Abstract: A window regulator includes a carrier plate holding a windowpane, a drum rotated by driving a motor that generates a driving force, a wire whose one end is connected to the carrier plate and whose other end is connected to the drum, a wire end fixed to an end on a side of the one end of the wire, and a housing member that is formed of a synthetic resin and houses the wire end. The housing member is configured to define a housing hole that is surrounded by a base in which an inserting hole to insert the wire is formed, and a sidewall that is formed extending from an outer edge of the base. The wire end is housed in the housing hole while being pressed against a protrusion that protrudes from the sidewall.

Abstract: [Problem] To provide a compound which is useful as an agent for preventing and/or treating kidney diseases. [Means for Solution] The present inventors have studied compounds having a trypsin inhibitory activity, and have confirmed that a guanidinobenzoic acid ester compound has a trypsin inhibitory activity, thereby completing the present invention. The guanidinobenzoic acid ester compound of the present invention can be used as an agent for preventing and/or treating kidney diseases (for example, chronic kidney disease, acute glomerulonephritis, acute kidney injury, and the like) as an agent which will substitute low-protein diet therapy, and/or as an agent for preventing and/or treating trypsin-related diseases (for example, chronic pancreatitis, gastroesophageal reflux disease, hepatic encephalopathy, influenza, and the like).

Abstract: A window regulator includes a carrier plate holding a windowpane, a drum rotated by driving a motor that generates a driving force, a wire whose one end is connected to the carrier plate and whose other end is connected to the drum, a wire end fixed to an end on a side of the one end of the wire, and a housing member that is formed of a synthetic resin and houses the wire end. The housing member is configured to define a housing hole that is surrounded by a base in which an inserting hole to insert the wire is formed, and a sidewall that is formed extending from an outer edge of the base. The wire end is housed in the housing hole while being pressed against a protrusion that protrudes from the sidewall.

Abstract: The present invention provides a sirtuin activator with an active component composed of black ginger or a black ginger extract, which is easily obtainable, extremely safe, and eaten from old. The present invention further provides a sirtuin activator with an active component of polyalkoxyflavonoid compound represented by general formula (I) and having a sirtuin activation effect that is 10 folds that of resveratrol or higher: wherein, R1 to R7 are each independently a hydrogen atom, a hydroxyl group, or a C1 to C6 lower alkoxy group.

Abstract: [Problem]To provide a compound which is useful as an agent for preventing and/or treating kidney diseases. [Means for Solution]The present inventors have studied compounds having a trypsin inhibitory activity, and have confirmed that a guanidinobenzoic acid ester compound has a trypsin inhibitory activity, thereby completing the present invention. The guanidinobenzoic acid ester compound of the present invention can be used as an agent for preventing and/or treating kidney diseases (for example, chronic kidney disease, acute glomerulonephritis, acute kidney injury, and the like) as an agent which will substitute low-protein diet therapy, and/or as an agent for preventing and/or treating trypsin-related diseases (for example, chronic pancreatitis, gastroesophageal reflux disease, hepatic encephalopathy, influenza, and the like).

Abstract: The present invention provides a sirtuin activator with an active component composed of black ginger or a black ginger extract, which is easily obtainable, extremely safe, and eaten from old. The present invention further provides a sirtuin activator with an active component of polyalkoxyflavonoid compound represented by general formula (I) and having a sirtuin activation effect that is 10 folds that of resveratrol or higher: wherein, R1 to R7 are each independently a hydrogen atom, a hydroxyl group, or a C1 to C6 lower alkoxy group.