Abstract: The disclosure discloses a strain and method for producing rosmarinic acid, and belongs to the technical field of bioengineering. The disclosure constructs a recombinant cell or a combination of recombinant cells expressing 4-coumarate: CoA ligase, rosmarinic acid synthase, polyphosphate kinase 2-I (PPK2-I) and polyphosphate kinase 2-II (PPK2-II), and utilizes the recombinant cell or the combination of recombinant cells to catalyze Danshensu and caffeic acid for synthesizing rosmarinic acid. The disclosure has good industrial application prospects.

Abstract: A method for filling carbide blades in cutter head by using a carbide blade cutter head filling device. The carbide blade cutter head filling device includes a feeding unit, a storage unit, a loading unit and a discharging unit which are arranged successively. The output end of the feeding unit is matched with the input end of the storage unit through the guide mechanism. The output end of the storage unit faces a conveying tray of the loading unit. The conveying tray is provided with a plurality of group of transition holes for accommodating blades. A receiving mechanism for accommodating a cutter head is arranged below the falling pull plate of the discharging unit. The falling pull plate adjusts the communication and isolation between the transition hole and the cutter head in the receiving mechanism by changing the relative position of the falling pull plate and the transition hole.

Abstract: Recombinant protein of GPER is provided. The recombinant protein has the biological activity of G protein-coupled estrogen receptor.

Abstract: Interleaved infrastructure can interleave fragment execution during query compilation. For example, compilation can be paused, and a plan fragment is executed. The results of the plan fragment can be fed back into the compiler, which can then restart the compilation and modify the compilation based on the results of the plan fragment execution. The interleaved workflow provides a flexible, robust infrastructure, which can enable and improve a variety of database features and query optimizations.

Abstract: Embodiments automatically assess, e.g., quantify dimensions of, cracks in real-world objects. Amongst other examples, such functionality can be used to identify structural problems in bridges and buildings. An example implementation maps pixels in an image of a real-world object to corresponding points in point cloud data of the real-world object. In turn, a patch in the image data that includes a crack is identified by processing, using a classifier, the pixels with the corresponding points mapped. Pixels in the patch that correspond to the crack are then identified based on one or more features of the image. Real-world dimensions of the crack are determined using the identified pixels in the patch corresponding to the crack.

Abstract: Embodiments generate finite element meshes (FEMs) representing real-world objects. An example embodiment partitions point cloud data of a real-world object into groups of points where each group corresponds to a component of the real-world object. In turn, such an embodiment generates a respective geometric representation of each group of points and generates a respective FEM of each respective geometric representation generated. The generated FEMs are combined to create a FEM representing the real-world object. Such functionality can be used to build FEMs of as built real-world objects, such as bridges and buildings. These FEMs can, in turn, be used in simulations to determine behavior of the as-built real-world objects and/or determine design changes.

Abstract: Provided is a tetravalent homodimeric bispecific antibody molecule simultaneously targeting an immune effector cell antigen CD3 and a tumor-associated antigen, wherein the bispecific antibody molecule contains, in order from N-terminus to C-terminus, a first single chain Fv, a second single chain Fv and a Fc fragment; wherein the first single chain Fv can specifically bind to the tumor-associated antigen, the second single chain Fv can specifically bind to CD3, and the first and the second single chain Fvs are connected by a linker peptide, while the second single chain Fv and the Fc fragment are directly connected or connected by a linker peptide; and the Fc fragment does not have effector functions such as CDC, ADCC and ADCP.