Abstract: A sampling capsule is provided. The sampling capsule includes an enclosure, a sampling assembly, a sample drawing assembly and a control module. The sampling assembly includes a sample chamber arranged in the enclosure, an outer sampling port on the enclosure, a sampling tube connecting the outer sampling port and the sample chamber, and a sampling switch for opening or closing the connecting tube. The sample drawing assembly includes a sample drawing port on the enclosure and connected to the sample chamber, and a silicone plug fitted in the sample discharging port. The control module includes a microprocessor communicating with the sampling switch.

Abstract: The present invention provides a capsule for fluid sampling and drug delivery comprising: an enclosure, comprising a first enclosure, a second enclosure, at least a portion of the first enclosure comprising a support body having a plurality of first openings, a liquid-proof air-permeable membrane located at the first openings; a sampling/drug delivery assembly, comprising a storage chamber at least partially enclosed by the liquid-proof air-permeable membrane, a temporary storage chamber located in the enclosure, a first one-way element connecting the temporary storage chamber to outside of the capsule, a second one-way element connecting the temporary storage chamber to the storage chamber, and a pump changing pressure in the temporary storage chamber, wherein the first one-way element and the second one-way element have same direction of access; and a control module, comprising a microprocessor in communication with the pump. The capsule can realize multiple times of sampling and drug delivery.

Abstract: The present invention provides a capsule for fluid sampling and drug delivery including: an enclosure; a sampling/drug delivery assembly, including a storage chamber arranged in the enclosure, a first one-way element and a second one-way element communicating with outside of the capsule and the storage chamber, and a pump changing pressure in the storage chamber, wherein the first one-way element and the second one-way element have same direction of access; and a control module, including a microprocessor in communication with the pump. The capsule can realize multiple times of sampling and drug delivery by means of control flow direction of sample or drug through the first one-way element and the second one-way element, and by changing the pressure of the storage chamber through the pump.

Abstract: The present invention provides a gastrointestinal sampling capsule includes an enclosure, a sampling port on the enclosure and a sampling module connected to the enclosure. The sampling port includes a plurality of sampling holes, and the sampling module includes a sample chamber and a sampling trigger unit which controls a connection or disconnection between the sampling port and the sample chamber to turn on sampling or turn off sampling. The gastrointestinal sampling capsule further includes a connecting passage arranged between the sample chamber and the sampling port, wherein an inlet of the connecting passage corresponds to the sampling port and an outlet of the connecting passage is connected to the sample chamber. A gap is provided between the plurality of sampling holes and the inlet of the connecting passage, through which the plurality of sampling holes are connected to the connecting passage.

Abstract: A sampling capsule is provided. The sampling capsule includes an enclosure, a sampling assembly, a sample drawing assembly and a control module. The sampling assembly includes a sample chamber arranged in the enclosure, an outer sampling port on the enclosure, a sampling tube connecting the outer sampling port and the sample chamber, and a sampling switch for opening or closing the connecting tube. The sample drawing assembly includes a sample drawing port on the enclosure and connected to the sample chamber, and a silicone plug fitted in the sample discharging port. The control module includes a microprocessor communicating with the sampling switch.

Abstract: A sampling capsule and sampling capsule system are provided. The sampling capsule includes an enclosure, a sampling assembly, a mucosal flora collection auxiliary assembly and a control module. The sampling assembly includes a sample chamber disposed in the enclosure, an outer sampling port on the enclosure, a connecting tube connecting the outer sampling port and the sample chamber, and a sampling switch for opening or closing the connecting tube. The mucosal flora collection auxiliary assembly includes a vibration motor disposed in the enclosure, and/or a counterweight at the outer sampling port. The control module includes a microprocessor in communication with the sampling switch and the vibration motor.

Abstract: The present invention provides a gastrointestinal sampling capsule includes an enclosure, a sampling port on the enclosure and a sampling module connected to the enclosure. The sampling port includes a plurality of sampling holes, and the sampling module includes a sample chamber and a sampling trigger unit which controls a connection or disconnection between the sampling port and the sample chamber to turn on sampling or turn off sampling. The gastrointestinal sampling capsule further includes a connecting passage arranged between the sample chamber and the sampling port, wherein an inlet of the connecting passage corresponds to the sampling port and an outlet of the connecting passage is connected to the sample chamber. A gap is provided between the plurality of sampling holes and the inlet of the connecting passage, through which the plurality of sampling holes are connected to the connecting passage.

Abstract: Disclosed is a method for the synthesis of 6-iodo-2-oxindole useful as intermediate in the manufacture of pharmaceutically active ingredients. Also disclosed is a novel intermediate used in the synthesis of this compound.

Abstract: Disclosed is a method for the synthesis of 6-iodo-2-oxindole useful as intermediate in the manufacture of pharmaceutically active ingredients. Also disclosed is a novel intermediate used in the synthesis of this compound.