Abstract: A medical device is capable of aspirating an object in a body lumen, while preventing the retention of the object therein, and effectively discharging the object. The medical device includes: a rotatable drive shaft having a lumen; a cutting portion fixed to a distal portion of the drive shaft to cut the object; and a housing that contains a proximal portion of the drive shaft and has a discharge port through which the cut object is discharged. The drive shaft has a proximal opening portion that extends around a portion of a circumference of the drive shaft to expose a discharge opening. The discharge port includes a discharge hole through which the cut object discharged through the discharge opening of the proximal opening portion is discharged from the housing, and a guide surface that protrudes toward the proximal opening portion to guide the cut object into the discharge hole.

Abstract: Provided is a medical device capable of easily changing a position of the device inside a biological lumen and effectively removing a cut object. The medical device for removing the object in the biological lumen has a drive shaft, a cutting portion, a first housing that accommodates the drive shaft to be rotatable, a second housing that is rotatable with respect to the first housing, and a support portion that supports the first housing and the second housing. The second housing and the support portion relatively move along an axis to restrict relative rotation of the first housing and the second housing. The support portion supports the second housing to be rotatable around the axis, and restricts a relative movement and a relative inclination of the second housing and the support portion in a direction intersecting with the axis.

Abstract: A medical device for removing an object within a living body lumen includes a rotatable tubular driven shaft having a leading-out hole opening in a proximal portion of the driven shaft, a cutting unit disposed on a distal side of the driven shaft, the cutting unit cutting an object while rotating together with the driven shaft, and a suction tubular body having a distal portion and a proximal portion, the distal portion of the suction tubular body being located within the driven shaft, the proximal portion of the suction tubular body being located outside the driven shaft and extending in a direction of separating from the driven shaft outward in a radial direction of the driven shaft.

Abstract: A medical device is disclosed that can help prevent a guide wire from coming into contact with a rotating body in the middle of performing a treatment and achieves improvement in the efficiency of cutting an object by the rotating body. The medical device has a sheath that is insertable into a body lumen, a rotatable hollow rotating body that is disposed to protrude toward a distal side of the sheath, and guide wire lumens into which a guide wire w is insertable in parallel with the sheath. A distal surface of the rotating body has corrugated portions.

Abstract: A medical device is disclosed that can help prevent an object existing in a body lumen from clogging a lumen of an elongated member. The medical device including an elongated member having a lumen extending in an axial direction; an insertion member inserted in the lumen of the elongated member on a distal side of the lumen; and a breaking member fixed on an inner surface of the elongated member such that a gap is formed between the insertion member and the breaking member in the lumen of the elongated member on the distal side, and wherein the breaking member exerts a shearing force to the object by rotating relative to the insertion member while the object is between the insertion member and the breaking member.

Abstract: A medical device for removing an intravascular thrombus includes: a rotatable tubular driving shaft in which a spiral-shaped carrier is provided on an inner surface thereof; a cutting part that is provided on a distal side of the driving shaft and cuts the thrombus; and an elongated resistive body that is disposed in a lumen of the driving shaft and can be rotated relative to the driving shaft.

Abstract: A medical device to effectively remove an object, like an intravascular thrombus, in a body lumen includes: a rotatable tubular driving shaft; a cutting part that is provided on a distal side of the driving shaft, rotates together with the driving shaft, and cuts the thrombus; and a second cutting part that is disposed near the distal side of the driving shaft, inward of the cutting part.

Abstract: A medical elongated body is disclosed that suppresses elongation in an axial direction while maintaining high flexibility and has high torque transmission capability even in a bent state. The medical elongated body includes a tube shaped body. The tube shaped body has a slit extending in a spiral shape while meandering, the slit is formed from a pair of a first opposing surface and a second opposing surface, the first opposing surface forms a first convex portion, the first convex portion has a first wide portion having a width wider in a circumferential direction Y, the second opposing surface forms a first concave portion which surrounds and accommodates the first wide portion, the first convex portion has a first plane portion and a first side portion connected to both end portions, and in a circumferential developed view, the first side portion and the first plane portion have tangential discontinuity.

Abstract: To provide a catheter tray that is compact, can reduce costs, can reduce the amount of garbage on the hospital or other catheter user side, and can suppress curling of the catheter. A proximal portion 90 of a catheter 9 is held by a proximal holding portion 11 of a catheter tray 10. A wound body 93 is obtained by winding a flexible shaft 91 of the catheter 9, and a second portion 93b other than a first portion 93a in a circumferential direction of the wound body 93 is allowed to protrude while holding the first portion 93a by the winding holding portion 20 of the catheter tray 10.

