Abstract: An optimization device includes a determination unit which determines weights for a plurality of constraint conditions imposed on a combinatorial optimization problem, respectively, and a generation unit which generates an energy function for the combinatorial optimization problem using a constant that is a sum of a constant used in formulation of an energy to be optimized in the combinatorial optimization problem and a sum over the plurality of constraint conditions of a constant used in formulation of an energy of one constraint condition multiplied by a weight determined for the one constraint condition.

Abstract: The annealing execution means 73 executes annealing using an energy function, when a solution to a combinatorial optimization problem, and the energy function of a model representing states of individual spins by a first value or a second value which is used to obtain the solution are given, and derives multiple new solutions to the combinatorial optimization problem. The solution determination means 74 determines a solution from among the multiple solutions derived by the annealing execution means 73, based on a solution determination rule for determining a solution among the multiple new solutions and the given solution to the combinatorial optimization problem.

Abstract: A loudspeaker device includes: a magnetic circuit that includes a yoke, a magnet, and a top plate; a voice coil body; a diaphragm; and a frame that holds the yoke and the diaphragm. The frame includes a through hole that holds the yoke at a predetermined position with the yoke being inserted into the through hole. The yoke includes a protrusion portion that abuts an outer peripheral surface portion of the frame that defines the through hole, with the magnetic gap being inside the frame.

Abstract: The difference matrix calculation means 72 calculates a difference matrix which is a difference between a first matrix representing a combinatorial optimization problem for which a solution was found last time and a second matrix representing the latest combinatorial optimization problem. The difference matrix compression means 73 compresses the difference matrix. The transmission means 74 transmits the difference matrix after compression to a combinatorial optimization problem solution device that finds a solution to the combinatorial optimization problem.

Abstract: A state output system includes a solving unit which executes a solving process for solving a combinatorial optimization problem by a simulated annealing method, an acquiring unit which acquires data indicating states of the solving process in execution from the solving unit, and an outputting unit which outputs the acquired data during the execution of the solving process.

Abstract: An information processing apparatus includes: a receiver configured to receive an input operation of a user; and a display controller configured to display, in a display area having a first area and a second area, an image. The display controller includes: an icon controller configured to display, in the second area, first icons associated one-to-one with different layouts in splitting the first area, and a first splitter configured to split the first area into split areas based on a layout corresponding to a selected first icon to when the receiver receives an input operation for selecting any of the first icons.

Abstract: A solution accuracy guaranteeing annealing calculation device includes a first solving unit which solves a combinatorial optimization problem by an annealing method, and a second solving unit which solves a relaxation problem, which is a problem generated by relaxing constraints imposed on the combinatorial optimization problem, wherein the second solving unit calculates, if the combinatorial optimization problem is a minimization problem, a lower bound of a minimization target in the minimization problem by solving the relaxation problem generated from the combinatorial optimization problem, and calculates, if the combinatorial optimization problem is a maximization problem, an upper bound of a maximization target in the maximization problem by solving the relaxation problem generated from the combinatorial optimization problem.

Abstract: An engine is an engine provided with a first cylinder row and a second cylinder row. The engine includes: a controller that is placed in an intra-bank area positioned between the first cylinder row and the second cylinder row; and a fuel pipe that is placed below the controller in the intra-bank area and included in a passage of a fuel. Ina plan view from an up and down direction, a joint portion possessed by the fuel pipe is displaced from the controller.

Abstract: An engine includes an engine stop switch for stopping the engine, and a cooling part included in a holding portion or passage of a cooling liquid. The engine stop switch is placed at the cooling part or at a peripheral part of the cooling part.

Abstract: One solid preparation of the present invention mainly includes silicon fine particles, and has a capability of generating hydrogen. In addition, one specific example of the solid preparation mainly includes silicon fine particles having a crystallite diameter principally of 1 nm or more and 100 nm or less, and exhibits a capability of generating hydrogen in an amount of 3 ml/g or more when brought into contact with a water-containing liquid having a pH value of 7 or more. In this solid preparation, hydrogen is generated when the silicon fine particles are brought into contact with a water-containing liquid having a pH value of 7 or more. Therefore, taking advantage of the characteristics of the solid preparation, generation of hydrogen is promoted in, for example, a gastrointestinal tract where the pH value is 7 or more due to secretion of pancreatic fluid after passage through the stomach after oral ingestion.

