Patents by Inventor Yukiko Maeda

Yukiko Maeda has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • CAPSID VARIANTS AND USES THEREOF
    Publication number: 20240207441
    Abstract: Aspects of the disclosure relate to compositions and methods for delivering a transgene (e.g., an anti-inflammatory transgene encoding one or more gene products) to a joint. The disclosure is based, in part, on adeno-associated virus (AAV) capsid protein variants characterized by tropisms for joint tissues (e.g., cartilage, skin, muscle, and bone cells). Methods of treating arthritis in a joint by administering an rAAV comprising the AAV capsid protein variants are also described by the disclosure.
    Type: Application
    Filed: April 26, 2022
    Publication date: June 27, 2024
    Applicant: University of Massachusetts
    Inventors: Yukiko Maeda, Phillip Tai, Guangping Gao