Abstract: A stethoscope device is disclosed, which comprises a heart sound sensor comprising a sensing portion to detect a heart sound signal having a periodic first heart sound and a periodic second heart sound; an electrocardiogram sensor comprising two electrodes to detect an electrocardiogram signal having a periodic R wave; a microprocessor for extracting amplitudes of the R wave from the electrocardiogram signal and analyzing appearing positions of the R wave to provide appearing positions of a periodic notification pulse wave to a predetermined reference signal and combine the reference signal with the heart sound signal to form a sound signal; and an output unit to output the sound signal; wherein each pulse of the notification pulse wave of the sound signal provides a notification sound.