Abstract: An engine includes a sacrificial protective pipe subjected to a sacrificial protective coating process, and a metal pipe connected to at least one of two ends of the sacrificial protective pipe. The engine includes a flow path component (an intercooler side cover, a fresh-water cooler side cover) connected to one of two ends of the metal pipe, the one not being connected to the sacrificial protective pipe, and a sacrificial protective material provided to the flow path component.

Abstract: The term generation means 73 generates a term, when a solution to a combinatorial optimization problem, an energy function, which is used to obtain the solution, of a model representing states of individual spins by a first value or a second value, and a pair of identification information of spin and degree of wish to change which indicates degree to which an user wishes to change state of spin corresponding to the identification information in the solution are given, wherein the term is generated for each pair of the identification information and the degree of wish to change, based on the state of spin corresponding to the identification information in the solution and the degree of wish to change. The energy function derivation means 74 deriving a new energy function by adding terms generated by the term generation means 73 for each pair to the energy function.

Abstract: One compound (100) according to the present invention contains silicon fine particles having a capability of generating hydrogen or aggregates of the silicon fine particles. The compound that contains the silicon fine particles or the aggregates having a capability of generating hydrogen is capable of generating hydrogen in the body of, for example, an animal that has ingested the compound. For a plant, the compound can be disposed or charged into, for example, moisture (water-containing liquid) or fertilizer to be provided to the plant, to supply the plant with hydrogen generated from the compound.

Abstract: A method of disassembling a steam generator including a body portion, a water chamber, a tube plate and a plurality of heat transfer tubes, the method includes: a step of obtaining a disassembly target including the tube plate and a part of the heat transfer tubes; a step of specifying the heat transfer tube fixed to the tube plate; a step of releasing fixation between the part of the heat transfer tube and the tube plate; and a step of pulling out the part of the heat transfer tube from the through-hole, in the step of releasing the fixation, the TIG heating head is inserted from the primary region side, and in the step of releasing the fixation, the TIG heating head is moved to a plurality of streaks only in a direction from the primary region side to the secondary region side.

Abstract: Provided is a technology related to a horseshoe crab factor B variant, and also provided is means for performing endotoxin measurement with high sensitivity. A polypeptide having an amino acid sequence in which the amino acid residue at the 193-position in an amino acid sequence of a polypeptide of horseshoe crab factor B is substituted with a cysteine (Cys) residue, is produced. Endotoxin measurement can be carried out with high sensitivity by configuring a Limulus reagent by combining this polypeptide with horseshoe crab factor C.

Abstract: Provided is an information processing apparatus configured for determining an encryption target from a plurality of weights of a model trained by deep learning, the information processing apparatus includes an encryption target weight selection means for selecting, from among the plurality of weights, a weight of an encryption target, an encryption target weight changing means for changing the selected weight in the trained model, an inference accuracy evaluation means for evaluating an inference accuracy of the trained model with the changed weight, and a control means for repeating selection of the weight by the encryption target weight selection unit until the inference accuracy reaches a target accuracy or less.

Abstract: A layered solid formulation as one hydrogen supply material according to the present invention includes silicon fine particles having a capability of generating hydrogen and aggregates of the silicon fine particles, and a physiologically acceptable medium that gets contact with the silicon fine particles or the aggregates thereof. The hydrogen supply material is a hydrogen supply material for bringing the hydrogen into contact with the skin and/or the mucous membrane through the medium.

Abstract: An oxidative stress inhibitor 100 of the present invention contains silicon particles capable of generating hydrogen. In a preferred aspect of the oxidative stress inhibitor 100, the following effects (a) and/or (b) can be exhibited. (a) The total amount of generation (total amount of production) is increased. (b) The amount of generation of hydrogen per unit time (i.e. rate of generation of hydrogen), particularly the rate of generation of hydrogen in the initial stage is increased.

Abstract: An engine system in which blow-by gas with a specific gravity less than 1 with reference to air is generatable includes a cylinder block. The cylinder block includes a cylinder and a crank chamber which are arranged in an up/down direction, the crank chamber being positioned below the cylinder. An internal peripheral face of the cylinder block has a ventilation port that connects to a ventilation passage that connects an internal space of the crank chamber with an external space out of the cylinder block, and that is open. The ventilation port is placed above a center in the up/down direction in the crank chamber.