Patents by Inventor Yuhua George ZHANG

Yuhua George ZHANG has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • INTERFERON TAU FC-FUSION PROTEINS AND METHODS FOR TREATING CORONAVIRUS INFECTIONS
    Publication number: 20240018207
    Abstract: The invention provides novel Fc-fusion proteins of interferon tau and compositions thereof, methods of their preparation and therapeutic use thereof in treating coronavirus (e.g., COVID-19 virus/SARS-CoV-2 and hCoV229E) viral infections, and related diseases and conditions.
    Type: Application
    Filed: September 22, 2021
    Publication date: January 18, 2024
    Inventors: Yuhua George Zhang, Wendy Wanjin Tang
  • INTERFERON TAU AS ANTIVIRAL THERAPY
    Publication number: 20230137927
    Abstract: The invention generally relates to novel therapeutic uses of interferon tau as an antiviral agent. More particularly, the invention provides novel compositions of interferon tau and methods of therapeutic use thereof in treating viral infections and related diseases and conditions.
    Type: Application
    Filed: April 22, 2021
    Publication date: May 4, 2023
    Inventors: Yuhua George Zhang, Wendy Wanjin Tang
  • PEGYLATED INTERFERON TAU AND COMPOSITIONS AND METHODS THEREOF
    Publication number: 20230131808
    Abstract: The invention provides novel PEGylated interferon tau and therapeutic uses thereof. More particularly, the invention provides novel PEGylated interferon tau compositions, methods of their preparation, and methods of therapeutic use thereof in treating viral infections (e.g., coronavirus or flavivirus infections) and various other diseases and conditions.
    Type: Application
    Filed: April 22, 2021
    Publication date: April 27, 2023
    Inventors: Yuhua George Zhang, Wendy Wanjin Tang
  • EED INHIBITOR, AND PREPARATION METHOD THEREFOR AND USE THEREOF
    Publication number: 20230028221
    Abstract: The present invention relates to a compound of formula (X) or a tautomer, stereoisomer, prodrug, crystal form, pharmaceutically acceptable salt, hydrate or solvate thereof, and a pharmaceutical composition containing the compound and a use.
    Type: Application
    Filed: November 2, 2020
    Publication date: January 26, 2023
    Inventors: Wei Qi, Haizhen Zhang, Xin Ma, Hui Lei, Yuhua George Zhang, Yuxiu Qu
  • LIPOXIN A4 ANALOGS AND USES THEREOF
    Publication number: 20210401798
    Abstract: The invention relates to (S)-6-((1 R,2E,4E,8E,10S)-11-(4-fluorophenoxy)-1,10-dihydroxyundeca-2,4,8-trien-6-yn-1-yl)-1,4-dioxan-2-one (compound (1)), which is a lactone-containing analog of lipoxin A4 (LXA4). In particular, the invention features pharmaceutical compositions including compound (1) and the use of compound (1) for the treatment of a disorder (e.g., a fibrotic disorder or an inflammatory disorder, such as an autoimmune disorder) in a subject in need thereof.
    Type: Application
    Filed: October 23, 2019
    Publication date: December 30, 2021
    Applicants: The Brigham and Women's Hospital, Inc., Corbus Pharmaceuticals, Inc., Corbus Pharmaceuticals, Inc.
    Inventors: Nan CHIANG, Sheldon N. CRANE, Thomas JENNEQUIN, Valdas JURKAUSKAS, Clifton D. LEIGH, Kristos Adrian MOSHOS, Charles N. Serhan, Mark A. Tepper, Yuhua George Zhang
  • CANNABINOIDS AND USES THEREOF
    Publication number: 20210284621
    Abstract: The invention relates to cannabinoid compounds, pharmaceutical compositions including one or more cannabinoid compounds, and the use of pharmaceutical compositions including one or more cannabinoid compounds for the treatment of a disease or condition (e.g., a fibrotic disease or an inflammatory disease) in a subject in need thereof.
    Type: Application
    Filed: May 31, 2019
    Publication date: September 16, 2021
    Inventors: Kristos Adrian MOSHOS, Clifton D. LEIGH, Yuhua George ZHANG, Mark TEPPER, Hongfeng DENG