Abstract: Disclosed is a method for evaluating cell differentiation state, including inducing pluripotent stem cells to differentiate into mesodermal cells in a liquid medium by a first differentiation treatment for inducing pluripotent stem cells to differentiate into mesodermal cells and a second differentiation treatment for inducing the mesodermal cells to differentiate into cardiomyocytes; collecting a supernatant of the liquid medium comprising cells induced to differentiate by the second differentiation treatment; and measuring miRNA-3p in miR-1/133a cluster in the supernatant, where the miRNA-3p is at least one selected from a group consisting of miR-1-3p and miR-133a-3p, and the measured value of miRNA-3p is an index of differentiation into cardiomyocytes.

Abstract: According to an aspect, there is provided a snug-fit garment covering at least a portion of a wearer's body and methods of making same. The garment includes a double-layered sleeve having a width and length. The double-layered sleeve including an inner sleeve layer and an outer sleeve layer. The outer sleeve layer at least partially overlaps with the inner sleeve layer. At least one of the outer sleeve layer and the inner sleeve layer is compressive. A space is defined between the inner and outer sleeve layers. The garment also includes one or more permanent or detachable attachments between the inner and outer sleeve layers for securing the outer sleeve layer over the inner sleeve layer thereby preserving the space between the inner and outer sleeve layers. The space includes at least one pocket for storing an object.

Abstract: The present invention provides a pocket structure for lower body garments that minimizes the risk of the contents accidentally spilling out of a garment's pockets when the wearer of the garment places their body into a position other than a standing position. The pocket structure can be incorporated into a variety of garments designed to be worn on the lower body, including, but not limited to, pants, shorts, skirts, skorts, dresses, jumpsuits, one-piece outfits, snow pants, rain pants, swim trunks, running tights, and others. The pocket structure can be incorporated into garments designed for athletic activities, garments designed for a business casual environment, as well as designed and configured for on-the-move (OTM) usage. The pocket structure is configured to prevent spillage of contents over a wide range of the garment wearer's body positions.

Abstract: A vortex generator might be attached to various types of articles to reduce the drag. For example, vortex generators might be attached to a garment or to adhesive tape. In addition, vortex generators might be attached to various types of athletic equipment. A mapping can suggest placement of a vortex-generator arrangement on an article, as well as prescribe particular vortex-generator arrangements for regions of a person.

Abstract: A cord-lock assembly for slidably adjusting a length of cord is provided. The assembly may include various components such as a cord, a cord lock, and an article layer into which the cord lock and cord may be at least partially integrated. The cord lock may include one or more components that releasably clamp onto the cord and engage the cord through resistance provided by a biasing element. The cord-lock assembly may be configured such that a force applied to the cord lock in axial alignment with an aperture in which the cord lock is positioned allows adjustment of a length of cord extending through the cord lock and/or through the aperture layer.

Abstract: The present invention provides an image analysis method for generating data indicating a region of a cell nucleus in an image of a tissue or a cell. The image analysis method is a method for analyzing an image of a tissue or a cell using a deep learning algorithm of a neural network structure, and generates data indicating a region of a cell nucleus in an analysis target image by the deep learning algorithm by generating analysis data from the analysis target image including an analysis target tissue or cell, and inputting the analysis data in the deep learning algorithm.

Abstract: The present invention provides an image analysis method for generating data indicating a region of a cell nucleus in an image of a tissue or a cell. The image analysis method is a method for analyzing an image of a tissue or a cell using a deep learning algorithm of a neural network structure, and generates data indicating a region of a cell nucleus in an analysis target image by the deep learning algorithm by generating analysis data from the analysis target image including an analysis target tissue or cell, and inputting the analysis data in the deep learning algorithm.

Abstract: A dynamic vent-slit structure for a lower body article of apparel is provided. The article includes a pelvic portion for covering a pelvic area of a wearer when the article is in an as-worn position, and a plurality of slits in a repeating fashion, wherein a spacing between two adjacent slits in linear alignment is less than a length of a slit in non-linear alignment with the two slits and that is offset from the two slits such that the slit in non-linear alignment overlies the spacing between the slits in linear alignment, and the slit in non-linear alignment is parallel to the slits in linear alignment. The slits may be positioned in one or more groupings or aligned in different directions to open in response to different directions of stretch or movement, to provide dynamic or motion activated venting in the article.

Abstract: Disclosed is a method for concentrating extracellular vesicles, comprising preparing a mixture comprising a first fraction and a second fraction by mixing a liquid sample comprising extracellular vesicles, a polysaccharide, and a polyether having an average molecular weight of 20,000 or less, wherein the first fraction comprises a higher concentration of extracellular vesicles than the second fraction, and the first fraction comprises a higher concentration of extracellular vesicles than the liquid sample.

