Patents by Inventor Yuka Ikenoue

Yuka Ikenoue has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method of treating inflammatory bowel disease
    Patent number: 8309576
    Abstract: The present invention provides a method of improving or treating inflammatory bowel disease through suppression of the expression of inflammatory cytokines based on the action mechanism of suppression of NF-?B activation by administering feruloyl serotonin to a subject in need of treatment of inflammatory bowel disease. The feruloyl serotonin of the present invention can be administered as a pharmaceutical agent or a food.
    Type: Grant
    Filed: November 10, 2008
    Date of Patent: November 13, 2012
    Assignee: Ajinomoto Co., Inc.
    Inventors: Yuji Naito, Naoto Koyama, Katsuya Suzuki, Hideaki Kihara, Yuka Ikenoue
  • Heterocyclic compounds
    Patent number: 7902179
    Abstract: A pharmaceutical composition containing a heterocyclic compound of the formula (I) wherein each symbol is as defined in the specification, an isomer thereof, a solvate thereof or a pharmaceutically acceptable salt thereof as an active ingredient has a superior TNF-? production suppressing action. Accordingly, it is useful for the prophylaxis or treatment of various diseases caused by abnormal production of TNF-?.
    Type: Grant
    Filed: April 26, 2002
    Date of Patent: March 8, 2011
    Assignee: Ajinomoto Co., Inc.
    Inventors: Yasuhiro Tanaka, Kohichi Fujita, Yoshitomo Chujoh, Syunsuke Fukuda, Yuka Ikenoue, Tomoyuki Tagami, Akira Chiba, Ariko Kodaira, Hideki Matsumoto, Tadakiyo Nakagawa, Tatsuhiro Yamada, Manabu Suzuki, Masahiro Murata
  • ANTI-INFLAMMATORY COMPOSITION
    Publication number: 20090156657
    Abstract: The present invention provides a method of improving or preventing various conditions through suppression of the expression of inflammatory cytokines based on the action mechanism of suppression of NF-?B activation. The present invention provides a composition for suppressing NF-?B activation, containing a serotonin derivative such as feruloyl serotonin (N-feruloyl serotonin) and p-coumaroyl serotonin (N-(p-coumaroyl)serotonin), a composition for suppressing the expression of VCAM-1 and/or MCP-1 via NF-?B, containing the serotonin derivative and an anti-inflammatory composition containing the serotonin derivative. The composition of the present invention can be used as a pharmaceutical agent or a food.
    Type: Application
    Filed: November 10, 2008
    Publication date: June 18, 2009
    Applicant: Ajinomoto Co., Inc.
    Inventors: Yuji Naito, Naoto Koyama, Katsuya Suzuki, Hideaki Kihara, Yuka Ikenoue
  • Heterocyclic compounds
    Patent number: 7279484
    Abstract: The inventive subject matter relates to compounds, pharmaceutical compositions, and kits containing a heterocyclic compound represented by the formula (I) wherein R is an alkyl group optionally having substituent(s) etc., X is an amino group optionally having substituent(s), Y1 and Y2 are nitrogen atoms etc., an isomer or solvate thereof or a pharmaceutically acceptable salt thereof as an active ingredient.
    Type: Grant
    Filed: April 28, 2005
    Date of Patent: October 9, 2007
    Assignee: Ajinomoto Co., Inc.
    Inventors: Tatsuhiro Yamada, Tadakiyo Nakagawa, Yasuhiro Tanaka, Kohichi Fujita, Tomoyuki Tagami, Yuka Ikenoue, Shunsuke Fukuda, Yoshitomo Chujo, Manabu Suzuki, Masahiro Murata
  • Heterocyclic compounds
    Publication number: 20050250796
    Abstract: The inventive subject matter relates to compounds, pharmaceutical compositions, and kits containing a heterocyclic compound represented by the formula (I) wherein R is an alkyl group optionally having substituent(s) etc., X is an amino group optionally having substituent(s), Y1 and Y2 are nitrogen atoms etc., an isomer or solvate thereof or a pharmaceutically acceptable salt thereof as an active ingredient.
    Type: Application
    Filed: April 28, 2005
    Publication date: November 10, 2005
    Inventors: Tatsuhiro Yamada, Tadakiyo Nakagawa, Yasuhiro Tanaka, Kohichi Fujita, Tomoyuki Tagami, Yuka Ikenoue, Shunsuke Fukuda, Yoshitomo Chujo, Manabu Suzuki, Masahiro Murata
  • Heterocyclic compounds
    Publication number: 20040147546
    Abstract: A pharmaceutical composition containing a heterocyclic compound of the formula (I) 1
    Type: Application
    Filed: February 24, 2004
    Publication date: July 29, 2004
    Inventors: Yasuhiro Tanaka, Kohichi Fujita, Yoshitomo Chujoh, Syunsuke Fukuda, Yuka Ikenoue, Tomoyuki Tagami, Akira Chiba, Ariko Kodaira, Hideki Matsumoto, Tadakiyo Nakagawa, Tatsuhiro Yamada, Manabu Suzuki, Masahiro Murata
  • Group of antitumor compounds and method for producing the same
    Patent number: 5843755
    Abstract: A mold belonging to the genus Ascochyta is cultivated with a medium to obtain a culture. A compound having a structure represented by the following formula and having an antitumor activity, which is capable of forming a tautomeric equilibrium mixture composed of tautomers, is collected from the culture, or a mixture of the tautomers is collected from the culture.
    Type: Grant
    Filed: June 10, 1997
    Date of Patent: December 1, 1998
    Assignee: Ajinomoto Co., Inc.
    Inventors: Yoko Obayashi, Toshihiko Yoshimura, Yuka Ikenoue, Ryosuke Fudo, Masahiro Murata, Toshihiko Ando