Abstract: A medical device has a rotatable drive shaft, a rotary body that includes a cutting edge for applying a cutting force to a stenosed site, and that is disposed on a distal side of the drive shaft so as to be rotated in conjunction with rotation of the drive shaft, a switching portion whose distal end is disposed at a position protruding from the cutting edge, and a holding portion that holds the switching portion so as to move the switching portion on the same plane as the cutting edge or to a position away from the stenosed site beyond the cutting edge in accordance with a pushing force, when the switching portion is pushed against the stenosed site.

Abstract: A medical device has a rotatable drive shaft, a rotary body whose distal end includes a cutting edge for applying a cutting force to a stenosed site, and that is disposed on a distal side of the drive shaft so as to be rotated in conjunction with rotation of the drive shaft, and a distal member disposed in the rotary body. The distal member has a support portion extending to a distal side beyond a distal end of the rotary body, and configured to be capable of supporting the rotary body with respect to a blood vessel. The support portion is configured so that a distance from the rotary body is variable in a first direction (height direction) in which the rotary body is moved close to the stenosed site.

Abstract: A method for treatment of chronic obstructive pulmonary disease includes occluding at least one of a bronchial tube and emphysema, and deciding whether or not a bypass has been formed by the occlusion.

Abstract: A fibrosis-causing agent is highly effective in the fibrosis of tissues. The fibrosis-causing agent contains a fibrosis inducer and a fibrosis promoter. A fibrosis-causing agent dosage form and a method of administering the fibrosis-causing agent is also disclosed.

Abstract: A flexible tube assembly according to the present disclosure includes a multiple tube having at least a first tubular member that has an elongated shape and is hollow and a second tubular member that has an elongated shape and is disposed inside the first tubular member in such a manner as to be capable of advancing and retreating relative to the first tubular member; and a hand operation unit that is provided on a proximal side of the multiple tube and operates at least the first tubular member and the second tubular member.

Abstract: An elongated member which is deflectable and hollow and which is configured for deflection that follows the shape of a biological organ for smooth movement within the organ. The elongated member includes: an operating member configured to deflect the elongated member or deform the elongated member into a linear state; and a deflection mechanism at least including a guide portion having a grooved portion formed thereon, an engaging portion engageable with the grooved portion and a supporting portion configured to support the engaging portion for relative movement on the guide portion; a gap being formed between the guide portion and the engaging portion so as to allow movement of the engaging portion in the grooved portion.

Abstract: A fibrosis-causing agent is highly effective in the fibrosis of tissues. The fibrosis-causing agent contains a fibrosis inducer and a fibrosis promoter. A fibrosis-causing agent dosage form and a method of administering the fibrosis-causing agent is also disclosed.

Abstract: [Object] It is an object of the present invention to provide a catheter for forming a biological tissue holding member by which a body lumen can be maintained in a dilated state even after a procedure of dilating a target part of the body lumen.

Abstract: A method of manufacturing a balloon catheter involves applying a first application liquid, which contains a hydrophilic coating material, to the outer periphery of a balloon which is disposed on an elongated catheter and is held in an expanded state; folding the balloon; and applying a second application liquid, which contains the hydrophilic coating material, to the balloon with the balloon folded.

Abstract: The invention has as its object the provision of a medicine capable of reducing a volume of emphysema-suffering pulmonary alveoli or alveolar sacs by means of a respiratory region volume inhibitor containing a coating film formation as a main component and capable of forming a coating film in a respiratory region, characterized by being used in such a way that the coating film-forming component is administered to an emphysema-suffering pulmonary alveolar parenchyma in a human-respiratory region in an amount of 0.004 to 200 g/application, preferably 0.07 to 20 g/application and more preferably 0.5 to 5 g/application on each occasion.

Abstract: A thrombus aspiration catheter is disclosed which can shear a thrombus and efficiently aspirate the thrombus. When the pressure of the inside of an inner tube is made negative, an outer tube is rotated around an axis relative to the inner tube, and an inner opening portion and an outer opening portion are positioned at an open position at which the inner opening portion and the outer opening portion overlap each other, a thrombus enters the inside of the inner tube through the inner opening portion and the outer opening portion. When the outer tube is further rotated up to a closed position at which the whole outer opening portion does not overlap the inner opening portion, the thrombus is sheared by an edge portion of the inner opening portion and an edge portion of the outer opening portion and into the inside of the inner tube.