Abstract: An apparatus for evaluating a vascular endothelial function, includes: a cuff pressure controlling unit configured to perform continuous pressure stimulation on a part of a body of a subject for a predetermined time, by using a cuff adapted to be wrapped around the part of the body of the subject; a cuff pressure detecting unit configured to detect a cuff pressure from an output of a pressure sensor connected to the cuff; a pulse wave detecting unit configured to detect a pulse wave from the output of the pressure sensor; and an analyzing unit configured to evaluate the vascular endothelial function by comparing vessel viscoelastic indexes which are obtained from the pulse wave detected in two of zones before, during, and after the pressure stimulation, and which exclude an amplitude of the pulse wave.

Abstract: An apparatus for evaluating a vascular endothelial function using a first cuff that occludes an artery of a patient, measuring pulse waves from pressure of a second cuff at a different position than the first cuff, and evaluating the vascular endothelial function using the pulse waves.

Abstract: An apparatus for evaluating a vascular endothelial function includes: a cuff, to be wound around a part of a body of a subject; a cuff pressure controller, configured to control a pressure of the cuff, and configured to apply continuous pressure stimulation; a cuff pressure detector, configured to detect the pressure of the cuff from output of a pressure sensor connected to the cuff; a pulse wave detector, configured to detect, from the output of the pressure sensor, pulse waves before and after the continuous pressure stimulation is applied; and an analyzer, configured to evaluate the vascular endothelial function by comparing the pulse waves detected before and after the continuous pressure stimulation is applied.

Abstract: A vessel wall monitoring apparatus includes: a first detecting unit which detects vessel diameter information based on first biological information obtained from a subject; a first producing unit which differentiates the vessel diameter information detected by the first detecting unit, to produce a vessel diameter function; a second detecting unit which detects blood pressure based on second biological information obtained from the subject; a second producing unit which performs a logarithmic operation on the blood pressure detected by the second detecting unit, to produce a logarithmic blood pressure function; and an outputting unit which produces an impedance model expression by using the vessel diameter function, the logarithmic blood pressure function, and mechanical characteristic values including a stiffness, viscosity, and inertia, and which calculates and outputs at least one of the stiffness, the viscosity, and the inertia based on the impedance model expression.

Abstract: A PGC-1 expression-modulating device (1) according to the present invention includes an ultrasonic wave transmitting section (14) that irradiates a subject living body with ultrasonic waves. This configuration modulates PGC-1 expression in a living body and promotes angiogenesis in which VEGF is involved. This enables promoting angiogenesis in a living body and treating ischemic disease without an excessive burden on a patient.

Abstract: A vessel wall monitoring apparatus includes: a first detecting unit which detects vessel diameter information based on first biological information obtained from a subject; a first producing unit which differentiates the vessel diameter information detected by the first detecting unit, to produce a vessel diameter function; a second detecting unit which detects blood pressure based on second biological information obtained from the subject; a second producing unit which performs a logarithmic operation on the blood pressure detected by the second detecting unit, to produce a logarithmic blood pressure function; and an outputting unit which produces an impedance model expression by using the vessel diameter function, the logarithmic blood pressure function, and mechanical characteristic values including a stiffness, viscosity, and inertia, and which calculates and outputs at least one of the stiffness, the viscosity, and the inertia based on the impedance model expression.

Abstract: An apparatus for evaluating a vascular endothelial function, includes: a first cuff, to be wound around a first body part of a subject; a second cuff, to be wound around a second body part of the subject; a cuff pressure controller, configured to control a cuff pressure of each of the first and second cuffs, and configured to perform continuous pressure stimulation on the first body part of the subject for a time period by using the first cuff; a cuff pressure detector, configured to detect the cuff pressure of the second cuff from an output of a pressure sensor connected to the second cuff; a pulse wave detector, configured to detect, from the output of the pressure sensor, pulse waves before and after the continuous pressure stimulation is performed; and an analyzer, configured to evaluate the vascular endothelial function by comparing the pulse waves detected before and after the continuous pressure stimulation is performed.

Abstract: An apparatus for evaluating a vascular endothelial function includes: a cuff, to be wound around a part of a body of a subject; a cuff pressure controller, configured to control a pressure of the cuff, and configured to apply continuous pressure stimulation; a cuff pressure detector, configured to detect the pressure of the cuff from output of a pressure sensor connected to the cuff; a pulse wave detector, configured to detect, from the output of the pressure sensor, pulse waves before and after the continuous pressure stimulation is applied; and an analyzer, configured to evaluate the vascular endothelial function by comparing the pulse waves detected before and after the continuous pressure stimulation is applied.