Abstract: This gear wheel mechanism includes a rotator, a first gear wheel, a second gear wheel, and a reinforcement member. The rotator is configured to be rotatable about a rotation shaft and has an elliptical shape as viewed in an axis direction of the rotation shaft. The first gear wheel includes a first base portion including a first outer circumferential surface and a first inner circumferential surface and having a hollow cylindrical shape configured to be deformable by the rotator being inserted in the axis direction of the rotation shaft and external teeth formed in the outer circumferential surface.

Abstract: This gear wheel mechanism includes a rotator, a first gear wheel, a second gear wheel, and a reinforcement member. The rotator is configured to be rotatable about a rotation shaft and has an elliptical shape as viewed in an axis direction of the rotation shaft. The first gear wheel includes a first base portion including a first outer circumferential surface and a first inner circumferential surface and having a hollow cylindrical shape configured to be deformable by the rotator being inserted in the axis direction of the rotation shaft and external teeth formed in the outer circumferential surface.

Abstract: To provide a high-quality and high-performance micro-channel device which can be manufactured by a simple method. Provided is a micro-channel device used in analyzing a sample. The micro-channel device includes at least two substrates and an elastic film interposed between the two substrates. The substrates are thermally fused to the elastic film in at least a part thereof. Also provided is a method for manufacturing a micro-channel device used in analyzing a sample. The method includes a surface activation step of activating a joining surface of a substrate and/or an elastic film, a lamination step of laminating the elastic film between at least two of the substrates, and a thermal fusion step of thermally fusing the substrates to the elastic film in at least a part thereof.

Abstract: A method of manufacturing a flexible gear and a method of manufacturing a flexible gear unit that can achieve a further improvement in productivity and a further reduction in production cost, and a gear that allows a further improvement in productivity and a further reduction in production cost are provided. A method of manufacturing a flexible gear is provided which includes preparing a matrix with a flexible gear shape, and forming, by an electroforming method using the matrix, a flexible gear shape with predetermined thickness and releasing the flexible gear shape from the matrix. A method of manufacturing a flexible gear unit is provided which includes the method of manufacturing the flexible gear according to the present technology, and joining a shaft and/or a hub to the flexible gear. Further, a gear is provided which includes a gear part, a body part, and a diaphragm part, is made from a material suitable for an electroforming method, and has flexibility.

Abstract: The present invention relates to a novel method for producing diarylpyridine derivatives, and the object of the present invention is to provide a novel, industrially useful method. The present inventors developed a novel method for synthesizing pyridine rings without using palladium, a strong base, or a high-temperature reaction. In particular, they successfully developed a method that can be used to synthesize iminium salts as intermediates, synthesize cyano compounds from these iminium salts, and cyclize the cyano compounds into pyridines under very mild reaction conditions.

Abstract: It is an object of the present invention to provide an excellent method for producing an excellent therapeutic agent. The solution of the present invention is as shown in the following scheme: wherein R1 represents a C1-C6 alkyl group, R2 represents a C1-C6 alkyl group, and R3 represents a C1-C6 alkyl group.

Abstract: To provide a high-quality and high-performance micro-channel device which can be manufactured by a simple method. Provided is a micro-channel device used in analyzing a sample. The micro-channel device includes at least two substrates and an elastic film interposed between the two substrates. The substrates are thermally fused to the elastic film in at least a part thereof. Also provided is a method for manufacturing a micro-channel device used in analyzing a sample. The method includes a surface activation step of activating a joining surface of a substrate and/or an elastic film, a lamination step of laminating the elastic film between at least two of the substrates, and a thermal fusion step of thermally fusing the substrates to the elastic film in at least a part thereof.

Abstract: It is an object of the present invention to provide a medicament for preventing or treating hyperphosphatemia. The solution is crystals, or hydrate thereof, of a salt of a compound represented by formula (I).

Abstract: It is an object of the present invention to provide an excellent method for producing an excellent therapeutic agent. The solution of the present invention is as shown in the following scheme: wherein R1 represents a C1-C6 alkyl group, R2 represents a C1-C6 alkyl group, and R3 represents a C1-C6 alkyl group.

Abstract: It is an object of the present invention to provide a medicament for preventing or treating hyperphosphatemia. The solution is crystals, or hydrate thereof, of a salt of a compound represented by formula (I).

Abstract: A conductive substrate includes substrate made of a resin material, and a conductive layer formed on the substrate by baking a conductive paste which is coated on the substrate at a predetermined position, wherein the conductive layer is formed through baking by applying second laser light to the conductive paste of which a position on the substrate is detected based on a difference in reflectance depending on the application positions of first laser light applied to the substrate.

Abstract: An image sensor is provided. The image sensor includes a photoelectric conversion portion including a light receiving element; and a well region defined by a wall structure that is formed integrally on the photoelectric conversion portion, wherein the well region is positioned to correspond to the light receiving element of the photoelectric conversion portion. An image sensor device and methods of manufacture are also provided.

