Patents by Inventor Yujing Yuan

Yujing Yuan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 12180303
    Abstract: Disclosed are an antibody that can bind to human MASP-2, a preparation method therefor and an application thereof. The anti-human MASP-2 antibody of the present invention can specifically bind to human MASP-2, has good biological activity of inhibiting the cleavage of C4 and the generation of C3b, and can be applied in the treatment of MASP-2 related diseases, such as IgA nephropathy.
    Type: Grant
    Filed: October 13, 2023
    Date of Patent: December 31, 2024
    Assignee: SHANGHAI MABGEEK BIOTECH. CO., LTD.
    Inventors: Yipan Wu, Wei Dang, Chenghai Zhang, Lingqiao Zhu, Jinlin Guo, Yujing Yuan, Qiuling Zou, Yang Wang, Shun Hu
  • Publication number: 20240262904
    Abstract: Disclosed in the present invention are an antibody capable of binding to human thymic stromal lymphopoietin (hTSLP), a preparation method therefor and an application thereof. The anti-hTSLP antibody of the present invention can specifically bind to a hTSLP receptor, has a good effect of inhibiting the secretion of TARC by PBMC, and can be applied to the treatment of TSLP-related diseases, such as immune-mediated inflammatory diseases.
    Type: Application
    Filed: October 19, 2021
    Publication date: August 8, 2024
    Inventors: Jinlin GUO, Yujing YUAN, Wei DANG, Yipan WU, Lingqiao ZHU, Chenghai ZHANG, Qiuling ZOU, Zhike LI, Yang WANG
  • Publication number: 20240190979
    Abstract: The present invention discloses an antibody capable of binding to human interleukin 4 receptor alpha (hIL-4R alpha) and a preparation method and application thereof. The anti-hIL-4R alpha antibody can specifically bind to hIL-4R alpha, has good effects for inhibiting IL-4 and IL-13-induced cell line proliferation and the like, and can be applied to treatment of IL-4R alpha related diseases, such as immune-mediated inflammatory diseases.
    Type: Application
    Filed: February 21, 2024
    Publication date: June 13, 2024
    Inventors: Chenghai Zhang, Jinlin Guo, Yujing Yuan
  • Patent number: 11939387
    Abstract: The present invention discloses an antibody capable of binding to human interleukin 4 receptor alpha (hIL-4R alpha) and a preparation method and application thereof. The anti-hIL-4R alpha antibody can specifically bind to hIL-4R alpha, has good effects for inhibiting IL-4 and IL-13-induced cell line proliferation and the like, and can be applied to treatment of IL-4R alpha related diseases, such as immune-mediated inflammatory diseases.
    Type: Grant
    Filed: October 17, 2022
    Date of Patent: March 26, 2024
    Assignee: SHANGHAI MABGEEK BIOTECH. CO., LTD
    Inventors: Chenghai Zhang, Jinlin Guo, Yujing Yuan
  • Publication number: 20240043563
    Abstract: Disclosed are an antibody that can bind to human MASP-2, a preparation method therefor and an application thereof. The anti-human MASP-2 antibody of the present invention can specifically bind to human MASP-2, has good biological activity of inhibiting the cleavage of C4 and the generation of C3b, and can be applied in the treatment of MASP-2 related diseases, such as IgA nephropathy.
    Type: Application
    Filed: October 13, 2023
    Publication date: February 8, 2024
    Inventors: Yipan WU, Wei DANG, Chenghai ZHANG, Lingqiao ZHU, Jinlin GUO, Yujing YUAN, Qiuling ZOU, Yang WANG, Shun HU
  • Publication number: 20230203172
    Abstract: The present invention discloses an antibody capable of binding to human interleukin 4 receptor alpha (hIL-4R alpha) and a preparation method and application thereof. The anti-hIL-4R alpha antibody can specifically bind to hIL-4R alpha, has good effects for inhibiting IL-4 and IL-13-induced cell line proliferation and the like, and can be applied to treatment of IL-4R alpha related diseases, such as immune-mediated inflammatory diseases.
    Type: Application
    Filed: October 17, 2022
    Publication date: June 29, 2023
    Inventors: Chenghai Zhang, Jinlin Guo, Yujing Yuan