai-Hua Tsai, Tzung Hsien Lai, Tsui Hsu Chan, Yuh Shan Chung, Li-Chuan Hsu
  • Publication number: 20190060382
    Abstract: The present invention provides a process for the preparation of a Crassocephalum crepidioides extract, and the extract prepared thereby. The present invention further relates to a pharmaceutical composition/combination comprising the Crassocephalum crepidioides extract. The use of the extract and the composition/combination comprising the extract in the prevention or treatment of cancer is also provided.
    Type: Application
    Filed: December 31, 2015
    Publication date: February 28, 2019
    Applicants: DEVELOPMENT CENTER FOR BIOTECHNOLOGY, DCB-USA LLC
    Inventors: Dai-Hua TSAI, Tzung Hsien LAI, Tsui Hsu CHAN, Yuh Shan CHUNG, Li-Chuan HSU
  • Patent number: 9872879
    Abstract: The present invention provides a process for the preparation of Plectranthus amboinicus extracts using a stirring separation method. The present invention also relates to a pharmaceutical composition comprising the Plectranthus amboinicus crude extract and/or extract for treating skin disorders, including enhancing the healing of wounds, especially in diabetic patients.
    Type: Grant
    Filed: April 29, 2013
    Date of Patent: January 23, 2018
    Assignee: DEVELOPMENT CENTER FOR BIOTECHNOLOGY
    Inventors: Rey-Yuh Wu, Yuh-Shan Chung, Yu-Yuan Wu, Ma-Li Siu, Chin-Wen Hsiao
  • Patent number: 9474777
    Abstract: An extract of Graptopetalum paraguayense prepared by a method that includes: extracting a Graptopetalum paraguayense (GP) starting material with an alcoholic solvent to produce an alcoholic extract and a residue; separating the residue from the alcoholic extract; extracting the residue with an aqueous dimethyl sulfoxide (DMSO) solvent to produce a DMSO extract; subjecting the DMSO extract to ultrafiltration using a filter having a selected molecular weight cutoff; drying a fraction retained by the filter to obtain the extract of Graptopetalum paraguayense. Uses of an extract of Graptopetalum paraguayense for the treatment or prevention of liver fibrosis, hepatic cirrhosis, liver cancer, recurrence of liver fibrosis after surgery, or recurrence of liver cancer after surgery.
    Type: Grant
    Filed: December 30, 2013
    Date of Patent: October 25, 2016
    Assignee: Development Center for Biotechnology
    Inventors: Yuh-Shan Chung, Ma-Li Siu, Tzung-Hsien Lai, Szu-Chien Yeh
  • Publication number: 20150182572
    Abstract: An extract of Graptopetalum paraguayense prepared by a method that includes: extracting a Graptopetalum paraguayense (GP) starting material with an alcoholic solvent to produce an alcoholic extract and a residue; separating the residue from the alcoholic extract; extracting the residue with an aqueous dimethyl sulfoxide (DMSO) solvent to produce a DMSO extract; subjecting the DMSO extract to ultrafiltration using a filter having a selected molecular weight cutoff; drying a fraction retained by the filter to obtain the extract of Graptopetalum paraguayense. Uses of an extract of Graptopetalum paraguayense for the treatment or prevention of liver fibrosis, hepatic cirrhosis, liver cancer, recurrence of liver fibrosis after surgery, or recurrence of liver cancer after surgery.
    Type: Application
    Filed: December 30, 2013
    Publication date: July 2, 2015
    Applicant: DEVELOPMENT CENTER FOR BIOTECHNOLOGY
    Inventors: Yuh-Shan Chung, Ma-Li Siu, Tzung-Hsien Lai, Szu-Chien Yeh
  • Publication number: 20130309337
    Abstract: The present invention provides a process for the preparation of Plectranthus amboinicus extracts using a stirring separation method. The present invention also relates to a pharmaceutical composition comprising the Plectranthus amboinicus crude extract and/or extract for treating skin disorders, including enhancing the healing of wounds, especially in diabetic patients.
