Patents by Inventor Yuichiro ONODERA

Yuichiro ONODERA has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11357819
    Abstract: The present invention is a cytocidal agent including a peptide consisting of an amino acid sequence represented by SEQ ID NO: 1 and a site selectively binding to a target molecule, in which the peptide consisting of an amino acid sequence represented by SEQ ID NO: 1 is a peptide exclusively consisting of L-amino acids, a peptide in which, in amino acid sequences represented by SEQ ID NO: 1, the first to the 14th amino acids are D-amino acids, and the 15th to 19th amino acids are L-amino acids, a peptide in which, in amino acid sequences represented by SEQ ID NO: 1, the first to 14th amino acids are L-amino acids, and the 15th to the 19th amino acids are D-amino acids, or a peptide exclusively consisting of D-amino acids.
    Type: Grant
    Filed: August 23, 2018
    Date of Patent: June 14, 2022
    Assignee: FUJITA ACADEMY
    Inventors: Kazuhiro Sugihara, Naohiro Kanayama, Yuichiro Onodera, Toshiaki Shibata, Michiko Fukuda, Motohiro Nonaka
  • Patent number: 11191804
    Abstract: An object of the present invention is to provide a peptide drug that is able to selectively induce apoptosis in target cells. The present invention is a cytocidal agent containing a fusion peptide of an endosome escape peptide and an apoptosis-inducing peptide, which consists of an amino acid sequence represented by SEQ ID NO: 1, and the said cytocidal agent as a therapeutic agent for a disease caused by abnormal proliferation of cells.
    Type: Grant
    Filed: December 28, 2018
    Date of Patent: December 7, 2021
    Assignee: FUJITA ACADEMY
    Inventors: Kazuhiro Sugihara, Naohiro Kanayama, Toshiaki Shibata, Yuichiro Onodera
  • Publication number: 20200330549
    Abstract: An object of the present invention is to provide a peptide drug that is able to selectively induce apoptosis in target cells. The present invention is a cytocidal agent containing a fusion peptide of an endosome escape peptide and an apoptosis-inducing peptide, which consists of an amino acid sequence represented by SEQ ID NO: 1, and the said cytocidal agent as a therapeutic agent for a disease caused by abnormal proliferation of cells.
    Type: Application
    Filed: December 28, 2018
    Publication date: October 22, 2020
    Inventors: Kazuhiro SUGIHARA, Naohiro KANAYAMA, Toshiaki SHIBATA, Yuichiro ONODERA
  • Publication number: 20200289608
    Abstract: The present invention is a cytocidal agent including a peptide consisting of an amino acid sequence represented by SEQ ID NO: 1 and a site selectively binding to a target molecule, in which the peptide consisting of an amino acid sequence represented by SEQ ID NO: 1 is a peptide exclusively consisting of L-amino acids, a peptide in which, in amino acid sequences represented by SEQ ID NO: 1, the first to the 14 amino acids are D-amino acids, and the 15th to 19th amino acids are L-amino acids, a peptide in which, in amino acid sequences represented by SEQ ID NO: 1, the first to 14th amino acids are L-amino acids, and the 15th to the 1.9th amino acids are D-amino acids, or a peptide exclusively consisting of D-amino acids.
    Type: Application
    Filed: August 23, 2018
    Publication date: September 17, 2020
    Inventors: Kazuhiro SUGIHARA, Naohiro KANAYAMA, Yuichiro ONODERA, Toshiaki SHIBATA, Michiko FUKUDA, Motohiro NONAKA