Abstract: A prevention switching device is provided. The apparatus includes a switching circuit and a controller. The switching circuit includes a switching relay capable of switching a connection destination of a first power conversion circuit other than a second power conversion circuit among the plurality of power conversion circuits between a phase corresponding to the first power conversion circuit and a certain phase of the external power supply. The second power conversion circuit corresponds to the certain phase of the external power supply. The controller controls an operation of the switching relay at a zero-crossing time of an AC voltage estimated based on the AC voltage.

Abstract: A prevention switching device is provided. The apparatus includes a switching circuit and a controller. The switching circuit includes a switching relay capable of switching a connection destination of a first power conversion circuit other than a second power conversion circuit among the plurality of power conversion circuits between a phase corresponding to the first power conversion circuit and a certain phase of the external power supply. The second power conversion circuit corresponds to the certain phase of the external power supply. The controller controls an operation of the switching relay at a zero-crossing time of an AC voltage estimated based on the AC voltage.

Abstract: The present invention provides a method for efficiently screening a substance which promotes or inhibits an active transfer of ABC protein, characterized in that, (a) ABC protein gene is introduced into a yeast cell having a high drug sensitivity to prepare a transformed yeast cell where ABC protein is expressed in cell membrane site, (b) the transformed yeast cell is incubated in the presence of a test substance and a substance which is subjected to an active transfer outside the cell by ABC protein existing in the cell membrane site and has a cytotoxicity to the yeast cell and (c) degree of the growth of said transformed yeast cell is compared with the case where incubation is carried out in the absence of the test substance.

Abstract: A process for manufacturing beer having a reduced content of purine compounds by using wort having a reduced content of purine nucleosides as a result of decomposing purine nucleosides into purine bases by using nucleoside phosphorylase or nucleosidase, or decomposing purine nucleosides into purine bases during fermentation and having the purine bases metabolized by yeast.

Abstract: A protein derived from a strain of methylotrophic yeast which has a protein disulfide isomerase activity having the amino acid sequence as set forth in SEQ ID No. 1, or protein in which the amino acid sequence has been modified by deletion or addition of one or a few amino acids, or substitution with other amino acid(s) and which has a protein disulfide isomerase activity; and a process for production thereof.

Abstract: The present invention relates to a novel proteinase inhibitor useful as a medicine or pesticides and a gene coding for the inhibitor. A proteinase inhibitor (Kexstatin) having inhibitory activity against Kex2 proteinase family enzymes and having a molecular weight of 11,500; a gene coding for Kexstatin; and a method for producing Kexstatin using a microorganism belonging to the genus Streptomyces or transformed with Kexstatin gene are disclosed.

Abstract: Described herein are a novel heat-resistant .beta.-galactosyltransferase, a production process of the enzyme and a utilization method of the enzyme. The enzyme is produced preferably by produced by a microorganism belonging to the family of Actinomycetaceae, which may be selected from fungi belonging to the genus Saccharopolyspora, the genus Thermomonospora or the genus Thermoactinomvces.

Abstract: The present invention relates to an expression vector which is induced by methanol and/or glycerol utilizing an alcohol oxidase gene of a methylotrophic yeast; a recombinant methylotrophic yeast containing said vector and capable of accumulating a significantly high amount of an expression product of a heterologous gene; and a method for producing useful products utilizing said recombinant.The expression vector is constructed by utilizing the promoter and terminator of an alcohol oxidase gene of methylotrophic yeast. Further, a significantly high amount of adenylate kinase, cytochrome C552 or peroxidase is produced by using said expression vector.

Abstract: A collagenase gene derived from bacteria of the species Vibrio alginolyticus is disclosed. A recombinant vector containing the gene, a host cell transformed with a plasmid containing the gene and a process for the production of a collagenase by using the host cells are also disclosed.

Abstract: A yeast host which can express P-glycoprotein, i.e., the product of MDR-related gene, in the cell membrane in the same state as observed in multidrug resistant cells produced by connecting the MDR-related gene which carries multidrug resistance to a yeast expression vector and transforming the yeast with said recombinant vector; a cell membrane fraction containing a substantial amount of P-glycoprotein produced by said yeast and a process for the preparation thereof; and a recombinant vector for expressing the MDR-related gene in a yeast host.

Abstract: Fusaric acid resistant genes derived from fusaric acid decomposing or detoxifying microorganisms such as Pseudomonas cepacia and Klebsiella oxytoca are described. Also described are DNA fragments and plasmids, which comprise such fusaric acid resistant genes. Host cells comprising such plasmids are also described.

Abstract: A peroxidase gene derived from Arthromyse ramosus and its cloning and expression in E. coli and yeast is disclosed. The peroxidase encoded by this gene is not-specific and does not contain isozymes and hence is suitable as a diagnostic reagent or as a marker enzyme in enzyme innunoassays.

Abstract: Described herein are a novel heat-resistant .beta.-galactosyltransferase, a production process of the enzyme and a utilization method of the enzyme. The enzyme is produced preferably by produced by a microorganism belonging to the family of Actinomycetaceae, which may be selected from fungi belonging to the genus Saccharopolyspora, the genus Thermomonospora or the genus Thermoactinomyces.

Abstract: Described herein are a novel heat-resistant .beta.-galactosyltransferase, a production process of the enzyme and a utilization method of the enzyme. The enzyme is produced preferably by produced by a microorganism belonging to the family of Actinomycetaceae, which may be selected from fungi belonging to the genus Saccharopolyspora, the genus Thermomonospora or the genus Thermoactinomyces.

Abstract: This invention provides a process for producing ethanol from a starchy material, wherein the starchy material is simultaneously subjected to saccharification and subsequent fermentation by use of a yeast host which has been transformed by an expressible recombinant vector comprising a glucoamylase gene derived from a fungus of the genus Rhizopus.

Abstract: The present invention relates to the Rhizopus derived glucoamylase gene, a novel recombinant vector comprising said gene, and a microorganism transformed by said vector, as well as a process for reproducing Rhizopus glucoamylase by cultivating the transformed microorganism, especially yeast, in a liquid medium.