Abstract: Provided is a tetravalent homodimeric bispecific antibody molecule simultaneously targeting an immune effector cell antigen CD3 and a tumor-associated antigen, wherein the bispecific antibody molecule contains, in order from N-terminus to C-terminus, a first single chain Fv, a second single chain Fv and a Fc fragment; wherein the first single chain Fv can specifically bind to the tumor-associated antigen, the second single chain Fv can specifically bind to CD3, and the first and the second single chain Fvs are connected by a linker peptide, while the second single chain Fv and the Fc fragment are directly connected or connected by a linker peptide; and the Fc fragment does not have effector functions such as CDC, ADCC and ADCP.

Abstract: The present invention addresses the problem of limiting power consumption and radio wave interference when assessing the movements of multiple sites of a living body. The present invention is a movement function assessment system provided with: a movement function measurement apparatus for calculating movement data on the basis of the relative distances of pairs of transmission coils and reception coils attached to movable portions of a living body; and an assessment apparatus for assessing the movement function of the living body on the basis of the movement data received from the movement function measurement apparatus. A control unit of the movement function measurement apparatus performs the switching of the multiple transmission coils by a switching unit (1) and the switching of the multiple reception coils by a switching unit (2) so that the paired transmission coils and reception coils are operated sequentially.

Abstract: An object of the present invention is to provide a durometer enabling a contact portion in contact with an object to perform smooth piston motion. The durometer includes a main body unit including a movable unit pressed continuously against an object to be measured, a first sensor outputting acceleration information corresponding to an acceleration of movement of a contact part of the object to be measured in contact with the movable unit in a pressing direction, a second sensor outputting reactive force information corresponding to a reactive force at the contact part of the object to be measured in contact with the movable unit, a motor, a crank mechanism driven by the motor and causing the main body unit and the movable unit to perform piston motion, and at least one buffering member disposed on a periphery of the main body unit.

Abstract: An object of the present invention is to provide a durometer enabling a contact portion in contact with an object to perform smooth piston motion. The durometer includes a main body unit including a movable unit pressed continuously against an object to be measured, a first sensor outputting acceleration information corresponding to an acceleration of movement of a contact part of the object to be measured in contact with the movable unit in a pressing direction, a second sensor outputting reactive force information corresponding to a reactive force at the contact part of the object to be measured in contact with the movable unit, a motor, a crank mechanism driven by the motor and causing the main body unit and the movable unit to perform piston motion, and at least one buffering member disposed on a periphery of the main body unit.

Abstract: Provided is a gyroscope including: a first inertial body that is displaceable in a first direction and a second direction perpendicular to the first direction; a second inertial body that is displaceable in the first direction and the second direction; a third inertial body that is displaceable in the first direction and the second direction; a fourth inertial body that is displaceable in the first direction and the second direction; a first connection unit that supports the first inertial body; a second connection unit that supports the second inertial body; a third connection unit that supports the third inertial body; a fourth connection unit that supports the fourth inertial body; and a connection body that is provided among the first inertial body, the second inertial body, the third inertial body, and the fourth inertial body and connects the first inertial body, the second inertial body, the third inertial body, and the fourth inertial body.

Abstract: An object of the present invention is to provide a durometer enabling a contact portion in contact with an object to perform smooth piston motion. The durometer includes a main body unit including a movable unit pressed continuously against an object to be measured, a first sensor outputting acceleration information corresponding to an acceleration of movement of a contact part of the object to be measured in contact with the movable unit in a pressing direction, a second sensor outputting reactive force information corresponding to a reactive force at the contact part of the object to be measured in contact with the movable unit, a motor, a crank mechanism driven by the motor and causing the main body unit and the movable unit to perform piston motion, and at least one buffering member disposed on a periphery of the main body unit.

Abstract: An object of the present invention is to provide a durometer enabling a contact portion in contact with an object to perform smooth piston motion. The durometer includes a main body unit including a movable unit pressed continuously against an object to be measured, a first sensor outputting acceleration information corresponding to an acceleration of movement of a contact part of the object to be measured in contact with the movable unit in a pressing direction, a second sensor outputting reactive force information corresponding to a reactive force at the contact part of the object to be measured in contact with the movable unit, a motor, a crank mechanism driven by the motor and causing the main body unit and the movable unit to perform piston motion, and at least one buffering member disposed on a periphery of the main body unit.

