Abstract: A production method of producing a fluorine-containing olefin by allowing a first olefin represented by the following Formula (1) and a second olefin to react with each other in the presence of a ruthenium compound represented by the following Formula (X) is provided.

Abstract: To provide a nucleic acid excellent in cell membrane permeability and a method for its production. A nucleic acid containing a C2-10 perfluoroalkyl group having from 1 to 5 ether-bonding oxygen atoms between carbon atoms; said nucleic acid wherein said perfluoroalkyl group is directly or indirectly bonded to the 5?- or 3?-end of the nucleic acid, or said perfluoroalkyl group is indirectly introduced between two nucleotides; or a nucleic acid medicine comprising, as an active ingredient, a nucleic acid containing a C2-10 perfluoroalkyl group, which may have from 1 to 5 ether-bonding oxygen atoms between carbon atoms.

Abstract: A method for producing a nitrogen-containing fluorine-containing compound includes a step in which a compound represented by formula (5) is fluorinated to obtain a compound represented by formula (6). R3 is a single bond or a C1-20 divalent organic group. R4 and R5 are each independently a monovalent organic group having an electron-withdrawing group, a C1-20 monovalent hydrocarbon group, or a C2-20 monovalent hydrocarbon group which contains an etheric oxygen atom between carbon atoms. At least one of R4 and R5 is a monovalent organic group having an electron-withdrawing group. R3, R4, and R5 may be bonded to each other to form a divalent organic group or a trivalent organic group. R6 is a C1-20 monovalent organic group. E3 is a divalent organic group. R3F, R4F, R5F, R6F, and E3F are groups formed by fluorinating some or all of hydrogen atoms of R3, R4, R5, R6, and E3.

Abstract: A peptide having a fluoroalkyl group as its side chain and a method for producing, which comprises condensing a compound represented by the formula (6-2) or (6-4), where means that an asymmetric carbon atom has an absolute configuration of S or R, Rf is a C1-30 alkyl group which is substituted with at least two fluorine atoms, and which may further be substituted with a halogen atom other than a fluorine atom (when the C1-30 alkyl group is a C2-30 alkyl group, it may have 1 to 5 etheric oxygen atoms between carbon atoms), and R2 is a protecting group for the amino group, with a fluorinated amino acid having its carboxy group protected, an amino acid having its carboxy group protected, a fluorinated peptide having its C-terminal protected, or a peptide having its C-terminal protected.

Abstract: Provided is an efficient and economical production method of a nitrogen-containing compound. A method for producing a compound represented by the formula R3C(O)CH?CHNR1R2, including reacting a compound represented by the following formula (4) with more than 6-fold moles of a compound represented by the formula NR1R2C(O)H to give a reaction mixture of the compound represented by the formula (4) and the compound represented by the formula NR1R2C(O)H, and reacting the reaction mixture with a compound represented by the formula R3C(O)CH3 by using a basic compound: wherein X is a halogen atom and R1, R2 and R3 are each independently an alkyl group having 1-6 carbon atoms.

Abstract: The invention provides a method capable of more simply and efficiently producing halogen-containing pyrazolecarboxylic acids and intermediates thereof, which are useful as pharmaceutical or agrochemical intermediates, in a manner suitable for industrial production. In particular, the invention provides a method of producing a compound represented by the formula (b), which comprises reacting a compound represented by the formula (a) with a halogenating agent selected from the group consisting of a compound represented by X2 (formula (1)), a compound represented by SOX2 (formula (2)), and a compound represented by SO2X2 (formula (3)) to obtain the compound represented by the formula (b): formula (1) X2 formula (2) SOX2 formula (3) SO2X2 wherein each symbol is as described in the description.

Abstract: The invention relates to a method of producing a compound represented by the formula (a) by reacting a compound represented by the formula (c) with a halogenating agent in a non-aqueous system: wherein R1 is a fluoroalkyl group having 1 to 3 carbon atoms, R2 is a hydrogen atom or an alkyl group having 1 to 6 carbon atoms, R3 is an alkyl group having 1 to 6 carbon atoms, and X is a halogen atom.

Abstract: The invention relates to a production method of pyrazole derivative (6) by reacting compound (5) with an oxidant. wherein R1, R2, R3, X1, X2 and Z1 are as defined herein.

