Abstract: The present invention provides a Plexin-binding regulating agent containing a cyclic peptide having an Arg-Trp-Thr structure or a Leu-Ser-Trp structure or a pharmaceutically acceptable salt of the cyclic peptide.

Abstract: An agent for inhibiting the action of a target RNA based on RNA interference and ASO with a passenger strand and a guide strand for a target RNA, wherein both ends of double-stranded RNA formed pairing of the passenger strand and the guide strand are blunt ends, and one or two or more selected from the group consisting of the units represented by formula (1) and formula (2) below at the following positions (a) and (b): (a) 5? end side and 3? end side of the passenger strand, (b) 3? end side of the guide strand (in which X represents an oxygen atom or sulfur atom), (in which X represents an oxygen atom or sulfur atom).

Abstract: Primers, probes and kits for detection of Rickettsiaceare provided. Also provided are method and system for sensitive and specific detection of Rickettsiaceae using total nucleic acid isolated from a sample in a real-time reverse transcription PCR (Rrt-PCR), e.g. wherein 23S region is amplified and detected.

Abstract: A lactic acid bacterium having increased immunopotentiating activity with being mixed with no ester compound of polyol and a fatty acid is provided. A method for producing a lactic acid bacterium whose immunopotentiating activity is increased without coexisting with ester compound of polyol and a fatty acid, comprising: contacting a lactic acid bacterial immunopotentiating activity-increasing composition comprising an ester compound of a polyol and a fatty acid as an active ingredient with a lactic acid bacterium having immunopotentiating activity and then washing the lactic acid bacterium to remove the lactic acid bacterial immunopotentiating activity-increasing composition.

Abstract: A lactic acid bacterium having increased immunopotentiating activity with being mixed with no ester compound of polyol and a fatty acid is provided. A method for producing a lactic acid bacterium whose immunopotentiating activity is increased without coexisting with ester compound of polyol and a fatty acid, comprising: contacting a lactic acid bacterial immunopotentiating activity-increasing composition comprising an ester compound of a polyol and a fatty acid as an active ingredient with a lactic acid bacterium having immunopotentiating activity and then washing the lactic acid bacterium to remove the lactic acid bacterial immunopotentiating activity-increasing composition.

Abstract: An object of the present invention is to provide apparatuses for examining/diagnosing clinical disease of cancer, systemic lupus erythematosus (SLE), or antiphospholipid antibody syndrome. Blood, blood-derived component, urine, sweat, nail, skin, or hair is irradiated with light having a wavelength of 400 to 2,500 nm or a part of the range, of which the reflection light, the transmission light, or the transmission reflection light is then detected to give spectroscopic absorbance data, and afterward a previously prepared analysis model is used to analyze the absorbance over the whole wavelengths or at a specific wavelength for the measurement to allow the achievement of the object.