Abstract: Provided is an anti-Henipavirus monoclonal antibody having broad spectrum neutralization activity, wherein the antibody comprises a macaque variable region and a human constant region. The antibody of the present invention has good binding activity to both Nipah virus glycoprotein G and Hendra virus glycoprotein G, can effectively neutralize Nipahpseudovirus and Hendra pseudovirus, and can be used for preparing drugs for treating Henipavirus diseases.

Abstract: Disclosed is a monoclonal antibody 2G1 against an Ebola glycoprotein GP2 subunit. The monoclonal antibody has binding activity to EBOV GP, BDBV GP, SUDV GP, and RESTV GP, and can play a neutralizing role.

Abstract: Disclosed in the present invention is an anti-Nipah virus monoclonal antibody having neutralization activity. The antibody consists of a monkey-derived variable region and a human constant region, and both light and heavy chains of the monkey-derived variable region have unique CDR regions. The antibody provided by the present invention has an excellent antigen binding capability, and has good binding activity with Bangladesh Nipah virus and Malaysia Nipah virus glycoprotein G. The antibody can effectively neutralize the Nipahpseudovirus. Moreover, the neutralization activity of the antibody is enhanced as the concentration of the antibody increases, and nearly 100% neutralization of the Nipahpseudovirus can be achieved at a concentration of 1 ?g/mL. Also disclosed in the present invention is an application of the monoclonal antibody against the Nipah virus glycoprotein G in preparation of a Nipah virus treatment drug.

Abstract: Provided is a traditional Chinese herbal composition for treating pulmonary nodules, a preparation method thereof, and a honeyed pill. The composition comprises: 30 parts by weight of Ziziphi Spinosae Semen, 20-30 parts by weight of Rehmaniae Radix, 30 parts by weight of Trichosanthis Radix, 40-50 parts by weight of Paeoniae Radix Alba, 30 parts by weight of Coicis Semen Preparata, 20 parts by weight of Ginseng Radix et Rhizoma, 10 parts by weight of Olibanum, 10 parts by weight of Myrrha, 20-30 parts by weight of Testudinis Carapax et Plastrum Preparata Cum Aceto, 20-30 parts by weight of Trionycis Carapax Preparata Cum Aceto, 30 parts by weight ofAgrimoniae Herba, 10-20 parts by weight ofAlpiniae Oxyphyllae Fructus, 5 parts by weight of Toosendan Fructus, 20 parts by weight of Poria, 10 parts by weight of Platycodonis Radix, and 10 parts by weight of Polygalae Radix.

Abstract: The present invention provides an anti-TrkA antibody or an antigen-binding fragment thereof, a preparation method, and an application thereof. The present invention also provides an isolated polynucleotide encoding the anti-TrkA antibody or the antigen-binding fragments thereof, and a vector comprising the isolated polynucleotide. The present invention also provides a use of the antibody or the antigen-binding fragment thereof in the preparation of a drug for treating pain.

Abstract: The present disclosure discloses an image configuration method, device and system, and a storage medium, relating to the technical field of terminal applications. The image configuration method includes: downloading an image configuration table, wherein the image configuration table includes identifiers of images to be adjusted in a terminal application, and links of the images at a server; in response to detecting, via monitoring, a request to load an image, detecting whether or not an identifier of the requested image is present in the image configuration table; and if so, downloading, according to the identifiers of the images and the links of the images at the server in the image configuration table, an adjustment image from the server, and loading the adjustment image.

Abstract: Provided are an anti-NGF antibody or an antigen-binding fragment thereof, a preparation method and an application thereof. Also provided is an isolated polynucleotide encoding the anti-NGF antibody or the antigen-binding fragment thereof, as well as a vector containing the isolated polynucleotide. Also provided is use of the antibody or the antigen-binding fragment thereof of the present invention in preparing the medicament for the treatment of NGF-mediated diseases or disorders.