Patents by Inventor Yuki MIZUKAMI

Yuki MIZUKAMI has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20230312474
    Abstract: A compound represented by formula (2) or pharmaceutically acceptable salt thereof: wherein R1 represents a hydrogen atom or the like; R2 represents a methoxy group or the like; R3 represents a hydrogen atom or the like; R4 represents an optionally substituted C1-6 alkyl group or the like; m represents 0, 1, or 2; n represents 0, 1, 2, or 3; L1 represents —NH—C(?O)—, —C(?O)—NH—, or the like; L2 represents a single bond or the like; X represents optionally substituted phenyl or the like; Y represents optionally substituted phenyl or the like; and X and Y are bonded at a carbon atom on each ring.
    Type: Application
    Filed: September 3, 2021
    Publication date: October 5, 2023
    Applicant: Sumitomo Pharma Co., Ltd.
    Inventors: Kozo YOSHIDA, Hiroyuki KITANO, Yuki MIZUKAMI
  • Publication number: 20230287009
    Abstract: Provided is a novel compound that has an excellent ?-lactamase inhibitory effect. More specifically, provided is a compound represented by formula (1a), (1b) or (11) having an excellent ?-lactamase inhibitory effect or a pharmaceutically acceptable salt thereof. By using this compound either in combination with a ?-lactam drug or alone, a useful preventive or therapeutic agent for bacterial infections is provided. Also provided are useful preventive or therapeutic agents for treating various diseases with the combined use of the aforesaid compound and ?-lactam drugs.
    Type: Application
    Filed: April 28, 2023
    Publication date: September 14, 2023
    Applicants: Sumitomo Pharma Co., Ltd., THE KITASATO INSTITUTE
    Inventors: Toshio KANAI, Sachiko KOIKE, Takayuki FUKAYA, Shunichiro UESUGI, Shingo MIZUSHIMA, Hitoshi SUDA, Yuki MIZUKAMI, Yohei IKUMA, Toshiaki SUNAZUKA, Yoshihiko NOGUCHI
  • Patent number: 11702431
    Abstract: Provided is a novel compound that has an excellent ?-lactamase inhibitory effect. More specifically, provided is a compound represented by formula (1a), (1b) or (11) having an excellent ?-lactamase inhibitory effect or a pharmaceutically acceptable salt thereof. By using this compound either in combination with a ?-lactam drug or alone, a useful preventive or therapeutic agent for bacterial infections is provided. Also provided are useful preventive or therapeutic agents for treating various diseases with the combined use of the aforesaid compound and ?-lactam drugs.
    Type: Grant
    Filed: April 26, 2019
    Date of Patent: July 18, 2023
    Assignees: Sumitomo Pharma Co., Ltd., THE KITASATO INSTITUTE
    Inventors: Toshio Kanai, Sachiko Koike, Takayuki Fukaya, Shunichiro Uesugi, Shingo Mizushima, Hitoshi Suda, Yuki Mizukami, Yohei Ikuma, Toshiaki Sunazuka, Yoshihiko Noguchi
  • Patent number: 11066425
    Abstract: Provided is a novel compound that has an excellent ?-lactamase inhibitory effect. More specifically, provided is a compound represented by formula (1a), (1b) or (11) having an excellent ?-lactamase inhibitory effect or a pharmaceutically acceptable salt thereof. By using this compound either in combination with a ?-lactam drug or alone, a useful preventive or therapeutic agent for bacterial infections is provided. Also provided are useful preventive or therapeutic agents for treating various diseases with the combined use of the aforesaid compound and ?-lactam drugs.
    Type: Grant
    Filed: December 29, 2020
    Date of Patent: July 20, 2021
    Assignees: SUMITOMO DAINIPPON PHARMA CO., LTD., THE KITASATO INSTITUTE
    Inventors: Toshio Kanai, Sachiko Koike, Takayuki Fukaya, Shunichiro Uesugi, Shingo Mizushima, Hitoshi Suda, Yuki Mizukami, Yohei Ikuma, Toshiaki Sunazuka, Yoshihiko Noguchi
  • Publication number: 20210147448
    Abstract: Provided is a novel compound that has an excellent ?-lactamase inhibitory effect. More specifically, provided is a compound represented by formula (1a), (1b) or (11) having an excellent ?-lactamase inhibitory effect or a pharmaceutically acceptable salt thereof. By using this compound either in combination with a ?-lactam drug or alone, a useful preventive or therapeutic agent for bacterial infections is provided. Also provided are useful preventive or therapeutic agents for treating various diseases with the combined use of the aforesaid compound and ?-lactam drugs.
    Type: Application
    Filed: April 26, 2019
    Publication date: May 20, 2021
    Applicants: SUMITOMO DAINIPPON PHARMA CO., LTD., THE KITASATO INSTITUTE
    Inventors: Toshio KANAI, Sachiko KOIKE, Takayuki FUKAYA, Shunichiro UESUGI, Shingo MIZUSHIMA, Hitoshi SUDA, Yuki MIZUKAMI, Yohei IKUMA, Toshiaki SUNAZUKA, Yoshihiko NOGUCHI