Patents by Inventor Yujun Zhou

Yujun Zhou has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 12119580
    Abstract: The present disclosure relates to an external device-to-external device connector for wireless communication devices, which is configured to electrically connect two spaced external devices together, and comprises two interface members and a coupling member. The inner conductor part and the insulation part of the coupling member are held together by the concave-convex fitting parts opposite to each other, and there is a first gap between the concave-convex fitting part of the inner conductor part and that of the insulation part, which allows the inner conductor part to have radial displacement relative to the insulation part; or, the outer conductor part and the insulating part of the coupling member are held together by the concave-convex fitting parts opposite to each other, and there is a second gap between the concave-convex fitting part of the outer conductor part and that of the insulating part, which allows radial displacement of the insulating part relative to the outer conductor part.
    Type: Grant
    Filed: April 14, 2022
    Date of Patent: October 15, 2024
    Assignee: Outdoor Wireless Networks LLC
    Inventors: Mulan Huang, Yujun Zhang, Yuanyao Zhou
  • Patent number: 11635426
    Abstract: A test strip and kit for testing mycophenolic acid and a preparation method of the test strip are described. The test strip includes a bottom plate and a sample pad, a glassfiber membrane, a nitrocellulose membrane and an absorbent paper which are successively lapped on a surface of the bottom plate, the sample pad is treated by a sample pad treatment fluid; the glassfiber membrane is treated by a glassfiber membrane treatment fluid; the glassfiber membrane is coated by a mycophenolic acid specific-antibody conjugate; the nitrocellulose membrane is provided with a detection line and a quality control line; and a mycophenolic acid protein conjugate is sprayed on the detection line.
    Type: Grant
    Filed: August 30, 2019
    Date of Patent: April 25, 2023
    Assignee: BEIJING DIAGREAT BIOTECHNOLOGIES CO., LTD.
    Inventors: Jianping Zhou, Yujun Zhou, Xiuli Xu
  • Publication number: 20220383987
    Abstract: Provided are a method and device for creating a gene mutation dictionary, and a method and device for compressing genomic data using the gene mutation dictionary. The method for creating a gene mutation dictionary includes: obtaining genome sequence data of a plurality of individuals of a species and reference genome data of the species; aligning genome sequence data of each individual to the reference genome data to obtain a mutation result of the genome sequence data of each individual relative to the reference genome data; partitioning a genome of the species into a plurality of unit regions of biological significance; and generating a plurality of mutant patterns of the individuals in each unit region by statistically analyzing mutant status for each unit region based on the mutation result, and numbering the mutant patterns, to obtain the gene mutation dictionary.
    Type: Application
    Filed: June 29, 2022
    Publication date: December 1, 2022
    Inventors: Chongjun XU, Yujun ZHOU, Ziqing DENG, Meihua GONG, Hui JIANG, Xun XU
  • Publication number: 20210355459
    Abstract: Provided are a Phi29 DNA polymerase mutant with improved thermal stability and an use thereof in sequencing. The phi29 DNA polymerase mutant is represented by A) or B) below: the DNA polymerase mutant represented by the A) is a protein having DNA polymerase activity that is obtained by modifying at least one amino acid residue(s) in the following six sites in a phi29 DNA polymerase amino acid sequence: the 97-th, 123-th, 217-th, 224-th, 515-th, and 474-th sites; the DNA polymerase mutant represented by the B) is a protein having DNA polymerase activity that is derived from the A) by adding a tag sequence to a terminal of the amino acid sequence of the protein represented by the A).
