Abstract: Provided in the present disclosure is crystal form I of compound 1, and a preparation method thereof and the use thereof.

Abstract: Provided in the present disclosure is crystal form I of compound 1, and a preparation method thereof and the use thereof.

Abstract: A five-membered heterocyclic amide WNT pathway inhibitor having the following general structural formula: The five-membered heterocyclic amide WNT pathway inhibitor has a remarkable anti-tumor activity based on a target-based rational drug design, and can be used for the development of a new generation of Wnt pathway inhibitors, and has a great clinical application value and considerable market potential.

Abstract: The present invention discloses a compound for regulating protein kinase activity and used for treating or preventing diseases associated with protein kinases. Specifically, the present invention relates to a benzofuran pyrazole amine protein kinase inhibitor which belongs to compounds that regulate anaplastic lymphoma kinase (ALK), and provides a method of preparing such a compound and a pharmaceutical use of such a compound in the treatment or prevention of diseases associated with ALK. The inhibitor can solve the problem of the drug resistance of the first generation and the second generation of ALK inhibitors.

Abstract: The present invention discloses a compound for regulating protein kinase activity and used for treating or preventing diseases associated with protein kinases. Specifically, the present invention relates to a benzofuran pyrazole amine protein kinase inhibitor which belongs to compounds that regulate anaplastic lymphoma kinase (ALK), and provides a method of preparing such a compound and a pharmaceutical use of such a compound in the treatment or prevention of diseases associated with ALK. The inhibitor can solve the problem of the drug resistance of the first generation and the second generation of ALK inhibitors.

Abstract: The present invention discloses a five-membered heterocyclic amide WNT pathway inhibitor, which belongs to a compound that regulates the activity of a Wnt signaling pathway, and provides a method for preparing such a compound, and the use of such a compound in preparing a medicament that antagonizes the Wnt signaling pathway. The five-membered heterocyclic amide WNT pathway inhibitor provided by the invention has a remarkable anti-tumor activity based on a target-based rational drug design of, and can be used for the development of a new generation of Wnt pathway inhibitors, and has a great clinical application value and considerable market potential.

Abstract: A method for forming a multi-font library can include extracting characters from a plurality of standard font libraries defined in existing international or national coding standards; configuring at least one customized code for each of the extracted characters, the number of customized codes of the each character is equal to the number of fonts of the character and the customized codes correspond to the fonts in a one-to-one manner; and storing the extracted characters and the customized codes thereof to form the multi-font library. An apparatus for forming a multi-font library, and a method and apparatus for displaying different fonts by using the multi-font library are correspondingly provided. The formed multi-font library is capable of storing and displaying characters using different fonts, and consumes less storage capacity as compared with the prior solution of displaying a plurality of fonts by using a plurality of font libraries.

Abstract: The application relates to the field of computer technology and discloses methods, client apparatus, and systems for changing a font for an application program. Methods can include: sending a request for obtaining information on available font resources to a server when it is need to change a font for an application program; presenting the information on the currently available font information resources after receiving the same from the server; determining a font selected by a user; downloading the selected font from the server; and sending the downloaded font to the application program, so that the application program replaces the currently used font with the downloaded font. Therefore, it is possible to change the font for the application program simply and expediently.

Abstract: Disclosed is a method and system for downloading a font file. This can be used when a user cannot download a font file from a file server when the size of the font file exceeds the gateway limit corresponding to the user. The method includes: splitting the font file into a plurality of sub font files each having a size no larger than the gateway transmission limit threshold, and if the size of the font file to be downloaded by a user device is greater than the gateway transmission limit threshold corresponding to the user device, sending all sub font files to the user device.

Abstract: The present invention provides a mobile payment method, device and system for a server and a client. The mobile payment method for a server includes: receiving a payment request message sent by a client; and selecting one piece of payment channel information in a preset payment channel information set and issuing the same to the client. The payment channel information set includes a plurality of pieces of channel information, regions covered by different payment channel information do not overlap completely, and the multiple pieces of payment channel information cover all regions. The server may select different payment channel information provided by a plurality of payment providers to form a payment channel information set so that the payment server that may be provided can cover all regions, which overcomes the limitation in the prior art that a certain piece of payment channel information only covers some regions.