Abstract: Very simple, highly sensitive detection or quantification of target nucleic acids of interest has been achieved by: hybridizing mask oligonucleotides to regions in a single-stranded region of a nucleic acid to be assayed between which a region to be hybridized by an oligonucleotide probe is positioned, thereby opening the probe-hybridizing region and keeping the single-stranded region of the target nucleic acid stable, and then subjecting this nucleic acid having the single-stranded region to nucleic acid chromatography.

Abstract: Very simple, highly sensitive detection or quantification of target nucleic acids of interest has been achieved by: hybridizing mask oligonucleotides to regions in a single-stranded region of a nucleic acid to be assayed between which a region to be hybridized by an oligonucleotide probe is positioned, thereby opening the probe-hybridizing region and keeping the single-stranded region of the target nucleic acid stable, and then subjecting this nucleic acid having the single-stranded region to nucleic acid chromatography.

Abstract: A microchip, which is used in a diagnostic system using a microfluid system, has a flow path capable of greatly improving the reaction efficiency and realizing a stable measurement with high reproducibility. The microchip has two substrates with at least a flow path 12 formed at the interface between the two substrates, the flow path 12 having a reaction area 14 and a detection area 15 downstream of the reaction area 14, and the flow path 12 at the detection area 15 having a depth which is deeper than the flow path 12 in the reaction area 14.

Abstract: The invention provides an analytical device insusceptible to inactivation or other influences even when exposed to a thermal load or organic compounds contained in an adhesive in the process for manufacturing the same and, more over, allowing an immunological substance or the like to be readily immobilized at a site in the microchannel passage therein. The analytical kit is a combination of the analytical device and a reagent or reagents. The analytical device used in the analytical kit comprises a passage 2, 1 ?m-5mm width and 1 ?m-750 ?m depth in cross-section formed therein and belongs to the category of the so-called microfluidic systems suited for analyzing very small amounts of liquid samples; thus, it is suited for analyzing biological substances.

Abstract: Polynucleotides which are produced by preadipocytes within 12 hours from the start of adipocyte differentiation induction and comprise a base sequence identical or at least 93% homologous to SEQ ID NO:1, or a base sequence identical to SEQ ID NO:9, or polynucleotides complementary to those polynucleotides, and proteins comprising an amino acid sequence identical or at least 96% homologous to the protein shown under SEQ ID NO:2 or comprising the amino acid sequence shown under SEQ ID NO:10 are provided.

Abstract: Polynucleotides which are produced by preadipocytes within 12 hours from the start of adipocyte differentiation induction and comprise a base sequence identical or at least 93% homologous to SEQ ID NO:1, or a base sequence identical to SEQ ID NO:9, or polynucleotides complementary to those polynucleotides, and proteins comprising an amino acid sequence identical or at least 96% homologous to the protein shown under SEQ ID NO:2 or comprising the amino acid sequence shown under SEQ ID NO:10 are provided.

Abstract: A housing for an immunochromatography apparatus capable of detecting the concentration of an analyte contained in a sample even if it is relatively low in concentration is provided. In the housing 1 of immunochromatography apparatus having an observation window 5, the observation window 5 of the housing 1 is made of a colored transparent plastic material having a transmittance of at least 20%, preferably at least 40%, so that a detection line displayed on a developing strip 2 contained therewithin can be seen therethrough, the other portion of the housing than the observation window 5 is made of a colored transparent plastic material having a transmittance of at least 12%, and the observation window 5 and the housing 1 are simultaneously and integrally molded out of the same plastic material.

Abstract: Providing an assay method capable of simultaneously determining the presence or absence of one or more species of biological substances or assaying the amounts thereof with a single assay device, a kit therefor and an assay device thereof.

Abstract: Providing an assay method capable of simultaneously determining the presence or absence of one or more species of biological substances or assaying the amounts thereof with a single assay device, a kit therefor and an assay device thereof.

Abstract: The assay reagent and kit of the present invention suppress non-specific binding of a labeled substance onto a solid phase, and can assay one or more species of antibodies or one or more species of antigens by means of a single reagent in a simple manner. The assay method involves reacting immunological ligands in a test sample with the assay reagent which contains a combination of components (A) and (B), thereby forming complexes, which complexes are captured onto the independently and separately present Solid phases (C), to assay the label contained in the complexes.