    Type: Application
    Filed: October 11, 2018
    Publication date: November 18, 2021
    Inventors: Zhougang ZHANG, Huanhuan LIU, Yue ZHENG, Yujun ZHOU, Jun XIA, Yuliang DONG, Chongjun XU, Wenwei ZHANG
  • Patent number: 11141732
    Abstract: A detection kit for quickly detecting a lead content lead a sample is provided, and belongs to the technical field of medical in vitro immunoassay. The kit includes a detection card and a quality control; the detection card includes a bottom plate, and a sample pad, a glass fiber membrane, a nitrocellulose membrane and an absorbent paper which are arranged on the surface of the bottom plate sequentially from a loading end. The provided kit has advantages of having simple preprocessing, having no need of digestion, and being economic, fast and convenient, and the like, can realize storage at room temperature, a rapid speed, a high throughout, a low instrument cost, simple and convenient operations, single-person packaging, and detection at any time, which greatly improves the simplicity and convenience of clinical use.
    Type: Grant
    Filed: December 23, 2019
    Date of Patent: October 12, 2021
    Assignee: Beijing Diagreat Biotechnologies Co., Ltd.
    Inventors: Jianping Zhou, Yanxin Wang, Yujun Zhou
  • Patent number: 11104889
    Abstract: Provided are a group of phi29 DNA polymerase mutants having increased thermal stability and use thereof. The phi29 DNA polymerase mutants are proteins obtained by performing point mutation A and/or point mutation B and/or point mutation C on phi29 DNA polymerase, the point mutation A meaning that an amino acid residue M at position 97 of the phi29 DNA polymerase is mutated to other amino acid residue, the point mutation B meaning that an amino acid residue L at position 123 of the phi29 DNA polymerase is mutated into other amino acid residue, and the point mutation C meaning that an amino acid residue E at position 515 of the phi29 DNA polymerase is mutated to other amino acid residue. The stability of the phi29 DNA polymerase mutants is higher than that of a wild-type phi29 DNA polymerase.
    Type: Grant
    Filed: August 9, 2017
    Date of Patent: August 31, 2021
    Assignee: MGI TECH CO., LTD.
    Inventors: Zhougang Zhang, Huanhuan Liu, Yue Zheng, Yujun Zhou, Xing Liu, Yuliang Dong, Chongjun Xu, Wenwei Zhang
  • Publication number: 20210094030
    Abstract: A detection kit for quickly detecting a lead content lead a sample is provided, and belongs to the technical field of medical in vitro immunoassay. The kit includes a detection card and a quality control; the detection card includes a bottom plate, and a sample pad, a glass fiber membrane, a nitrocellulose membrane and an absorbent paper which are arranged on the surface of the bottom plate sequentially from a loading end. The provided kit has advantages of having simple preprocessing, having no need of digestion, and being economic, fast and convenient, and the like, can realize storage at room temperature, a rapid speed, a high throughout, a low instrument cost, simple and convenient operations, single-person packaging, and detection at any time, which greatly improves the simplicity and convenience of clinical use.
    Type: Application
    Filed: December 23, 2019
    Publication date: April 1, 2021
    Applicant: Beijing Diagreat Biotechnologies Co., Ltd.
    Inventors: Jianping Zhou, Yanxin Wang, Yujun Zhou
  • Publication number: 20210096075
    Abstract: The present invention relates to a detection kit for quickly detecting a cadmium content in a sample, and belongs to the technical field of medical in vitro immunoassay. The kit of the present invention includes a detection card and a quality control; the detection card includes a bottom plate, and a sample pad, a glass fiber membrane, a nitrocellulose membrane and an absorbent paper which are arranged on the surface of the bottom plate sequentially from a loading end. The kit of the present invention has advantages of a low detection instrument cost, simple and rapid operations, storage and transportation at room temperature, realization of packaging for a single person, and a good stability.
    Type: Application
    Filed: December 30, 2019
    Publication date: April 1, 2021
    Inventors: Jianping Zhou, Yanxin Wang, Yujun Zhou
  • Patent number: 10961519
    Abstract: Provided are a phi29 DNA polymerase mutant with increased thermo stability, a method for preparing the mutant, the use of the mutant, and a method for increasing the stability of the phi29 DNA polymerase.
    Type: Grant
    Filed: October 18, 2019
    Date of Patent: March 30, 2021
    Assignee: MGI TECH CO., LTD.
