Abstract: The present invention aims to provide a method for determining breast cancer susceptibility, in which a DNA copy number polymorphism associated with breast cancer susceptibility is identified and determination is made based on an increase or decrease in the DNA copy number polymorphism. The present invention attempts to achieve this by performing microarray assay using the peripheral blood of sporadic breast cancer patients, identifying a DNA copy number polymorphism associated with breast cancer susceptibility in a chromosomal region, detecting the number of copies of the above DNA copy number polymorphism by quantitative PCR, and then determining breast cancer susceptibility based on an increase or decrease in the DNA copy number polymorphism.

Abstract: The purpose of the present invention is to provide a method for detecting even mucin 1 derived from breast cancer, which cannot be detected by a CA15-3 measurement method. The purpose can be achieved by a method for analyzing the mucin 1 having a Sulfo-3Gal?1-3GalNAc-R carbohydrate chain, including: a step of bringing a 3? sulfonated core 1 carbohydrate chain binding probe capable of binding to the Sulfo-3Gal?1-3GalNAc-R carbohydrate chain into contact with a sample to be tested; a step of bringing a 3? sulfonated core 1 carbohydrate chain mucin 1 peptide binding probe capable of binding to the mucin 1 having a Sulfo-3Gal?1-3GalNAc-R carbohydrate chain or a mucin 1 binding probe capable of binding to a mucin 1 into contact with the sample to be tested; and a step of detecting a conjugate of the mucin 1 having a Sulfo-3Gal?1-3GalNAc-R carbohydrate chain and probe.

Abstract: The present invention aims to provide a method for determining breast cancer susceptibility, in which a DNA copy number polymorphism associated with breast cancer susceptibility is identified and determination is made based on an increase or decrease in the DNA copy number polymorphism. The present invention attempts to achieve this by performing microarray assay using the peripheral blood of sporadic breast cancer patients, identifying a DNA copy number polymorphism associated with breast cancer susceptibility in a chromosomal region, detecting the number of copies of the above DNA copy number polymorphism by quantitative PCR, and then determining breast cancer susceptibility based on an increase or decrease in the DNA copy number polymorphism.

Abstract: The object of the present invention is to provide a clinical marker capable of distinguishing breast cancer from interstitial pneumonia; and a clinical marker for detecting malignancy or progress level of breast cancer, and for monitoring effects of the treatment of breast cancer. The object can be solved by a method for analyzing mucin 1 having Sia?2-8Sia?2-3Gal?-R, characterized by comprising the step of bringing a first probe specifically binding to a mucin 1 having Sia?2-8Sia?2-3Gal?-R into contact with a sample to be tested.

Abstract: Disclosed is a method for determining the presence or absence of a colorectal tumor, specifically colorectal cancer or colorectal adenoma, with high sensitivity and high specificity by employing the methylation of DNA as a measure. Also disclosed is a kit for carrying out the method. Specifically, measurement is made on the degree of methylation of one or more CpG sequences contained in the region lying between positions -477 to -747, more preferably a CGCG sequence contained in the region lying between positions -688 to -691, in TWIST1 gene (Homo sapiens twist homolog 1; Drosophila gene) located on the genome sequence of a test cell.

Abstract: A monoclonal antibody specifically reactive to a human adenocarcinoma cell, which is obtainable by cultivating a fused cell obtained by fusing a mammalian animal cell, immunized with a human adenocarcinoma cell, with a myeloma cell.

Abstract: A method for electrolytic coloring of anodized aluminum or aluminum alloys in an electrolyte containing metal salts is disclosed, in which the aluminum or aluminum alloy is preliminarily treated in an electrolyte by applying a voltage of substantially positive voltage wave form and, thereafter, the electrolytic coloring is carried out in the same electrolyte by applying an asymmetrical alternating current voltage that the positive voltage is smaller than the negative voltage.

Abstract: Process for reclaiming stannous ion by reducing the same in an electrolyte to stannic ion through a simple operation in a short period of time, which comprises the steps of preparing the electrolyte in an acidic range as required and then adding metallic tin to the electrolyte and heating the mixture to at least 80.degree. C., in order to reduce the stannous ion oxidized in the electrolyte containing tin salt to obtain a stable electrolyte treated product. This process may be utilized particularly for effectively reducing and reclaiming an electrolyte which contains tin salt used for electrolytically coloring aluminum.