Abstract: A battery life extender for a portable lighting device employs a reconfigurable mechanism operable to selectively electrically isolate one or more batteries from a circuit having a parasitic power drain. For example, a lighting device includes a light generating element, at least one battery, a user operated switch configured to control delivery of electrical power from the at least one battery to the light generating element, and a housing assembly supporting the at least one battery and the light generating element. The user operated switch can impart a parasitic power drain. The housing assembly is reconfigurable to: (a) a first configuration in which the user operated switch is electrically connected to the at least one battery, and (b) a second configuration in which the at least one battery is electrically isolated and the at least one battery is retained by the housing assembly.

Abstract: Provided is a gyroscope including: a first inertial body that is displaceable in a first direction and a second direction perpendicular to the first direction; a second inertial body that is displaceable in the first direction and the second direction; a third inertial body that is displaceable in the first direction and the second direction; a fourth inertial body that is displaceable in the first direction and the second direction; a first connection unit that supports the first inertial body; a second connection unit that supports the second inertial body; a third connection unit that supports the third inertial body; a fourth connection unit that supports the fourth inertial body; and a connection body that is provided among the first inertial body, the second inertial body, the third inertial body, and the fourth inertial body and connects the first inertial body, the second inertial body, the third inertial body, and the fourth inertial body.

Abstract: A gyroscope includes connecting portions which are provided between a mass body and a mass body and connects the mass body with the mass body. Here, the connecting portions includes a fixing portion fixed to a substrate, a shuttle provided between the fixing portion and the mass body, a shuttle provided between the fixing portion and the mass body, a beam connecting the fixing portion with the shuttle, a beam connecting the fixing portion with the shuttle, a beam connecting the mass body with the shuttle, a beam connecting the mass body with the shuttle, and a beam connecting the shuttle with the shuttle. The fixing portion is provided between the shuttle and the shuttle.

Abstract: An object of the present invention is to provide a technique of quantitatively measuring physical properties including both of viscosity and elasticity. A viscoelasticity measurement system includes a measurement apparatus, a processor, and a display apparatus. The measurement apparatus includes a movable unit continuously pressed against a measurement object, a first sensor outputting acceleration information corresponding to an acceleration of pressing-directional movement of a contact portion of the movable unit with respect to the measurement object, and a second sensor outputting reactive force information corresponding to a reactive force applied to the contact portion of the movable unit with respect to the measurement object. The processor calculates first information on an elasticity component of the measurement object and second information on a viscosity component of the measurement object based on the acceleration information and the reactive force information.

Abstract: An object of the present invention is to provide a durometer enabling a contact portion in contact with an object to perform smooth piston motion. The durometer includes a main body unit including a movable unit pressed continuously against an object to be measured, a first sensor outputting acceleration information corresponding to an acceleration of movement of a contact part of the object to be measured in contact with the movable unit in a pressing direction, a second sensor outputting reactive force information corresponding to a reactive force at the contact part of the object to be measured in contact with the movable unit, a motor, a crank mechanism driven by the motor and causing the main body unit and the movable unit to perform piston motion, and at least one buffering member disposed on a periphery of the main body unit.

Abstract: Provided is a device design support apparatus in which a data input-output portion receives an input of a first device provisional specification relating to a device from a customer, a database generating portion generates a second database based on a first database stored in a database storing portion and the first device provisional specification, and a device specification generating portion generates a second device provisional specification relating to the device based on the second database, presents the second device provisional specification to the customer by outputting the generated second device provisional specification through the data input-output portion, receives the input of a change content of the second device provisional specification from the customer, and generates a device fixed specification of the device based on the second device provisional specification and the change content.

Abstract: A movable part rotates about a rotation axis, which passes through a support, when an inertial force in a detecting direction is applied to an inertial sensor. The movable part includes a first region and a second region displaced in a direction opposite to a direction of the first region when the inertial force is applied. A second substrate includes first and second detection electrodes opposed to the first and second regions, respectively. The first detection electrode and the second detection electrode are provided symmetrically with respect to the rotation axis. A cavity is provided symmetrically with respect to the rotation axis. In a direction perpendicular to the detecting direction and a direction in which the rotation axis extends, a length from the rotation axis to an end of the first region and a length from the rotation axis to an end of the second region are different.

