Abstract: A method for improving the delayed fracture characteristics of a metal sheet made of a high-strength steel sheet to suppress delayed fracture from a sheared end face after forming by a simple method. A method for improving delayed fracture characteristics of a metal sheet, the metal sheet having a sheared end face on at least a part of a sheet end portion and being made of a high-strength steel sheet. Plastic deformation is imparted to at least a part of the sheared end face of the metal sheet.

Abstract: A configuration is provided in which two high-frequency power transmission antennas 111, 121 formed on two microstrip lines 101, 102, respectively, are disposed to face each other with an insulating sheet 103 interposed between the two high-frequency power, and the high-frequency power transmission antennas 111, 121 are formed on the two microstrip lines 101, 102, respectively, to realize transmission of high-frequency power, to make it possible to reduce the size of a DC block as compared with a conventional DC block using a coaxial line shape or a waveguide shape, and make it possible to highly efficiently transmit only high-frequency power while cutting off high-voltage direct-current power by the insulating sheet 103.

Abstract: The present invention provides a compound having a Pim-1 inhibitory activity. The present invention provides a compound of Formula [I] or a pharmaceutically acceptable salt thereof, a pharmaceutical composition containing the same, and a pharmaceutical use thereof, and the like. wherein each symbol is as defined in the description.

Abstract: The present invention provides a compound having a Pim-1 inhibitory activity. The present invention provides a compound of Formula [I] or a pharmaceutically acceptable salt thereof, a pharmaceutical composition containing the same, and a pharmaceutical use thereof, and the like. wherein each symbol is as defined in the description.

Abstract: Provided is a compound having an mPGES-1 inhibitory activity and useful for the prophylaxis or treatment of pain, rheumatism, osteoarthritis, fever, Alzheimer's disease, multiple sclerosis, arteriosclerosis, glaucoma, ocular hypertension, ischemic retinal disease, systemic scleroderma and cancer including colorectal cancer. A compound represented by the formula [I] or a pharmaceutically acceptable salt thereof: wherein each symbol is as defined in the SPECIFICATION.

Abstract: The present invention provides a compound having a Pim-1 inhibitory activity. The present invention provides a compound of Formula [I] or a pharmaceutically acceptable salt thereof, a pharmaceutical composition containing the same, and a pharmaceutical use thereof, and the like. wherein each symbol is as defined in the description.

Abstract: The invention provides a compound having a GLUT9 inhibitory activity. The compound is of Formula [I] wherein each symbol is as defined in the specification, or a pharmaceutically acceptable salt thereof.

Abstract: Provided is a compound having an mPGES-1 inhibitory activity and useful for the prophylaxis or treatment of pain, rheumatism, osteoarthritis, fever, Alzheimer's disease, multiple sclerosis, arteriosclerosis, glaucoma, ocular hypertension, ischemic retinal disease, systemic scleroderma and cancer including colorectal cancer. A compound represented by the formula [I] or a pharmaceutically acceptable salt thereof: wherein each symbol is as defined in the SPECIFICATION.

Abstract: The invention provides a compound having a GLUT9 inhibitory activity. The compound is of Formula [I] wherein each symbol is as defined in the specification, or a pharmaceutically acceptable salt thereof.

Abstract: Provided is a compound having an mPGES-1 inhibitory activity and useful for the prophylaxis or treatment of pain, rheumatism, osteoarthritis, fever, Alzheimer's disease, multiple sclerosis, arteriosclerosis, glaucoma, ocular hypertension, ischemic retinal disease, systemic scleroderma and cancer including colorectal cancer. A compound represented by the formula [I] or a pharmaceutically acceptable salt thereof: wherein each symbol is as defined in the SPECIFICATION.

Abstract: A rolling bearing adapted to prevent crack formation in a caulking portion is provided. A rolling bearing assembly includes: a hub shaft having the caulking portion at an axial end thereof, the caulking portion bendably deformed in a radially outward direction; the rolling bearing mounted on an outside surface of the hub shaft; and an annular member spline-engaged with the hub shaft and caulk-fixed to place by the caulking portion. An inner-side axial end of a second male spline formed on the hub shaft is shifted from an inner-side end of the hub shaft toward an outer side far enough to ensure that the second male spline is not susceptible to the plastic deformation of the caulked caulking portion.

Abstract: A 5-membered heteroaromatic ring compound represented by the formula [I] wherein V is CH or N; W is S or O; R1 and R2 are each H etc.; X is —N(R4)—, —O—, —S—, —SO2—N(R5)—, —CO—N(R7)— etc.; L is wherein R20, R21, R22 and R25 are each H etc.; E is aryl or heteroaromatic ring group; R is —COOH etc.; B is aryl etc.; R3 is H etc.; Y is —C(R13)(R14)—N(R12)—C(R13)(R14)—O—, —N(R11)—, —O— etc.; A is alkylene; and Z is aryl etc., a prodrug thereof and a pharmaceutically acceptable salt thereof. The compound [I] has a superior protein tyrosine phosphatase 1B inhibitory activity and is useful as a therapeutic agent for diabetes, diabetic complications, hyperlipidemia, obesity and the like.

Abstract: This invention relates to a self-locking agent consisting essentially of a mixture of a polyamide or a copolyamide and an epoxy resin and a phenol resin, isocyanate compound, titanate, silane coupling agent or an organo-silicon compound and methods of making and using said agent.