    Inventors: Huanhuan Liu, Yue Zheng, Yujun Zhou, Xi Zhang, Zhougang Zhang, Yuliang Dong, Wenwei Zhang, Chongjun Xu, Snezana Drmanac
  • Publication number: 20210055288
    Abstract: The invention provides immunochromatographic test strips for detecting digoxin and uses thereof. The immunochromatographic test strips include a bottom plate, a sample pad, a glass fiber mat, a nitrocellulose membrane and a water absorbing paper that are sequentially overlapped on the bottom plate. The glass fiber mat is sprayed with a digoxin-specific antibody-fluorescent microsphere complex. The nitrocellulose membrane is sequentially provided with a detection line coated with digoxin protein conjugate and a quality control line coated with a secondary antibody. The digoxin-specific antibody-fluorescent microsphere complex is obtained by conjugation between a digoxin monoclonal antibody or a digoxin polyclonal antibody and a fluorescent microsphere. The digoxin protein conjugate includes a digoxin-conjugated rabbit albumin or a digoxin-conjugated rabbit ovalbumin. The test strips provided by the invention are low cost, provide simple and rapid use, and have excellent stability and high sensitivity.
    Type: Application
    Filed: October 10, 2019
    Publication date: February 25, 2021
    Applicant: Beijing Diagreat Biotechnologies Co., Ltd.
    Inventors: Jianping ZHOU, Yujun ZHOU, Xiuli XU
  • Publication number: 20210025880
    Abstract: A test strip and kit for testing mycophenolic acid and a preparation method of the test strip are described. The test strip includes a bottom plate and a sample pad, a glassfiber membrane, a nitrocellulose membrane and an absorbent paper which are successively lapped on a surface of the bottom plate, the sample pad is treated by a sample pad treatment fluid; the glassfiber membrane is treated by a glassfiber membrane treatment fluid; the glassfiber membrane is coated by a mycophenolic acid specific-antibody conjugate; the nitrocellulose membrane is provided with a detection line and a quality control line; and a mycophenolic acid protein conjugate is sprayed on the detection line.
    Type: Application
    Filed: August 30, 2019
    Publication date: January 28, 2021
    Applicant: BEIJING DIAGREAT BIOTECHNOLOGIES CO., LTD.
    Inventors: Jianping ZHOU, Yujun ZHOU, Xiuli XU
  • Publication number: 20200208126
    Abstract: Provided are a group of phi29 DNA polymerase mutants having increased thermal stability and use thereof. The phi29 DNA polymerase mutants are proteins obtained by performing point mutation A and/or point mutation B and/or point mutation C on phi29 DNA polymerase, the point mutation A meaning that an amino acid residue M at position 97 of the phi29 DNA polymerase is mutated to other amino acid residue, the point mutation B meaning that an amino acid residue L at position 123 of the phi29 DNA polymerase is mutated into other amino acid residue, and the point mutation C meaning that an amino acid residue E at position 515 of the phi29 DNA polymerase is mutated to other amino acid residue. The stability of the phi29 DNA polymerase mutants is higher than that of a wild-type phi29 DNA polymerase.
    Type: Application
    Filed: August 9, 2017
    Publication date: July 2, 2020
    Inventors: Zhougang Zhang, Huanhuan Liu, Yue Zheng, Yujun Zhou, Xing Liu, Yuliang Dong, Chongjun Xu, Wenwei Zhang
  • Publication number: 20200115686
    Abstract: Provided are a phi29 DNA polymerase mutant with increased thermo stability, a method for preparing the mutant, the use of the mutant, and a method for increasing the stability of the phi29 DNA polymerase.
    Type: Application
    Filed: October 18, 2019
    Publication date: April 16, 2020
    Inventors: Huanhuan Liu, Yue Zheng, Yujun Zhou, Xi Zhang, Zhougang Zhang, Yuliang Dong, Wenwei Zhang, Chongjun Xu, Snezana Drmanac