Patents by Inventor Yuka Kanayama

Yuka Kanayama has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • .gamma.-chain humaninterleukin-2 receptor polypeptide and method of making
    Patent number: 5856140
    Abstract: A polypeptide which specifically binds to the .gamma.-chain of the human interleukin-2 receptor and selectively inhibits the binding of the .gamma.-chain of human interleukin-2 receptor to the .beta.-chain of the same is provided. The polypeptide has an activity of blocking the human interleukin-2 response. Also provided are an immunosuppressant containing the polypeptide, a DNA gene coding for the polypeptide, a recombinant DNA having the gene, a transformant having the recombinant DNA, and a method for producing the intended polypeptide by incubating the transformant. The novel polypeptide can be used independently, or with substances capable of inhibiting the binding of interleukin-2 to the interleukin-2 receptor, as a medicine for preventing the rejection of grafts after transplantation and also for curing inflammatory diseases such as allergic diseases and autoimmune diseases.
    Type: Grant
    Filed: April 24, 1996
    Date of Patent: January 5, 1999
    Assignees: Ajinomoto Co., Inc., Kazuo Sugamura
    Inventors: Toshiro Shimamura, Junji Hamuro, Harumi Nakazawa, Yuka Kanayama, Kazuo Sugamura, Toshikazu Takeshita
  • Monoclonal antibodies which bind the gamma chain of human interleukin-2 receptor
    Patent number: 5582826
    Abstract: A polypeptide which specifically binds to the .gamma.-chain of the human interleukin-2 receptor and selectively inhibits the binding of the .gamma.-chain of human interleukin-2 receptor to the .beta.-chain of the same is provided. The polypeptide has an activity of blocking the human interleukin-2 response. Also provided are an immunosuppressant containing the polypeptide, a DNA gene coding for the polypeptide, a recombinant DNA having the gene, a transformant having the recombinant DNA, and a method for producing the intended polypeptide by incubating the transformant. The novel polypeptide can be used independently, or with substances capable of inhibiting the binding of interleukin-2 to the interleukin-2 receptor, as a medicine for preventing the rejection of grafts after transplantation and also for curing inflammatory diseases such as allergic diseases and autoimmune diseases.
    Type: Grant
    Filed: April 21, 1994
    Date of Patent: December 10, 1996
    Assignees: Ajinomoto Co., Inc., Kazuo Sugamura
    Inventors: Toshiro Shimamura, Junji Hamuro, Harumi Nakazawa, Yuka Kanayama, Kazuo Sugamura, Toshikazu Takeshita