Abstract: The invention relates to a production method of pyrazole derivative (6) by reacting compound (5) with an oxidant. wherein R1, R2, R3, X1, X2 and Z1 are as defined herein.

Abstract: To deprotect an alcoholic hydroxyl group protected by a t-butyldimethylsilyl group without influencing a functional group unstable to an acid. In the presence of a solvent, an alcohol having a hydroxyl group protected by a t-butyldimethylsilyl group is deprotected in the presence of an acid or an acid salt having a pKa of from 1.0 to 3.0 in water.

Abstract: To provide a method for producing a difluoro compound highly selectively in good yield without forming a hardly soluble by-product. An ester compound of the formula (1) is reacted and fluorinated with an electrophilic fluorinating agent in the presence of a basic compound and in the absence of a metal compound reactant to produce a difluoro ester compound of the formula (2). wherein R1 is a C1-30 alkyl group which may have a substituent, etc., and R2 is a C1-30 hydrocarbon group which may have a substituent, or R1 and R2 are bonded to form an alkylene group which forms, together with —C—C(O)—O—, a lactone ring.

Abstract: To deprotect an alcoholic hydroxyl group protected by a t-butyldimethylsilyl group without influencing a functional group unstable to an acid. In the presence of a solvent, an alcohol having a hydroxyl group protected by a t-butyldimethylsilyl group is deprotected in the presence of an acid or an acid salt having a pKa of from 1.0 to 3.0 in water.

Abstract: To provide a curable composition, from which a cured film having a low dielectric constant can be obtained and which is excellent in providing embedding planarity at the time of film formation. A curable composition comprising a fluorinated polyarylene prepolymer (A) having a crosslinkable functional group, and a compound (B) having a molecular weight of from 140 to 5,000, having a crosslinkable functional group and having no fluorine atoms.

Abstract: A useful fluoropolymer excellent in transparency and durability to a short wavelength light (an ArF excimer laser having an irradiation wavelength of 193 nm and a F2 excimer laser having an irradiation wavelength of 157 nm) as e.g. a pellicle material, wherein a polymer (I) to be used for a pellicle membrane and/or an adhesive is a polymer essentially containing the following fluorine atom-containing unit (1), wherein a chain forming the polymer main chain comprises a carbon atom and an etheric oxygen atom, at least one carbon atom forming the main chain is a carbon atom forming a cyclic group, and at least one etheric oxygen atom forming the main chain is an oxygen atom forming no cyclic group.

Abstract: A crosslinkable fluorinated aromatic prepolymer which is capable of forming a cured product having high transparency, a low relative permittivity, high heat resistance, low birefringence and high flexibility, and which is obtained by subjecting a compound (Y-1) having a polymerizable double bond (A) and/or a phenolic hydroxyl group and a compound (Y-2) having a polymerizable double bond (A) and a fluorinated aromatic ring, to a condensation reaction in the presence of a HF-removing agent, with a particular fluorinated aromatic compound (B) and a compound (C) having at least 3 phenolic hydroxyl groups, the respective phenolic hydroxyl groups not being present in the same aromatic ring, and which has polymerizable double bonds (A) and ether bonds and has a number average molecular weight of from 1×103 to 5×105.

Abstract: To provide a crosslinkable fluorinated aromatic prepolymer which is capable of forming a cured product having high transparency, a low relative permittivity, high heat resistance, low birefringence and high flexibility, and its uses.

Abstract: A lens produced from a radial rays-curing material comprises a lens proper portion that serves as an optically effective part of the lens, and a circular flange portion that surrounds the lens proper portion and serves as an optically non-effective part of the lens. The circular flange portion has front and rear surfaces that are different in appearance.

Abstract: It is to provide a useful fluoropolymer excellent in transparency and durability to a short wavelength light (an ArF excimer laser having an irradiation wavelength of 193 nm and a F2 excimer laser having an irradiation wavelength of 157 nm) as e.g. a pellicle material. A pellicle wherein a polymer (I) to be used for a pellicle membrane and/or an adhesive is a polymer essentially containing the following unit (1). The unit (1) is a unit containing a fluorine atom, wherein a chain forming the polymer main chain comprises a carbon atom and an etheric oxygen atom, at least one carbon atom forming the main chain is a carbon atom forming a cyclic group, and at least one etheric oxygen atom forming the main chain is an oxygen atom forming no cyclic group.