Patents by Inventor Yuk-Ching TSE-DINH

Yuk-Ching TSE-DINH has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Treatments of prostate cancer
    Patent number: 11839621
    Abstract: The present invention provides compounds, compositions, and methods for the treatment of prostate cancers, preferably, advanced prostate cancers. The subject invention also provides compounds, compositions, and methods for preventing/slowing down/reducing the progress and proliferation of prostate cancer cells. The subject invention further provides compounds, compositions, and methods for inhibiting DNA repair within cancer cells to slow tumor growth, preferably, by inhibiting BER capacity, including pol ? and LIG I.
    Type: Grant
    Filed: October 21, 2022
    Date of Patent: December 12, 2023
    Assignee: THE FLORIDA INTERNATIONAL UNIVERSITY BOARD OF TRUSTEES
    Inventors: Yuk-Ching Tse-Dinh, Yuan Liu, Irina Agoulnik
  • TREATMENTS OF PROSTATE CANCER
    Publication number: 20230226090
    Abstract: The present invention provides compounds, compositions, and methods for the treatment of prostate cancers, preferably, advanced prostate cancers. The subject invention also provides compounds, compositions, and methods for preventing/slowing down/reducing the progress and proliferation of prostate cancer cells. The subject invention further provides compounds, compositions, and methods for inhibiting DNA repair within cancer cells to slow tumor growth, preferably, by inhibiting BER capacity, including pol ? and LIG I.
    Type: Application
    Filed: October 21, 2022
    Publication date: July 20, 2023
    Applicant: THE FLORIDA INTERNATIONAL UNIVERSITY BOARD OF TRUSTEES
    Inventors: YUK-CHING TSE-DINH, YUAN LIU, IRINA AGOULNIK
  • Treatments of prostate cancer
    Patent number: 11478496
    Abstract: The present invention provides compounds, compositions and methods for the treatment of prostate cancers, preferably, advanced prostate cancers. The subject invention also provides compounds, compositions and methods for preventing/slowing down/reducing the progress and proliferation of prostate cancer cells. The subject invention further provides compounds, compositions and methods for inhibiting DNA repair within cancer cells to slow tumor growth, preferably, by inhibiting BER capacity, including pol ? and LIG I.
    Type: Grant
    Filed: March 17, 2022
    Date of Patent: October 25, 2022
    Assignee: THE FLORIDA INTERNATIONAL UNIVERSITY BOARD OF TRUSTEES
    Inventors: Yuk-Ching Tse-Dinh, Yuan Liu, Irina Agoulnik
  • TREATMENTS OF PROSTATE CANCER
    Publication number: 20220211736
    Abstract: The present invention provides compounds, compositions and methods for the treatment of prostate cancers, preferably, advanced prostate cancers. The subject invention also provides compounds, compositions and methods for preventing/slowing down/reducing the progress and proliferation of prostate cancer cells. The subject invention further provides compounds, compositions and methods for inhibiting DNA repair within cancer cells to slow tumor growth, preferably, by inhibiting BER capacity, including pol ? and LIG I.
    Type: Application
    Filed: March 17, 2022
    Publication date: July 7, 2022
    Applicant: THE FLORIDA INTERNATIONAL UNIVERSITY BOARD OF TRUSTEES
    Inventors: YUK-CHING TSE-DINH, YUAN LIU, IRINA AGOULNIK
  • Treatments of prostate cancer
    Patent number: 11304969
    Abstract: The present invention provides compounds, compositions and methods for the treatment of prostate cancers, preferably, advanced prostate cancers. The subject invention also provides compounds, compositions and methods for preventing/slowing down/reducing the progress and proliferation of prostate cancer cells. The subject invention further provides compounds, compositions and methods for inhibiting DNA repair within cancer cells to slow tumor growth, preferably, by inhibiting BER capacity, including pol ? and LIG I.
    Type: Grant
    Filed: January 24, 2020
    Date of Patent: April 19, 2022
    Assignee: THE FLORIDA INTERNATIONAL UNIVERISTY BOARD OF TRUSTEES
    Inventors: Yuk-Ching Tse-Dinh, Yuan Liu, Irina Agoulnik
  • TREATMENTS OF PROSTATE CANCER
    Publication number: 20210228609
    Abstract: The present invention provides compounds, compositions and methods for the treatment of prostate cancers, preferably, advanced prostate cancers. The subject invention also provides compounds, compositions and methods for preventing/slowing down/reducing the progress and proliferation of prostate cancer cells. The subject invention further provides compounds, compositions and methods for inhibiting DNA repair within cancer cells to slow tumor growth, preferably, by inhibiting BER capacity, including pol ? and LIG I.