    Type: Application
    Filed: April 29, 2013
    Publication date: November 21, 2013
    Applicant: DEVELOPMENT CENTER FOR BIOTECHNOLOGY
    Inventors: REY-YUH WU, YUH-SHAN CHUNG, YU-YUAN WU, MA-LI SIU, CHIN-WEN HSIAO
  • Patent number: 8449924
    Abstract: The present invention provides a process for the preparation of Plectranthus amboinicus extracts using a stirring separation method. The present invention also relates to a pharmaceutical composition comprising the Plectranthus amboinicus crude extract and/or extract for treating skin disorders, including enhancing the healing of wounds, especially in diabetic patients.
    Type: Grant
    Filed: August 29, 2007
    Date of Patent: May 28, 2013
    Assignee: Development Center for Biotechnology
    Inventors: Rey-Yuh Wu, Yuh-Shan Chung, Yu-Yuan Wu, Ma-Li Siu, Chin-Wen Hsiao
  • Patent number: 8247004
    Abstract: The present invention provides a pharmaceutical composition for treating skin disorders, including enhancing the healing of wounds for diabetic patients. Specifically, this invention relates to the use of the extracts of Plectranthus amboinicus and Centella asiatica for improving skin disorders, including enhancing the healing of wounds for diabetic patients, and a pharmaceutical composition comprising the extracts of Plectranthus amboinicus and Centella asiatica as well as a wound dressing comprising the same. The invention also provides a method for preparing the crude extract and extract of Plectranthus amboinicus.
    Type: Grant
    Filed: June 15, 2011
    Date of Patent: August 21, 2012
    Assignee: Development Center for Biotechnology
    Inventors: Rey-Yuh Wu, Yuh-Shan Chung, Yu-Yuan Wu, Ma-Li Siu, Hung-Jen Huang, Chin-Wen Hsiao
  • Publication number: 20120009281
    Abstract: The present invention provides a pharmaceutical composition for treating skin disorders, including enhancing the healing of wounds for diabetic patients. Specifically, this invention relates to the use of the extracts of Plectranthus amboinicus and Centella asiatica for improving skin disorders, including enhancing the healing of wounds for diabetic patients, and a pharmaceutical composition comprising the extracts of Plectranthus amboinicus and Centella asiatica as well as a wound dressing comprising the same. The invention also provides a method for preparing the crude extract and extract of Plectranthus amboinicus.
    Type: Application
    Filed: June 15, 2011
    Publication date: January 12, 2012
    Inventors: Rey-Yuh WU, Yuh-Shan Chung, Yu-Yuan Wu, Ma-Li Siu, Hung-Jen Huang, Chin-Wen Hsiao
  • Patent number: 7985431
    Abstract: The present invention provides a pharmaceutical composition for treating skin disorders, including enhancing the healing of wounds for diabetic patients. Specifically, this invention relates to the use of the extracts of Plectranthus amboinicus and Centella asiatica for improving skin disorders, including enhancing the healing of wounds for diabetic patients, and a pharmaceutical composition comprising the extracts of Plectranthus amboinicus and Centella asiatica as well as a wound dressing comprising the same. The invention also provides a method for preparing the crude extract and extract of Plectranthus amboinicus.
    Type: Grant
    Filed: November 28, 2006
    Date of Patent: July 26, 2011
    Assignee: Development Center for Biotechnology
    Inventors: Rey-Yuh Wu, Yuh-Shan Chung, Yu-Yuan Wu, Ma-Li Siu, Hung-Jen Huang, Chin-Wen Hsiao
  • Patent number: 7531194
    Abstract: A pharmaceutical composition comprising a crude extract or extract of Plectranthus Amboinicus (Lour.) Spreng (PA) for the treatment of rheumatoid arthritis is described. The use of the crude extract or extract of Plectranthus Amboinicus (Lour.) Spreng for the manufacture of medicaments for treating rheumatoid arthritis is also described.