Abstract: The present invention provides a technique for determining the circuit configuration and device structure that meet required specifications in a short time. A device design support method includes: a step (S2) of receiving an input of specifications of a sensor, and extracting the circuit configuration and device specification range corresponding to the received specifications of the sensor, by referring to a circuit design database in which the circuit configuration configuring the sensor, the range of the specifications of the device configuring the sensor, and the specifications of the sensor are associated with each other; and a step (S3) of extracting the device structure corresponding to the extracted device specification range by referring to a device design database in which the specifications of the device and the structure of the device are associated with each other.

Abstract: A battery life extender (12) for a portable lighting device (10) employs a reconfigurable mechanism operable to selectively electrically isolate one or more batteries (20) from a circuit having a parasitic power drain. For example, a lighting device (10) includes a light generating element (14), at least one battery (20), a user operated switch (16) configured to control delivery of electrical power from the at least one battery (20) to the light generating element (14), and a housing assembly (18) supporting the at least one battery (20) and the light generating element (14). The user operated switch (16) can impart a parasitic power drain. The housing assembly (18) is reconfigurable to: (a) a first configuration in which the user operated switch (16) is electrically connected to the at least one battery (20), and (b) a second configuration in which the at least one battery (20) is electrically isolated and the at least one battery (20) is retained by the housing assembly (18).

Abstract: The present invention addresses the problem of limiting power consumption and radio wave interference when assessing the movements of multiple sites of a living body. The present invention is a movement function assessment system provided with: a movement function measurement apparatus for calculating movement data on the basis of the relative distances of pairs of transmission coils and reception coils attached to movable portions of a living body; and an assessment apparatus for assessing the movement function of the living body on the basis of the movement data received from the movement function measurement apparatus. A control unit of the movement function measurement apparatus performs the switching of the multiple transmission coils by a switching unit (1) and the switching of the multiple reception coils by a switching unit (2) so that the paired transmission coils and reception coils are operated sequentially.

Abstract: A battery life extender (12) for a portable lighting device (10) employs a reconfigurable mechanism operable to selectively electrically isolate one or more batteries (20) from a circuit having a parasitic power drain. For example, a lighting device (10) includes a light generating element (14), at least one battery (20), a user operated switch (16) configured to control delivery of electrical power from the at least one battery (20) to the light generating element (14), and a housing assembly (18) supporting the at least one battery (20) and the light generating element (14). The user operated switch (16) can impart a parasitic power drain. The housing assembly (18) is reconfigurable to: (a) a first configuration in which the user operated switch (16) is electrically connected to the at least one battery (20), and (b) a second configuration in which the at least one battery (20) is electrically isolated and the at least one battery (20) is retained by the housing assembly (18).

Abstract: A battery life extender for a portable lighting device employs a reconfigurable mechanism operable to selectively electrically isolate one or more batteries from a circuit having a parasitic power drain. For example, a lighting device includes a light generating element, at least one battery, a user operated switch configured to control delivery of electrical power from the at least one battery to the light generating element, and a housing assembly supporting the at least one battery and the light generating element. The user operated switch can impart a parasitic power drain. The housing assembly is reconfigurable to: (a) a first configuration in which the user operated switch is electrically connected to the at least one battery, and (b) a second configuration in which the at least one battery is electrically isolated and the at least one battery is retained by the housing assembly.

Abstract: A method for vertically grounding and leading down form an outer side of a composite pole tower and pole tower thereof, wherein the method includes the following steps: extending an upper metal cross arm from an extended line of at least one side of a ground wire cross arm, vertically leading down a ground down-leading wire from a distal end of the upper metal cross arm, connecting the ground down-leading wire to the pole tower via a lower metal cross arm at a distance under a lower lead, and grounding the ground down-leading wire along a tower body of the pole tower, wherein when an lower portion of the tower body is a metal pipe, the ground down-leading wire is selectively directly connected to the metal pipe via the lower metal cross arm.