Abstract: There is provided an optical modeling apparatus that forms a model of a desired shape by sequentially forming hardened layers by irradiating a light-curable resin with light. The apparatus includes a first light source that emits a light beam for plotting on the resin, a scanning device that scans the light beam from the first light source over the resin, a second light source that emits light that irradiates one fixed region of the resin at a time, and a spatial light modulator that spatially modulates the light from the second light source to blanket-expose a specified region of the resin. The light beam from the scanning device and the light from the spatial light modulator form each hardened layer.

Abstract: There is provided an optical modeling apparatus that forms a model of a desired shape by sequentially forming hardened layers by irradiating a light-curable resin with light. The apparatus includes a first light source that emits a light beam for plotting on the resin, a scanning device that scans the light beam from the first light source over the resin, a second light source that emits light that irradiates one fixed region of the resin at a time, and a spatial light modulator that spatially modulates the light from the second light source to blanket-expose a specified region of the resin. The light beam from the scanning device and the light from the spatial light modulator form each hardened layer.

Abstract: A bioassay plate is provided with a pair of opposing electrodes in a reaction region, and by imposing a predetermined electric field on the reaction region, the bioassay plate makes it possible to perform high-order structural adjustment, migration, immobilization and the like of a substance as desired. A first substrate (11) is provided with a detection well (X), which is in turn equipped at least with a reaction region (R) for providing a place of interaction between the substances and also with a first electrode (E11) arranged facing the reaction region (R). A second substrate (12) is provided at least with a second electrode (E12) which can impose an electric field on the reaction region (R) in association with the first electrode (E11). The present invention provides a bioassay plate (1) formed of these two substrates (11), (12) stacked together such that the first electrode (E11) and the second electrode (E12) are located opposite to each other, and also a production method of the plate (1).

Abstract: A detection apparatus, a detection method and an electron beam irradiation apparatus for detecting deflection electrons in order to precisely focus even if a vacuum seal valve is provided. An electron beam irradiation apparatus including a vacuum seal valve mechanism which is provided in a static pressure floating pad, and opens/closes an electron beam passage with a piston so as to switch between an electron beam irradiation state and a vacuum seal state, and a deflection electron detector which is provided between the vacuum seal valve mechanism and a master disk and detects a deflection electron signal generated from the master disk with electron beam irradiation.

Abstract: An electron beam irradiation apparatus, includes a support section for supporting an electron beam irradiation subject to be irradiated with an electron beam, and an electron beam irradiation head opposed to the electron beam irradiation subject via a minute space, the electron beam irradiation head having an electron beam emission hole for irradiating the electron beam irradiation subject with the electron beam. In the electron beam irradiation head, an electron beam path communicating with the electron beam emission hole is provided, and in addition one or more ring shaped gas suction grooves opened from a surface of the electron beam irradiation head facing the electron beam irradiation subject is formed around the electron beam emission hole. Vacuum pumps are coupled to the electron beam path and the ring shaped gas suction grooves, and the electron beam path is held in a high vacuum state.

Abstract: A testing apparatus using a scanning electron microscope for enabling tests and measurements on any part of a test subject in a nondestructive way without being limited by a size of the test subject, which is, a testing apparatus 1 using a scanning electron microscope for performing tests and measurements on any part of a test subject in a nondestructive way by using a scanning electron microscope 6a, comprising a local vacuum formation portion 9 for forming a local vacuum region by blocking around a part to be tested of the test subject from the outside air, wherein the local vacuum formation portion comprises an exhaust portion for exhausting to form a partial vacuum region, a float means 14 for floating the whole local vacuum formation portion above the test subject by emitting a compressed gas to an outer circumference portion of the local vacuum formation portion and a length measuring means 16 for measuring a distance between the test subject and the local vacuum formation portion for controlling floati

Abstract: This invention relates to a manufacturing method for an optical information recording medium and a manufacturing device for an optical information recording medium, and is applicable for instance to devices for optical disks, capable of focusing a laser beam from an exposure semiconductor laser at high density onto a base disk. This invention compensates the chromatic aberrations of the objective lens with a chromatic aberration optical system or compensates for fluctuations in the wavelength by regulating the temperature of the semiconductor laser.

Abstract: An electron beam irradiation apparatus in a partial vacuum method is structured with a static pressure floating pad 18 connected to a vacuum chamber 14 containing an electron beam column 15 and in a condition that the static pressure floating pad 18 is attached to a subject 1 to be irradiated without contacting, and an electron beam irradiating the subject 1 to be irradiated through an electron beam path 19 of the static pressure floating pad 18, whereby the vacuum chamber and the electron beam column can be maintained in the required degree of vacuum even in a condition that the static pressure floating pad 18 is separated from the subject 1 to be irradiated. A vacuum seal valve 30 including a piston to open and close the electron beam path 19 is provided within the static pressure floating pad 18.