Patents by Inventor Yuki Kawano

Yuki Kawano has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10973762
    Abstract: Provided is a polymeric micelle type DDS preparation that may efficiently exhibit pharmacological activity effects by enhancing migration characteristics, penetrability, and retention characteristics toward a diseased target tissue such as a tumor tissue or an inflammation-affected tissue, and thereby enhancing the action of a pharmacologically active substance. Disclosed is a block copolymer (A) having a hydrophilic polymer segment linked to a hydrophobic polymer segment, the hydrophilic polymer segment containing a polyethylene glycol chain, and the hydrophobic polymer segment containing a polyamino acid chain having a hydrophobic substituent in a side chain, wherein the hydrophilic polymer segment has a target binding site bonded thereto, and the main chain polymer combining the polyethylene glycol chain and the polyamino acid chain has a molecular weight of not less than 2 kilodaltons and not more than 10 kilodaltons.
    Type: Grant
    Filed: July 25, 2017
    Date of Patent: April 13, 2021
    Assignee: Nippon Kayaku Kabushiki Kaisha
    Inventors: Dai Kurihara, Tsuyoshi Fukuda, Yuki Kawano, Keiichirou Yamamoto
  • Patent number: 10869937
    Abstract: Provided are a block copolymer having an enhanced effect of imaging the interior of a tumor compared to known block copolymers and imaging probes using the known block copolymers; and an imaging probe using the block copolymer.
    Type: Grant
    Filed: July 21, 2017
    Date of Patent: December 22, 2020
    Assignee: Nippon Kayaku Kabushiki Kaisha
    Inventors: Keiichirou Yamamoto, Yuki Kawano
  • Patent number: 10814016
    Abstract: Provided are a block copolymer having an enhanced effect of imaging the interior of a tumor compared to known block copolymers and imaging probes using the known block copolymers; and an imaging probe using the block copolymer.
    Type: Grant
    Filed: July 21, 2017
    Date of Patent: October 27, 2020
    Assignee: Nippon Kayaku Kabushiki Kaisha
    Inventors: Keiichirou Yamamoto, Yuki Kawano
  • Publication number: 20190307905
    Abstract: Provided are a block copolymer having an enhanced effect of imaging the interior of a tumor compared to known block copolymers and imaging probes using the known block copolymers; and an imaging probe using the block copolymer.
    Type: Application
    Filed: July 21, 2017
    Publication date: October 10, 2019
    Inventors: Keiichirou Yamamoto, Yuki Kawano
  • Publication number: 20190262269
    Abstract: Provided is a polymeric micelle type DDS preparation that may efficiently exhibit pharmacological activity effects by enhancing migration characteristics, penetrability, and retention characteristics toward a diseased target tissue such as a tumor tissue or an inflammation-affected tissue, and thereby enhancing the action of a pharmacologically active substance. Disclosed is a block copolymer (A) having a hydrophilic polymer segment linked to a hydrophobic polymer segment, the hydrophilic polymer segment containing a polyethylene glycol chain, and the hydrophobic polymer segment containing a polyamino acid chain having a hydrophobic substituent in a side chain, wherein the hydrophilic polymer segment has a target binding site bonded thereto, and the main chain polymer combining the polyethylene glycol chain and the polyamino acid chain has a molecular weight of not less than 2 kilodaltons and not more than 10 kilodaltons.
    Type: Application
    Filed: July 25, 2017
    Publication date: August 29, 2019
    Inventors: Dai Kurihara, Tsuyoshi Fukuda, Yuki Kawano, Keiichirou Yamamoto
  • Patent number: 6289687
    Abstract: An integral type air conditioner is provided having its main unit fastened to an outer case by fastening device at a position manageable inside the room, instead of by fastening the main unit to the outer case with screws inserted from the outside of the outer case through the side faces thereof. Regardless of conditions of installation, the main unit can easily and surely be fastened and the main unit is never pushed out from the outside to the inside of the main unit. The integral type air conditioner has the outer case attached to an opening of a wall and the main unit is slid into the outer case and installed therein. The fastening device is provided for securely coupling the main unit and the outer case to each other at a position manageable inside the room so as to prevent the main unit from being pushed out into the room.
    Type: Grant
    Filed: May 5, 2000
    Date of Patent: September 18, 2001
    Assignee: Sharp Kabushiki Kaisha
    Inventors: Yuki Kawano, Yuji Shimamura
  • Publication number: 20010003287
    Abstract: An on-off device disposed at each of the inlet and the outlet of a fluid controller is one of five kinds of on-off devices, i.e., on-off device having a two-port valve, on-off device having a two-port valve and a three-port valve, on-off device having a two-port valve and two three-port valves, on-off device having two three-port valves, and on-off device having three three-port valves. The main bodies of two-port valves of all types of on-off devices are identical in configuration and each have an inlet and an outlet in a bottom face thereof. Main bodies of three-port valves of all types of on-off devices are identical in configuration and each formed in a bottom face thereof with an inlet, an outlet always in communication with the inlet, and an inlet-outlet subopening.
    Type: Application
    Filed: February 13, 1998
    Publication date: June 14, 2001
    Applicant: Armstrong, Westerman, Hattori, McLeland & Naughton
    Inventors: TADAHIRO OHMI, HIROSHI MOROKOSHI, MICHIO YAMAJI, SHIGEAKI TANAKA, KEIJI HIRAO, YUKI KAWANO, TAKASHI HIROSE, KOSUKE YOKOYAMA, MICHIO KURAMOCHI, MASAYUKI HATANO, NOBUKAZU IKEDA
  • Patent number: 6009716
    Abstract: An integral type air conditioner includes an interior heat exchanger, an interior blower, an exterior heat exchanger, an exterior blower, an interior motor, and an exterior motor. In addition, a partition member separates the interior heat exchanger and the interior blower at the interior side from the exterior heat exchanger, the exterior blower, the interior motor and the exterior motor at the exterior side.
    Type: Grant
    Filed: November 17, 1997
    Date of Patent: January 4, 2000
    Assignee: Sharp Kabushiki Kaisha
    Inventors: Yoshiyuki Aoto, Kazuya Yoshikawa, Yuki Kawano, Tomiji Ikarashi, Toshiya Ueno