Abstract: An image analysis method for generating data indicating a tumorigenic state of an image of a tissue or a cell. The image analysis method is an image analysis method for analyzing an image of a tissue or a cell using a deep learning algorithm of a neural network structure, analysis data are generated from the analysis target image including a tissue or cell to be analyzed, the analysis data are input to the deep learning algorithm, and data indicating the tumorigenic state of tissues or cells in the analysis target image are generated by the depth learning algorithm.

Abstract: A cord-lock assembly for slidably adjusting a length of cord is provided. The assembly may include various components such as a cord, a cord lock, and an article layer into which the cord lock and cord may be at least partially integrated. The cord lock may include one or more components that releasably clamp onto the cord and engage the cord through resistance provided by a biasing element. The cord-lock assembly may be configured such that a force applied to the cord lock in axial alignment with an aperture in which the cord lock is positioned allows adjustment of a length of cord extending through the cord lock and/or through the aperture layer.

Abstract: An image analysis method for analyzing an image of a tissue collected from a subject using a deep learning algorithm of a neural network structure. The image analysis method includes generating analysis data from the analysis target image that includes the tissue to be analyzed, inputting the analysis data to a deep learning algorithm, and generating data indicating a layer structure configuring a tissue in the analysis target image by the deep learning algorithm.

Abstract: A cord-lock assembly for slidably adjusting a length of cord is provided. The assembly may include various components such as a cord, a cord lock, and an article layer into which the cord lock and cord may be at least partially integrated. The cord lock may include one or more components that releasably clamp onto the cord and engage the cord through resistance provided by a biasing element. The cord-lock assembly may be configured such that a force applied to the cord lock in axial alignment with an aperture in which the cord lock is positioned allows adjustment of a length of cord extending through the cord lock and/or through the aperture layer.

Abstract: The present invention provides an image analysis method for generating data indicating a region of a cell nucleus in an image of a tissue or a cell. The image analysis method is a method for analyzing an image of a tissue or a cell using a deep learning algorithm of a neural network structure, and generates data indicating a region of a cell nucleus in an analysis target image by the deep learning algorithm by generating analysis data from the analysis target image including an analysis target tissue or cell, and inputting the analysis data in the deep learning algorithm.

Abstract: The present invention provides an image analysis method for generating data indicating a region of a cell nucleus in an image of a tissue or a cell. The image analysis method is a method for analyzing an image of a tissue or a cell using a deep learning algorithm of a neural network structure, and generates data indicating a region of a cell nucleus in an analysis target image by the deep learning algorithm by generating analysis data from the analysis target image including an analysis target tissue or cell, and inputting the analysis data in the deep learning algorithm.

Abstract: An article that includes a vortex-generator device may include various features. For example, the article may include a material layer and one or more elongate members coupled to the material layer. In addition, the one or more elongate members interconnect two or more vortex generators.

Abstract: A cord lock includes various components used to slidably adjust a cord length, such as one or more housing components that releasably clamp around the cord. In one aspect, the cord lock includes an arrangement of magnets that bias the cord-lock housing components away from one another, in order to secure the cord between the housing components. The housing components can be pressed towards one another to slidably adjust the cord. In a further aspect, the cord lock may also include a magnetized excess-cord retainer that attaches to a portion of the cord and that releasably attaches to the cord lock in order to help gather excess cord pulled through the cord lock.

Abstract: Decals with dimensional offsets are disclosed. The decals may be part of a decal kit or may be applied to an article. The decals include an overlay having multiple dimensional spacers. When applied to an article, the decal overlay bonds to the article, securing the dimensional spacers between the overlay and the article creating dimensional offsets. The dimensional offsets are positioned on an interior surface of the article so that contact with a wearer's skin is minimized, reducing the perception of cling.

Abstract: A cord lock includes various components used to slidably adjust a cord length, such as one or more housing components that releasably clamp around the cord. In one aspect, the cord lock includes an arrangement of magnets that bias the cord-lock housing components away from one another, in order to secure the cord between the housing components. The housing components can be pressed towards one another to slidably adjust the cord. In a further aspect, the cord lock may also include a magnetized excess-cord retainer that attaches to a portion of the cord and that releasably attaches to the cord lock in order to help gather excess cord pulled through the cord lock.

Abstract: A problem to be addressed is to provide a method that can evaluate the state of undifferentiated cells without destroying cells. The above problem is solved by providing a method for evaluating the state of undifferentiated cells. The method includes: measuring at least one miRNA selected from miR371, miR372, and miR373 in a liquid phase fraction of a liquid that contains undifferentiated cells; and evaluating a state of the undifferentiated cells on the basis of a measurement value of the miRNA.