Abstract: To provide a method for producing a fluorinated copolymer, whereby it is possible to efficiently produce a fluorinated copolymer in which coloration and foaming are suppressed during heating. A method for producing a fluorinated copolymer, comprising a step of producing a fluorinated copolymer by polymerizing tetrafluoroethylene and other monomer other than the tetrafluoroethylene in the presence of a hydroperoxide, at least one selected from the group consisting of a sulfite, a hydrogen sulfite, a dithionite, and a metabisulfite, at least one selected from the group consisting of an acidic substance and a substance that generates an acid by hydrolysis, and an aqueous medium.

Abstract: Provided is a method of producing a fluorine-containing copolymer, the method including carrying out solution polymerization using monomers including ethylene and tetrafluoroethylene, in a polymerization medium containing at least one polymerization solvent A selected from the group consisting of compounds represented by Formula 1 to Formula 4. Also provided is a fluorine-containing copolymer. Descriptions for Formula 1 to Formula 4 are omitted.

Abstract: Provided are a chimeric antigen receptor comprising an extracellular domain capable of binding to an antigen, a transmembrane domain and at least one intracellular domain, the chimeric antigen receptor being characterized in that an intracellular domain of a glucocorticoid-induced tumor necrosis factor receptor (GITR) is contained as the intracellular domain; a nucleic acid encoding the chimeric antigen receptor; a cell expressing the chimeric antigen receptor; and a method for producing the cell.

Abstract: Provided are a chimeric antigen receptor comprising an extracellular domain capable of binding to an antigen, a transmembrane domain and at least one intracellular domain, the chimeric antigen receptor being characterized in that an intracellular domain of a glucocorticoid-induced tumor necrosis factor receptor (GITR) is contained as the intracellular domain; a nucleic acid encoding the chimeric antigen receptor; a cell expressing the chimeric antigen receptor; and a method for producing the cell.

Abstract: The present invention provides Ti-4 protein, which is a protein obtained from salivary gland of Triatoma infestans, and the present invention provides Ti-4 gene encoding the protein. As the Ti-4 protein exhibits inhibitory activity on platelet aggregation, a medicine comprising the Ti-4 protein as an active ingredient will serve as a platelet aggregation inhibitor possibly effective for prevention and treatment of myocardial infarction, pulmonary infarction and cerebral infarction. Moreover, the Ti-4 protein will also serve as a highly prospective lead compound in the development of novel platelet aggregation inhibitors.

Abstract: The present invention provides Ti-3 protein, which is a protein obtained from salivary gland of Triatoma infestans, and the present invention provides Ti-3 gene encoding the protein. As the Ti-3 protein exhibits inhibitory activity on platelet aggregation, a medicine comprising the Ti-3 protein as an active ingredient will serve as a platelet aggregation inhibitor possibly effective for prevention and treatment of myocardial infarction, pulmonary infarction and cerebral infarction. Moreover, the Ti-3 protein will also serve as a highly prospective lead compound in the development of novel platelet aggregation inhibitors.

Abstract: The present invention provides Ti-3 protein, which is a protein obtained from salivary gland of Triatoma infestans, and the present invention provides Ti-3 gene encoding the protein. As the Ti-3 protein exhibits inhibitory activity on platelet aggregation, a medicine comprising the Ti-3 protein as an active ingredient will serve as a platelet aggregation inhibitor possibly effective for prevention and treatment of myocardial infarction, pulmonary infarction and cerebral infarction. Moreover, the Ti-3 protein will also serve as a highly prospective lead compound in the development of novel platelet aggregation inhibitors.

Abstract: The present invention provides Ti-4 protein, which is a protein obtained from salivary gland of Triatoma infestans, and the present invention provides Ti-4 gene encoding the protein. As the Ti-4 protein exhibits inhibitory activity on platelet aggregation, a medicine comprising the Ti-4 protein as an active ingredient will serve as a platelet aggregation inhibitor possibly effective for prevention and treatment of myocardial infarction, pulmonary infarction and cerebral infarction. Moreover, the Ti-4 protein will also serve as a highly prospective lead compound in the development of novel platelet aggregation inhibitors.