    Type: Grant
    Filed: August 15, 2007
    Date of Patent: May 12, 2009
    Assignee: Development Center for Biotechnology
    Inventors: Rey-Yuh Wu, Jia-Ming Chang, Chun-Ming Cheng, Yuh-Shan Chung
  • Publication number: 20090060985
    Abstract: The present invention provides a process for the preparation of Plectranthus amboinicus extracts using a stirring separation method. The present invention also relates to a pharmaceutical composition comprising the Plectranthus amboinicus crude extract and/or extract for treating skin disorders, including enhancing the healing of wounds, especially in diabetic patients.
    Type: Application
    Filed: August 29, 2007
    Publication date: March 5, 2009
    Applicant: DEVELOPMENT CENTER FOR BIOTECHNOLOGY
    Inventors: Rey-Yuh Wu, Yuh-Shan Chung, Yu-Yuan Wu, Ma-Li Siu, Chin-Wen Hsiao
  • Publication number: 20080069911
    Abstract: The present invention provides a pharmaceutical composition comprising a crude extract or extract of Plectranthus Amboinicus (Lour.) Spreng (PA) for the treatment of rheumatoid arthritis. The present invention also provides a use of the crude extract or extract of Plectranthus Amboinicus (Lour.) Spreng for the manufacture of medicaments for treating rheumatoid arthritis.
    Type: Application
    Filed: August 15, 2007
    Publication date: March 20, 2008
    Inventors: Rey-Yuh Wu, Jia-Ming Chang, Chun-Ming Cheng, Yuh-Shan Chung
  • Publication number: 20070237841
    Abstract: The present invention provides a pharmaceutical composition for treating skin disorders, including enhancing the healing of wounds for diabetic patients. Specifically, this invention relates to the use of the extracts of Plectranthus amboinicus and Centella asiatica for improving skin disorders, including enhancing the healing of wounds for diabetic patients, and a pharmaceutical composition comprising the extracts of Plectranthus amboinicus and Centella asiatica as well as a wound dressing comprising the same. The invention also provides a method for preparing the crude extract and extract of Plectranthus amboinicus.
    Type: Application
    Filed: November 28, 2006
    Publication date: October 11, 2007
    Inventors: Rey-Yuh Wu, Yuh-Shan Chung, Yu-Yuan Wu, Ma-Li Siu, Hung-Jen Huang, Chin-Wen Hsiao
  • Publication number: 20060292246
    Abstract: A characteristic mass spectral fingerprint setting method and a rapid identification method for Chinese herbal medicines or prescriptions are provided, which comprise directly injecting extracts of Chinese herbal medicines or prescriptions into a mass spectrometer with an electrospray ionization interface via an autosampler of a liquid chromatograph without going through a separation column to make a mass spectrum analysis; performing a series of mass spectrum analyses for various Chinese herbal medicines or prescription extracts; picking out the mass spectrum peaks representing the features of each of the Chinese herbal medicines or prescriptions as respective characteristic mass spectral fingerprints to establish a characteristic mass spectral fingerprint database of the Chinese herbal medicine or prescription; directly injecting an extract of the Chinese herbal medicines or prescription to be tested into a mass spectrometer with an electrospray ionization interface to make a mass spectrum analysis; and com
    Type: Application
    Filed: June 20, 2006
    Publication date: December 28, 2006
    Inventors: Rey-Yuh Wu, Yuh-Shan Chung, Ya-Wen Kuo
  • Publication number: 20050147699
    Abstract: The present invention provides a composition for inhibiting carcinogenesis and metastasis, comprising a therapeutically effective amount of an Astragalus radix and Codonopsis pilosulae radix mixed extract. Methods of producing said Astragalus radix and Codonopsis pilosulae radix mixed extract are also provided.
    Type: Application
    Filed: December 31, 2003
    Publication date: July 7, 2005
    Inventors: Rey-Yuh Wu, Bor-Shiun Chen, Tzung-Hsien Lai, Yi-Peng Chen, Yuh-Shan Chung, Paw-Hwa Yang, Shu-Yin Su, Tsu-Hwie Liu