Patents by Inventor Yukio Shigeta

Yukio Shigeta has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 4803158
    Abstract: This invention relates to a composition for determining .beta.-hydroxybutyric acid, usable for doctors, nurses, and patients themselves simply and quickly without use of special instruments, and also relates to a method for preparing the said composition.The composition of the invention oxidizes .beta.-hydroxybutyric acid under alkaline conditions and the presence of nicotineamide adenine dinucleotide (NAD) by .beta.-hydroxybutyric acid dehydrogenase, and the produced reduction-type NAD (NADH) reduces tetrazolium salt through an electron carrier to produce formazan developing color. The composition permits accurate measurement quickly and simply, and has excellent conservative stability, because it is a uniform solid-phase composition prepared by applying reagents necessary for the reaction of film impermeable to water together with a natural or synthesized film forming polymer.
    Type: Grant
    Filed: October 23, 1986
    Date of Patent: February 7, 1989
    Assignees: Kabushiki Kaisha Kyoto Daiichi Kagaku, Kabushiki Kaisha Sanwa Kagaku Kenkyusho
    Inventors: Yukio Shigeta, Yutaka Harano, Shigeki Yamada, Yoshinori Takahaski
  • Patent number: 4722893
    Abstract: Reagents for enzyme immunoassay for apolipoprotein B comprising human apolipoprotein B as a standard antigen, peroxidase-labeled Fab' as an antibody, IgG-coated polystyrene balls, a coloring or fluorescent reagent, hydrogen peroxide as a reaction substrate, a reaction stopper, and buffer solutions.Use of these reagents permits accurate and prompt quantification of apolipoprotein B concentration in serum.
    Type: Grant
    Filed: July 5, 1984
    Date of Patent: February 2, 1988
    Assignee: Shiraimatsu Shinyaku Kabushiki Kaisha
    Inventors: Yukio Shigeta, Yutaka Harano, Takamitsu Nakano, Hideo Nishikawa
  • Patent number: 4261885
    Abstract: Novel somatostatin analogs exhibiting high activity in inhibiting insulin glucagon and growth hormone secretion are depicted by the formula: ##STR1## and pharmaceutically acceptable acid addition salts thereof.
    Type: Grant
    Filed: October 11, 1979
    Date of Patent: April 14, 1981
    Assignee: Shiraimatsu Shingaku Co., Ltd.
    Inventors: Shunpei Sakakibara, Yukio Shigeta