Patents by Inventor Yukihiko Saeki

Yukihiko Saeki has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20100234407
    Abstract: The present invention provides a preventive or therapeutic drug for a myeloma tumor and osteoclastic bone loss associating therewith, the drug containing as an active ingredient an osteopontin-production regulator or inhibitor; a screening method for a preventive or therapeutic drug for a myeloma tumor, characterized by determining osteopontin production regulatory or inhibitory effect; as well as a diagnostic kit for a myeloma tumor, characterized by including a reagent for measuring blood osteopontin level, and a diagnostic method.
    Type: Application
    Filed: January 4, 2010
    Publication date: September 16, 2010
    Applicant: KOWA CO., LTD.
    Inventors: Yukihiko Saeki, Hideyuki Kobayashi, Yuichiro Tabunoki
  • Patent number: 7745154
    Abstract: The present invention provides a preventive or therapeutic drug for a myeloma tumor and osteoclastic bone loss associating therewith, the drug containing as an active ingredient an osteopontin-production regulator or inhibitor; a screening method for a preventive or therapeutic drug for a myeloma tumor, characterized by determining osteopontin production regulatory or inhibitory effect; as well as a diagnostic kit for a myeloma tumor, characterized by including a reagent for measuring blood osteopontin level, and a diagnostic method.
    Type: Grant
    Filed: March 19, 2003
    Date of Patent: June 29, 2010
    Assignee: Kowa Co., Ltd.
    Inventors: Yukihiko Saeki, Hideyuki Kobayashi, Yuichiro Tabunoki
  • Publication number: 20080069815
    Abstract: An anti-osteopontin antibody which inhibits the binding of an integrin recognizing RGD sequence to osteopontin or its fragment, and which inhibits the binding of an integrin recognizing SVVYGLR sequence or sequence equivalent thereto to osteopontin or its fragment. This antibody is useful in remedies for autoimmune diseases, remedies for rheumatism and remedies for rheumatoid arthritis. Also, a method of treating autoimmune disease, rheumatism or rheumatoid arthritis is provided. This antibody is useful in diagnostics and a diagnostic method for rheumatism too.
    Type: Application
    Filed: August 8, 2007
    Publication date: March 20, 2008
    Applicants: IMMUNO-BIOLOGICAL LABORATORIES CO., LTD., Astellas Pharma Inc.
    Inventors: Toshimitsu UEDE, Shigeyuki Kon, Yukihiko Saeki, Yasuyuki Yokosaki, Masaki Noda, Nobuchika Yamamoto
  • Publication number: 20070142281
    Abstract: The present invention provides a preventive or therapeutic drug for a myeloma tumor and osteoclastic bone loss associating therewith, the drug containing as an active ingredient an osteopontin-production regulator or inhibitor; a screening method for a preventive or therapeutic drug for a myeloma tumor, characterized by determining osteopontin production regulatory or inhibitory effect; as well as a diagnostic kit for a myeloma tumor, characterized by including a reagent for measuring blood osteopontin level, and a diagnostic method.
    Type: Application
    Filed: August 11, 2006
    Publication date: June 21, 2007
    Applicant: KOWA CO., LTD.
    Inventors: Yukihiko Saeki, Hideyuki Kobayashi, Yuichiro Tabunoki
  • Publication number: 20070021418
    Abstract: This invention relates to a method of inhibiting OPN production, which comprises administering an effective amount of a pyridazine derivative represented by the following formula (I) or a salt thereof: wherein: R1 means a substituted or unsubstituted phenyl or pyridyl group; R2 means a substituted phenyl group; R3 means a hydrogen atom or a substituted or unsubstituted phenyl or pyridyl group; A means a single bond, a C1-6 linear or branched alkylene group, or a C2-9 linear or branched alkenylene group; and X means an oxygen atom or a sulfur atom.
    Type: Application
    Filed: July 29, 2004
    Publication date: January 25, 2007
    Applicant: Kowa Co., LTD.
    Inventors: Yukihiko Saeki, Yuichiro Tabunoki, Tomoyuki Koshi
  • Publication number: 20050250162
    Abstract: The present invention provides a preventive or therapeutic drug for a myeloma tumor and osteoclastic bone loss associating therewith, the drug containing as an active ingredient an osteopontin-production regulator or inhibitor; a screening method for a preventive or therapeutic drug for a myeloma tumor, characterized by determining osteopontin production regulatory or inhibitory effect; as well as a diagnostic kit for a myeloma tumor, characterized by including a reagent for measuring blood osteopontin level, and a diagnostic method.
    Type: Application
    Filed: March 19, 2003
    Publication date: November 10, 2005
    Applicant: KOWA CO., LTD.
    Inventors: Yukihiko Saeki, Hideyuki Kobayashi, Yuichiro Tabunoki
  • Publication number: 20040234524
    Abstract: An anti-osteopontin antibody which inhibits the binding of an integrin recognizing RGD sequence to osteopontin or its fragment, and which inhibits the binding of an integrin recognizing SVVYGLR sequence or sequence equivalent thereto to osteopontin or its fragment. This antibody is useful in remedies for autoimmune diseases, remedies for rheumatism and remedies for rheumatoid arthritis. Also, a method of treating autoimmune disease, rheumatism or rheumatoid arthritis is provided. This antibody is useful in diagnostics and a diagnostic method for rheumatism too.
    Type: Application
    Filed: May 20, 2004
    Publication date: November 25, 2004
    Inventors: Toshimitsu Uede, Shigeyuki Kon, Yukihiko Saeki, Yasuyuki Yokosaki, Masaki Noda, Nobuchika Yamamoto