Abstract: A vehicle interior purification device includes: first and second outlets disposed in a housing; first and second blower fans corresponding to the first and second outlets and disposed inside the housing; and a predetermined generation device for an airflow delivered from the first outlet and the second outlet, the predetermined generation device being disposed inside the housing. The predetermined generation device includes at least one of an electrostatic atomization device that generates a mist containing charged water particles and an ozone/ion generation device that generates ozone and negative ions by corona discharge. The first outlet and the second outlet are set to be disposed along a direction of travel of the vehicle. The first rotational speed of the first blower fan and a second rotational speed of the second blower fan are settable to different rotational speeds.

Abstract: A vehicle according to the present disclosure includes a first wheel, a second wheel, a body coupled to the first and second wheels and movable by the first and second wheels, a first imaging circuit configured to capture an image of exterior of the vehicle, and a processor. The processor is configured to: set a monitoring target based on a captured image; start, when a monitoring start condition is met, a monitoring process of determining whether the monitoring target belongs to a monitoring range based on a captured image by the first imaging circuit; and terminate, when a monitoring end condition is met, the monitoring process, the monitoring start condition or the monitoring end condition including a condition related to an operation of the vehicle.

Abstract: Embodiments of the disclosure encompass methods and compositions related to overcoming or preventing cancer resistance to anti-apoptotic proteins, for example BH3 mimetics. The disclosure provides methods for modulating p73 to reduce cancer resistance to BH3 mimetics including inhibitors of Bcl-2, Bcl-xL, Mcl-1, Bcl-W, A1/BFL-1, or a combination thereof. In specific embodiments, targeting isoforms of p73, such as TAp73 or DNp73, results in reduction of cancer resistance to BH3 mimetics to allow effective treatment of hematological cancers.

Abstract: A variable oil pump includes a pump housing, an oil pump rotor housed in the pump housing and rotationally driven, an adjustment member housed in the pump housing and adjusting an oil discharge amount from the oil pump rotor by being displaced due to a drive force while rotatably holding the oil pump rotor from an outer peripheral side, and a guide portion including a groove provided in the adjustment member and a pin provided on the pump housing and engaging with the groove. The guide portion guides relative displacement of the adjustment member with respect to the pump housing by engaging the groove and the pin with each other, and an inner surface of the groove and an outer surface of the pin come into line contact with each other along a direction in which the pin extends at an initial position where the adjustment member starts its displacement.

Abstract: A variable displacement oil pump includes an adjustable member that is configured to shift according to changes in pressure inside a control oil chamber. The adjustable member has a long hole. A guide pin is disposed inside the long hole. The guide pin is fixed to either a housing or a cover of the variable displacement oil pump. The width of the long hole is larger at a part of the long hole farther away from a fixed end of the guide pin in its lengthwise direction than at a part thereof closer to the fixed end.

Abstract: A control device for a variable-capacity oil pump provided in an engine using alcohol-containing fuel includes an electronic control unit. The electronic control unit is configured to: (i) estimate an alcohol concentration in oil of the engine, and (ii) correct a capacity of the oil pump to be increased in a correction condition as compared with a case where the correction condition is not established when the correction condition is established. The correction condition is that an estimated alcohol concentration is a predetermined concentration or more and a temperature of the oil is a predetermined temperature or more.

Abstract: A variable oil pump includes a pump housing, an oil pump rotor housed in the pump housing and rotationally driven, an adjustment member housed in the pump housing and adjusting an oil discharge amount from the oil pump rotor by being displaced due to a drive force while rotatably holding the oil pump rotor from an outer peripheral side, and a guide portion including a groove provided in the adjustment member and a pin provided on the pump housing and engaging with the groove. The guide portion guides relative displacement of the adjustment member with respect to the pump housing by engaging the groove and the pin with each other, and an inner surface of the groove and an outer surface of the pin come into line contact with each other along a direction in which the pin extends at an initial position where the adjustment member starts its displacement.

Abstract: A variable displacement oil pump includes: a variable displacement mechanism that is able to change a discharge amount per rotation of an input shaft. The variable displacement mechanism includes a pump housing, an oil pressure chamber provided in the pump housing, and a capacity adjustment member displaced by oil pressure from the oil pressure chamber. The capacity adjustment member is configured to be operated when receiving control oil pressure that is supplied from a control valve to the oil pressure chamber. The pump housing has an oil release hole that is opened to face the oil pressure chamber and that penetrates a wall section of the pump housing to partially release oil.

Abstract: A variable displacement oil pump includes an adjustable member that is configured to shift according to changes in pressure inside a control oil chamber. The adjustable member has a long hole. A guide pin is disposed inside the long hole. The guide pin is fixed to either a housing or a cover of the variable displacement oil pump. The width of the long hole is larger at a part of the long hole farther away from a fixed end of the guide pin in its lengthwise direction than at a part thereof closer to the fixed end.

Abstract: A vehicle light installed in a vehicle includes: a main case having a front opening; a first light guide disposed in the main case; a first light source that emits light into the first light guide; and a headlamp disposed in the main case. The first light guide (i) is rod-shaped, (ii) includes a first extended section extending from the inboard side of the first light guide relative to the vehicle widthwise direction toward the outboard side and a second extended section that continues from the first extended section, curves back inwardly, and extends to the inboard side, and (iii) opens toward a longitudinal center line of the vehicle. The headlamp is disposed between the first extended section and the second extended section. The first extended section and the second extended section extend toward the longitudinal center line of the vehicle to a point beyond the headlamp.

