Patents by Inventor Yuji Hirowatari

Yuji Hirowatari has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20120122242
    Abstract: A method for assessing arteriosclerosis comprising measuring the serotonin level in whole blood, serum or platelet-rich plasma and rating the serotonin level on such a scale that the lower it is, the more serious the arteriosclerosis is.
    Type: Application
    Filed: January 26, 2012
    Publication date: May 17, 2012
    Applicants: KANSAI MEDICAL UNIVERSITY, TOSOH CORPOPRATION
    Inventors: Yuji Hirowatari, Katsuko Hara, Hakuo Takahashi
  • Patent number: 8142995
    Abstract: A method for assessing arteriosclerosis comprising measuring the serotonin level in whole blood, serum or platelet-rich plasma and rating the serotonin level on such a scale that the lower it is, the more serious the arteriosclerosis is.
    Type: Grant
    Filed: March 11, 2008
    Date of Patent: March 27, 2012
    Assignees: Tosoh Corporation, Kansai Medical University
    Inventors: Yuji Hirowatari, Katsuko Hara, Hakuo Takahashi
  • Publication number: 20120058549
    Abstract: A method of analyzing vitamin E components in a lipoproteinby subjecting a lipoprotein-containing sample to ion exchange chromatography to separate the lipoprotein, reacting the separated lipoprotein to a pretreating solution containing an organic solvent and a surfactant to liberate vitamin E components, and then subjecting the liberated vitamin E components to reverse phase chromatography. Also described is a method of judging various pathological conditions such as the pathological conditions of diabetes, the risks of coronary artery diseases, and the pathological conditions of myocardial infarction using levels of vitamin E components in the lipoprotein as an index.
    Type: Application
    Filed: November 4, 2011
    Publication date: March 8, 2012
    Applicant: TOSOH CORPORATION
    Inventor: Yuji HIROWATARI
  • Patent number: 8076145
    Abstract: A method of analyzing vitamin E components in a lipoprotein by subjecting a lipoprotein-containing sample to ion exchange chromatography to separate the lipoprotein, reacting the separated lipoprotein to a pretreating solution containing an organic solvent and a surfactant to liberate vitamin E components, and then subjecting the liberated vitamin E components to reverse phase chromatography. Also described is a method of judging various pathological conditions such as the pathological conditions of diabetes, the risks of coronary artery diseases, and the pathological conditions of myocardial infarction using levels of vitamin E components in the lipoprotein as an index.
    Type: Grant
    Filed: April 15, 2011
    Date of Patent: December 13, 2011
    Assignee: Tosoh Corporation
    Inventor: Yuji Hirowatari
  • Publication number: 20110195511
    Abstract: A method of analyzing vitamin E components in a Lipoprotein by subjecting a lipoprotein-containing sample to ion exchange chromatography to separate the lipoprotein, reacting the separated lipoprotein to a pretreating solution containing an organic solvent and a surfactant to liberate vitamin E components, and then subjecting the liberated vitamin E components to reverse phase chromatography. Also described is a method of judging various pathological conditions such as the pathological conditions of diabetes, the risks of coronary artery diseases, and the pathological conditions of myocardial infarction using levels of vitamin E components in the lipoprotein as an index.
    Type: Application
    Filed: April 15, 2011
    Publication date: August 11, 2011
    Applicant: TOSOH CORPORATION
    Inventor: Yuji Hirowatari
  • Patent number: 7981683
    Abstract: A method of analyzing vitamin E components in a lipoproteinby subjecting a lipoprotein-containing sample to ion exchange chromatography to separate the lipoprotein, reacting the separated lipoprotein to a pretreating solution containing an organic solvent and a surfactant to liberate vitamin E components, and then subjecting the liberated vitamin E components to reverse phase chromatography. Also described is a method of judging various pathological conditions such as the pathological conditions of diabetes, the risks of coronary artery diseases, and the pathological conditions of myocardial infarction using levels of vitamin E components in the lipoprotein as an index.
    Type: Grant
    Filed: May 25, 2007
    Date of Patent: July 19, 2011
    Assignee: Tosoh Corporation
    Inventor: Yuji Hirowatari
  • Publication number: 20090246878
    Abstract: A method of analyzing vitamin E components in a lipoprotein, which comprises subjecting a lipoprotein-containing sample to ion exchange chromatography to separate the lipoprotein, reacting the separated lipoprotein to a pretreating solution containing an organic solvent and a surfactant to liberate vitamin E components, and then subjecting the liberated vitamin E components to reverse phase chromatography, and a method of judging various pathological conditions such as the pathological conditions of diabetes, the risks of coronary artery diseases, and the pathological conditions of myocardial infarction using levels of vitamin E components in the lipoprotein as an index.
    Type: Application
    Filed: May 25, 2007
    Publication date: October 1, 2009
    Applicant: TOSOH CORPORATION
    Inventor: Yuji Hirowatari
  • Publication number: 20080160562
    Abstract: A method for assessing arteriosclerosis comprising measuring the serotonin level in whole blood, serum or platelet-rich plasma and rating the serotonin level on such a scale that the lower it is, the more serious the arteriosclerosis is.
    Type: Application
    Filed: March 11, 2008
    Publication date: July 3, 2008
    Applicants: TOSOH CORPORATION, Kansai Medical University
    Inventors: Yuji Hirowatari, Katsuko Hara, Hakuo Takahashi
  • Patent number: 7262060
    Abstract: A method for assessing nicotine dependence, which involves measuring a whole blood, serum or platelet-rich plasma serotonin level and rating the whole blood, serum or platelet-rich plasma serotonin level on such a scale that the higher it is, the higher nicotine dependence is.
    Type: Grant
    Filed: October 26, 2004
    Date of Patent: August 28, 2007
    Assignee: Tosoh Corporation
    Inventors: Yuji Hirowatari, Katsuko Hara, Hakuo Takahashi
  • Publication number: 20060199268
    Abstract: A method for assessing arteriosclerosis comprising measuring the serotonin level in whole blood, serum or platelet-rich plasma and rating the serotonin level on such a scale that the lower it is, the more serious the arteriosclerosis is.
    Type: Application
    Filed: March 6, 2006
    Publication date: September 7, 2006
    Inventors: Yuji Hirowatari, Katsuko Hara, Hakuo Takahashi
  • Publication number: 20050112771
    Abstract: A method for assessing nicotine dependence, which comprises measuring a whole blood, serum or platelet-rich plasma serotonin level and rating the whole blood, serum or platelet-rich plasma serotonin level on such a scale that the higher it is, the higher nicotine dependence is.
    Type: Application
    Filed: October 26, 2004
    Publication date: May 26, 2005
    Inventors: Yuji Hirowatari, Katsuko Hara, Hakuo Takahashi
  • Patent number: 6485753
    Abstract: A method for diagnosing vascular endothelial injury, which comprises measuring the serotonin level in a plasma sample.
    Type: Grant
    Filed: August 15, 2001
    Date of Patent: November 26, 2002
    Assignee: Tosoh Corporation
    Inventors: Yuji Hirowatari, Hakuo Takahashi, Katsuko Hara
  • Publication number: 20020052017
    Abstract: A method for diagnosing vascular endothelial injury, which comprises measuring the serotonin level in a plasma sample.
    Type: Application
    Filed: August 15, 2001
    Publication date: May 2, 2002
    Applicant: TOSOH CORPORATION
    Inventors: Yuji Hirowatari, Hakuo Takahashi, Katsuko Hara