Patents by Inventor Yuhe Qiu

Yuhe Qiu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Humanized monoclonal antibodies against the extracellular domain of human death receptor 5
    Patent number: 9725517
    Abstract: The present invention provides a humanized monoclonal antibody against extracellular domain of human death receptor 5, comprising a light chain variable region, whose amino acid sequence has at least 90% identity with the amino acid sequence shown as SEQ ID NO: 1, a heavy chain variable region, whose amino acid sequence has at least 90% identity with the amino acid sequence shown as SEQ ID NO: 2, and constant region derived from human antibody. The present invention also provides nucleotide sequence encoding said humanized monoclonal antibody, a recombinant eukaryotic expression vector, a process for preparing the humanized monoclonal antibody, and the composition and use therefore.
    Type: Grant
    Filed: October 26, 2012
    Date of Patent: August 8, 2017
    Assignee: Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences
    Inventors: Dexian Zheng, Yuhe Qiu, Yanxin Liu
  • HUMANIZED MONOCLONAL ANTIBODIES AGAINST THE EXTRACELLULAR DOMAIN OF HUMAN DEATH RECEPTOR 5
    Publication number: 20150353638
    Abstract: The present invention provides a humanized monoclonal antibody against extracellular domain of human death receptor 5, comprising a light chain variable region, whose amino acid sequence has at least 90% identity with the amino acid sequence shown as SEQ ID NO: 1, a heavy chain variable region, whose amino acid sequence has at least 90% identity with the amino acid sequence shown as SEQ ID NO: 2, and constant region derived from human antibody. The present invention also provides nucleotide sequence encoding said humanized monoclonal antibody, a recombinant eukaryotic expression vector, a process for preparing the humanized monoclonal antibody, and the composition and use therefore.
    Type: Application
    Filed: October 26, 2012
    Publication date: December 10, 2015
    Inventors: Dexian Zheng, Yuhe Qiu, Yanxin Liu