Abstract: A vehicle light installed in a vehicle includes: a main case having a front opening; a first light guide disposed in the main case; a first light source that emits light into the first light guide; and a headlamp disposed in the main case. The first light guide (i) is rod-shaped, (ii) includes a first extended section extending from the inboard side of the first light guide relative to the vehicle widthwise direction toward the outboard side and a second extended section that continues from the first extended section, curves back inwardly, and extends to the inboard side, and (iii) opens toward a longitudinal center line of the vehicle. The headlamp is disposed between the first extended section and the second extended section. The first extended section and the second extended section extend toward the longitudinal center line of the vehicle to a point beyond the headlamp.

Abstract: A vehicle light installed in a vehicle includes: a main case having a front opening; first and second light guides that are disposed in the main case; light sources that emit light into the first and second light guides; and a translucent cover fitted to cover the opening of the main case. The first light guide is rod-shaped and includes a first extended section extending from the inboard side of the first light guide relative to the vehicle width direction toward the outboard side of the first light guide relative to the same and a second extended section that continues from the first extended section, curves back inwardly, and extends to the inboard side, and the second light guide is plate-shaped and disposed so as to pass in front of or behind the portion of the first light guide that curves back.

Abstract: A valve control mechanism is configured that is capable of optimally controlling an engine by lifting an intake valve only by the necessary amount, while suppressing noise at the time of operation. This valve control mechanism includes a control member that rotates around a control axis due to a driving force of an actuator, and a base end portion of a rocker arm is pivotably supported around a pivot axis by an eccentric support portion of the control member. The rocker arm is pivoted by a cam portion of a camshaft abutting against an intermediate roller of the rocker arm, and an operation of opening the intake valve is performed due to a pressure force from the pivot end. The rocker arm is shifted in the longitudinal direction due to an operation of the actuator, and control for changing the lift amount of the intake valve is performed.

Abstract: A control device for a variable-capacity oil pump provided in an engine using alcohol-containing fuel includes an electronic control unit. The electronic control unit is configured to: (i) estimate an alcohol concentration in oil of the engine, and (ii) correct a capacity of the oil pump to be increased in a correction condition as compared with a case where the correction condition is not established when the correction condition is established. The correction condition is that an estimated alcohol concentration is a predetermined concentration or more and a temperature of the oil is a predetermined temperature or more.

Abstract: A guide slot having an elongated-hole shape is formed in a capacity adjustment member, so that displacement of the capacity adjustment member is regulated, by a guide pin inserted into the guide slot, to a longitudinal direction of the guide slot. Two spaces separated by the guide pin into one side and the other side in the longitudinal direction of the guide slot are formed inside the guide slot, and a communicating passage is provided so as to communicate the spaces with each other.

Abstract: A lash adjuster is configured that reduces the impact at the time when a pressure force is exerted on a pressure-receiving effector, and reliably opens a valve by the necessary amount. This lash adjuster includes, in a relatively movable manner, the pressure-receiving effector that receives the pressure force and a relay effector that performs an operation of opening an intake valve, a pressure receiving-side damper space is formed at an insertion portion thereof, and an orifice portion is formed that suppresses an outflow of oil in the pressure receiving-side damper space when the pressure-receiving effector and the relay effector move in approaching directions. An abutting portion is formed that directly transmits the pressure force of the pressure-receiving effector to the relay effector when the pressure-receiving effector and the relay effector approach each other.

Abstract: A variable displacement oil pump includes: a variable displacement mechanism that is able to change a discharge amount per rotation of an input shaft. The variable displacement mechanism includes a pump housing, an oil pressure chamber provided in the pump housing, and a capacity adjustment member displaced by oil pressure from the oil pressure chamber. The capacity adjustment member is configured to be operated when receiving control oil pressure that is supplied from a control valve to the oil pressure chamber. The pump housing has an oil release hole that is opened to face the oil pressure chamber and that penetrates a wall section of the pump housing to partially release oil.

Abstract: An oil pump includes: an inner rotor rotatable with a drive shaft in a unified manner on a drive-rotation axis; an outer rotor which has inner teeth configured to engage with outer teeth of the inner rotor and is rotatable about a driven axis eccentric to the drive-rotation axis; and an adjustment ring for rotatably supporting the outer rotor. A guide means which allows the adjustment ring to rotate about the driven axis, while allowing the driven axis to revolve about the drive-rotation axis, is formed of: first and second arm portions provided on the adjustment ring; and first and second guide faces with which the first and second arm portions are brought into slidable contact.

Abstract: A vehicle light installed in a vehicle includes: a main case having a front opening; first and second light guides that are disposed in the main case; light sources that emit light into the first and second light guides; and a translucent cover fitted to cover the opening of the main case. The first light guide is rod-shaped and includes a first extended section extending from the inboard side of the first light guide relative to the vehicle width direction toward the outboard side of the first light guide relative to the same and a second extended section that continues from the first extended section, curves back inwardly, and extends to the inboard side, and the second light guide is plate-shaped and disposed so as to pass in front of or behind the portion of the first light guide that curves back.

Abstract: A valve control mechanism is configured that is capable of optimally controlling an engine by lifting an intake valve only by the necessary amount, while suppressing noise at the time of operation. This valve control mechanism includes a control member that rotates around a control axis due to a driving force of an actuator, and a base end portion of a rocker arm is pivotably supported around a pivot axis by an eccentric support portion of the control member. The rocker arm is pivoted by a cam portion of a camshaft abutting against an intermediate roller of the rocker arm, and an operation of opening the intake valve is performed due to a pressure force from the pivot end. The rocker arm is shifted in the longitudinal direction due to an operation of the actuator, and control for changing the lift amount of the intake valve is performed.