Abstract: Recombinant protein of GPER is provided. The recombinant protein has the biological activity of G protein-coupled estrogen receptor.

Abstract: Embodiments automatically assess, e.g., quantify dimensions of, cracks in real-world objects. Amongst other examples, such functionality can be used to identify structural problems in bridges and buildings. An example implementation maps pixels in an image of a real-world object to corresponding points in point cloud data of the real-world object. In turn, a patch in the image data that includes a crack is identified by processing, using a classifier, the pixels with the corresponding points mapped. Pixels in the patch that correspond to the crack are then identified based on one or more features of the image. Real-world dimensions of the crack are determined using the identified pixels in the patch corresponding to the crack.

Abstract: Embodiments generate finite element meshes (FEMs) representing real-world objects. An example embodiment partitions point cloud data of a real-world object into groups of points where each group corresponds to a component of the real-world object. In turn, such an embodiment generates a respective geometric representation of each group of points and generates a respective FEM of each respective geometric representation generated. The generated FEMs are combined to create a FEM representing the real-world object. Such functionality can be used to build FEMs of as built real-world objects, such as bridges and buildings. These FEMs can, in turn, be used in simulations to determine behavior of the as-built real-world objects and/or determine design changes.

Abstract: Provided is a tetravalent homodimeric bispecific antibody molecule simultaneously targeting an immune effector cell antigen CD3 and a tumor-associated antigen, wherein the bispecific antibody molecule contains, in order from N-terminus to C-terminus, a first single chain Fv, a second single chain Fv and a Fc fragment; wherein the first single chain Fv can specifically bind to the tumor-associated antigen, the second single chain Fv can specifically bind to CD3, and the first and the second single chain Fvs are connected by a linker peptide, while the second single chain Fv and the Fc fragment are directly connected or connected by a linker peptide; and the Fc fragment does not have effector functions such as CDC, ADCC and ADCP.