Patents by Inventor Yuichi TAKAJO

Yuichi TAKAJO has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11376235
    Abstract: To provide a novel inflammasome inhibitor capable of inhibiting activation of inflammasome, the present inventors newly found that arctigenin reduces the amount of 1L-1? released and the amount of activated caspase-1 upon stimulation with ATP, palmitic acid, MSU and Poly(dA:dT) and thus has an effect of inhibiting inflammasome activation. The present invention provides an inhibitor of inflammasome activation that comprises arctigenin as an active ingredient.
    Type: Grant
    Filed: February 8, 2017
    Date of Patent: July 5, 2022
    Assignee: KRACIE HOLDINGS, LTD.
    Inventors: Shimpei Watanabe, Ayako Arai, Yuichi Takajo, Satoshi Inamasu, Satoshi Yomoda, Akiko Ohno, Yuko Kitahara, Taisaku Kanatani
  • Publication number: 20190099400
    Abstract: To provide a novel inflammasome inhibitor capable of inhibiting activation of inflammasome, the present inventors newly found that arctigenin reduces the amount of 1L-1? released and the amount of activated caspase-1 upon stimulation with ATP, palmitic acid, MSU and Poly(dA:dT) and thus has an effect of inhibiting inflammasome activation. The present invention provides an inhibitor of inflammasome activation that comprises arctigenin as an active ingredient.
    Type: Application
    Filed: February 8, 2017
    Publication date: April 4, 2019
    Applicant: KRACIE HOLDINGS, LTD.
    Inventors: Shimpei WATANABE, Ayako ARAI, Yuichi TAKAJO, Satoshi INAMASU, Satoshi YOMODA, Akiko OHNO, Yuko KITAHARA, Taisaku KANATANI