    Type: Application
    Filed: January 24, 2020
    Publication date: July 29, 2021
    Applicant: THE FLORIDA INTERNATIONAL UNIVERSITY BOARD OF TRUSTEES
    Inventors: YUK-CHING TSE-DINH, YUAN LIU, IRINA AGOULNIK
  • Bacterial topoisomerase I inhibitors with antibacterial activity
    Patent number: 10654869
    Abstract: The present invention provides compounds as bacterial topoisomerase inhibitors with antibacterial activity. The present invention also provides pharmaceutical compositions comprising at least one of the compounds and methods of using the compounds and pharmaceutical compositions as antibacterial agents for treating infectious diseases.
    Type: Grant
    Filed: March 4, 2019
    Date of Patent: May 19, 2020
    Assignees: THE FLORIDA INTERNATIONAL UNIVERSITY BOARD OF TRUSTEES, UNIVERSITY OF HAWAII
    Inventors: Yuk-Ching Tse-Dinh, Dianqing Sun
  • BACTERIAL TOPOISOMERASE I INHIBITORS WITH ANTIBACTERIAL ACTIVITY
    Publication number: 20190194224
    Abstract: The present invention provides compounds as bacterial topoisomerase inhibitors with antibacterial activity.
    Type: Application
    Filed: March 4, 2019
    Publication date: June 27, 2019
    Inventors: Yuk-Ching TSE-DINH, Dianqing SUN
  • Bacterial topoisomerase I inhibitors with antibacterial activity
    Patent number: 10266550
    Abstract: The present invention provides compounds as bacterial topoisomerase inhibitors with antibacterial activity. The present invention also provides pharmaceutical compositions comprising at least one of the compounds and methods of using the compounds and pharmaceutical compositions as antibacterial agents for treating infectious diseases.
    Type: Grant
    Filed: September 18, 2017
    Date of Patent: April 23, 2019
    Assignees: THE FLORIDA INTERNATIONAL UNIVERSITY BOARD OF TRUSTEES, UNIVERSITY OF HAWAII
    Inventors: Yuk-Ching Tse-Dinh, Dianqing Sun
  • Bacterial topoisomerase inhibitors and use thereof
    Patent number: 9988341
    Abstract: The present invention provides novel compounds as bacterial topoisomerase inhibitors with antibacterial activity. The present invention also provides pharmaceutical compositions comprising at least one of the compounds and methods of using the compounds and pharmaceutical compositions as antibacterial agents for treating infectious diseases.
    Type: Grant
    Filed: April 19, 2017
    Date of Patent: June 5, 2018
    Assignees: THE FLORIDA INTERNATIONAL UNIVERSITY BOARD OF TRUSTEES, TORREY PINES INSTITUTE FOR MOLECULAR STUDIES
    Inventors: Yuk-Ching Tse-Dinh, Marcello Angelo Giulianotti, Richard Allen Houghten
  • BACTERIAL TOPOISOMERASE I INHIBITORS WITH ANTIBACTERIAL ACTIVITY
    Publication number: 20180079757
    Abstract: The present invention provides compounds as bacterial topoisomerase inhibitors with antibacterial activity. The present invention also provides pharmaceutical compositions comprising at least one of the compounds and methods of using the compounds and pharmaceutical compositions as antibacterial agents for treating infectious diseases.
    Type: Application
    Filed: September 18, 2017
    Publication date: March 22, 2018
    Inventors: Yuk-Ching TSE-DINH, Dianqing SUN
  • BACTERIAL TOPOISOMERASE INHIBITORS AND USE THEREOF
    Publication number: 20170298004
    Abstract: The present invention provides novel compounds as bacterial topoisomerase inhibitors with antibacterial activity. The present invention also provides pharmaceutical compositions comprising at least one of the compounds and methods of using the compounds and pharmaceutical compositions as antibacterial agents for treating infectious diseases.
    Type: Application
    Filed: April 19, 2017
    Publication date: October 19, 2017
    Applicant: The Florida International University Board of Trustees
    Inventors: Yuk-Ching TSE-DINH, Marcello Angelo GIULIANOTTI, Richard Allen HOUGHTEN